Gene loci information

Transcript annotation

  • This transcript has been annotated as Aldo-keto reductase family 1 member B1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15759 g15759.t14 TTS g15759.t14 6681153 6681153
chr_4 g15759 g15759.t14 isoform g15759.t14 6681640 6683765
chr_4 g15759 g15759.t14 exon g15759.t14.exon1 6681640 6681990
chr_4 g15759 g15759.t14 cds g15759.t14.CDS1 6681740 6681990
chr_4 g15759 g15759.t14 exon g15759.t14.exon2 6682046 6682643
chr_4 g15759 g15759.t14 cds g15759.t14.CDS2 6682046 6682643
chr_4 g15759 g15759.t14 exon g15759.t14.exon3 6683697 6683765
chr_4 g15759 g15759.t14 cds g15759.t14.CDS3 6683697 6683765
chr_4 g15759 g15759.t14 TSS g15759.t14 6683881 6683881

Sequences

>g15759.t14 Gene=g15759 Length=1018
ATGTCAGTTCCATCAGTAAAATTATCAAATGGTCACAGTATTCCAATTATCGGAATTGGT
ACATGGAAGTCACCTACTGGACAAGTTGAACAAGCAGTAAAGGACGCAATTGATGCCGGC
TATCGTCATATTGATTGTGCTTTTGCTTACTTAAATGAAACTGAAGTAGGCAATGCAATT
GCCGCTAAAATTGCAGATGGAACTATCAAGCGTGAAGATATTTTCATTACTTCAAAACTT
TGGAATATTTTTCATGATCCAAAACTTGTTCGAAGTGCAGTTGAAAAATCATTAAAATTT
TTAAAACTTGATTATTTGGATCTTTACTTGATTCATTGGCCAATGGGTTATGCTTATTTG
AATAATGGTGAAACATTATTCCCTAAAAATGAGAAAGAAGAATGGATTTTCTCAGAAGTT
GATTATGTCGACACATGGAAAGCAATGGAGGAATTAGTTGAAGCTGGATTAGTAAAATCA
ATTGGTCTGAGCAATTTCAATTCAAAACAAATCGAACGTGTACTGGCTGTAGCTAAAATC
AAACCAGTAATGAACCAAGTTGAATGCCATCCTTATTTGACACAGAAGAAATTAATTGAA
TTCTGTCGTAGTAAAGGCATTGCTGTTACTGCATATTCACCACTGGGGTCTAACGACCGT
CCTTGGGCAAAACCAGATGATCCACAGCTCATGGATGATCCAAGAATTGTTGCTTTAGCA
GAAAAGTATCAAAAAACTCCAGCTCAAATTCTTATTCGGTATCAAATTCAACGTAGAGTT
GTTGTCATTCCTAAATCAGTCACAAAATCAAGAATCATTAGCAACTTTGATGTTTTTGGC
TTTGAATTATCTTCTGAAGATATTGCAAGTATCGATAGCATTGACTGCAATGGAAGATTG
TGTCATTTGAATTGGTAAGATTAAAAAAATTTTTACTGAACTTTTATTAAGTTTTTTGTA
TTTTTTCAGGGTTTCTCATCATCCACATTATCCATTTGGAACAGACGTTGAATTTTAA

>g15759.t14 Gene=g15759 Length=305
MSVPSVKLSNGHSIPIIGIGTWKSPTGQVEQAVKDAIDAGYRHIDCAFAYLNETEVGNAI
AAKIADGTIKREDIFITSKLWNIFHDPKLVRSAVEKSLKFLKLDYLDLYLIHWPMGYAYL
NNGETLFPKNEKEEWIFSEVDYVDTWKAMEELVEAGLVKSIGLSNFNSKQIERVLAVAKI
KPVMNQVECHPYLTQKKLIEFCRSKGIAVTAYSPLGSNDRPWAKPDDPQLMDDPRIVALA
EKYQKTPAQILIRYQIQRRVVVIPKSVTKSRIISNFDVFGFELSSEDIASIDSIDCNGRL
CHLNW

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g15759.t14 Gene3D G3DSA:3.20.20.100 - 3 305 9.3E-136
2 g15759.t14 PANTHER PTHR11732:SF294 ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 5 301 8.8E-127
3 g15759.t14 PANTHER PTHR11732 ALDO/KETO REDUCTASE 5 301 8.8E-127
14 g15759.t14 PIRSF PIRSF000097 AKR 1 305 2.4E-133
4 g15759.t14 PRINTS PR00069 Aldo-keto reductase signature 36 60 4.3E-58
6 g15759.t14 PRINTS PR00069 Aldo-keto reductase signature 96 114 4.3E-58
7 g15759.t14 PRINTS PR00069 Aldo-keto reductase signature 149 166 4.3E-58
8 g15759.t14 PRINTS PR00069 Aldo-keto reductase signature 183 212 4.3E-58
5 g15759.t14 PRINTS PR00069 Aldo-keto reductase signature 230 254 4.3E-58
1 g15759.t14 Pfam PF00248 Aldo/keto reductase family 17 294 2.3E-55
11 g15759.t14 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 -
10 g15759.t14 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 149 166 -
12 g15759.t14 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 263 278 -
9 g15759.t14 SUPERFAMILY SSF51430 NAD(P)-linked oxidoreductase 6 302 2.23E-104

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0047834 D-threo-aldose 1-dehydrogenase activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed