Gene loci information

Transcript annotation

  • This transcript has been annotated as Aldo-keto reductase family 1 member B1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15759 g15759.t5 isoform g15759.t5 6681124 6682635
chr_4 g15759 g15759.t5 exon g15759.t5.exon1 6681124 6681506
chr_4 g15759 g15759.t5 TTS g15759.t5 6681153 6681153
chr_4 g15759 g15759.t5 exon g15759.t5.exon2 6681602 6681688
chr_4 g15759 g15759.t5 cds g15759.t5.CDS1 6681640 6681688
chr_4 g15759 g15759.t5 exon g15759.t5.exon3 6681744 6681990
chr_4 g15759 g15759.t5 cds g15759.t5.CDS2 6681744 6681990
chr_4 g15759 g15759.t5 exon g15759.t5.exon4 6682046 6682635
chr_4 g15759 g15759.t5 cds g15759.t5.CDS3 6682046 6682370
chr_4 g15759 g15759.t5 TSS g15759.t5 NA NA

Sequences

>g15759.t5 Gene=g15759 Length=1307
TGGACAAGTTGAACAAGCAGTAAAGGACGCAATTGATGCCGGCTATCGTCATATTGATTG
TGCTTTTGCTTACTTAAATGAAACTGAAGTAGGCAATGCAATTGCCGCTAAAATTGCAGA
TGGAACTATCAAGCGTGAAGATATTTTCATTACTTCAAAACTTTGGAATATTTTTCATGA
TCCAAAACTTGTTCGAAGTGCAGTTGAAAAATCATTAAAATTTTTAAAACTTGATTATTT
GGATCTTTACTTGATTCATTGGCCAATGGGTTATGCTTATTTGAATAATGGTGAAACATT
ATTCCCTAAAAATGAGAAAGAAGAATGGATTTTCTCAGAAGTTGATTATGTCGACACATG
GAAAGCAATGGAGGAATTAGTTGAAGCTGGATTAGTAAAATCAATTGGTCTGAGCAATTT
CAATTCAAAACAAATCGAACGTGTACTGGCTGTAGCTAAAATCAAACCAGTAATGAACCA
AGTTGAATGCCATCCTTATTTGACACAGAAGAAATTAATTGAATTCTGTCGTAGTAAAGG
CATTGCTGTTACTGCATATTCACCACTGGGGTCTAACGACCGTCCTTGGGCAAAACCAGA
TGATCCACAGCTCATGGATGATCCAAGAATTGTTGCTTTAGCAGAAAAGTATCAAAAAAC
TCCAGCTCAAATTCTTATTCGGTATCAAATTCAACGTAGAGTTGTTGTCATTCCTAAATC
AGTCACAAAATCAAGAATCATTAGCAACTTTGATGTTTTTGGCTTTGAATTATCTTCTGA
AGATATTGCAAGTATCGATAGCATTGACTGCAATGGAAGATTGTGTCATTTGAATTGGGT
TTCTCATCATCCACATTATCCATTTGGAACAGACGTTGAATTTTAAATATAAAAGTTTCA
AAAAATATTAATTTTTTTATCAAATCAAATTTAATTGATTTAAATCACTGTTACAAAATT
TGCCATTTAAAATTTAATTTGATGGAAAATTACAAGTAAATGGTAAAAAGTTTTGTTGAA
ACTAAGACTTATTTGTAATAGTTTTAACAAACCTTCTTTTTAAATTTAGAATTTTTTCTT
TTAAAGAACAGAAAAATTCAGAAGATTTGTCCAACTATTTTCCAACACTAACAATTTCTT
TCTAATTTTTTTTTTCAAATGAACAAAAATATTTTTTTTTTAATTTTTTTCAAAATAAAA
ATTTATTTACAAAATTGACTTTCATGAGACATTTGGTAAACTTAAAATTTTAATAAATGC
AAAATATATTAACTTTTTAACTTTAACCTTTCAATAAAAAAATATTT

>g15759.t5 Gene=g15759 Length=206
MGYAYLNNGETLFPKNEKEEWIFSEVDYVDTWKAMEELVEAGLVKSIGLSNFNSKQIERV
LAVAKIKPVMNQVECHPYLTQKKLIEFCRSKGIAVTAYSPLGSNDRPWAKPDDPQLMDDP
RIVALAEKYQKTPAQILIRYQIQRRVVVIPKSVTKSRIISNFDVFGFELSSEDIASIDSI
DCNGRLCHLNWVSHHPHYPFGTDVEF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g15759.t5 Gene3D G3DSA:3.20.20.100 - 3 204 3.3E-82
2 g15759.t5 PANTHER PTHR11732:SF402 ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1-A 7 192 1.8E-77
3 g15759.t5 PANTHER PTHR11732 ALDO/KETO REDUCTASE 7 192 1.8E-77
5 g15759.t5 PRINTS PR00069 Aldo-keto reductase signature 35 52 8.4E-34
4 g15759.t5 PRINTS PR00069 Aldo-keto reductase signature 69 98 8.4E-34
6 g15759.t5 PRINTS PR00069 Aldo-keto reductase signature 116 140 8.4E-34
1 g15759.t5 Pfam PF00248 Aldo/keto reductase family 21 180 1.6E-32
8 g15759.t5 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 35 52 -
9 g15759.t5 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 149 164 -
7 g15759.t5 SUPERFAMILY SSF51430 NAD(P)-linked oxidoreductase 7 200 3.01E-60

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0047834 D-threo-aldose 1-dehydrogenase activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed