General information for g15817.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable cytochrome P450 6a18.
Parent gene
- The parent gene g15817 is located on chr_4: 6869203..6871897 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15817 | g15817.t3 | TTS | g15817.t3 | 6867357 | 6867357 |
| chr_4 | g15817 | g15817.t3 | isoform | g15817.t3 | 6867472 | 6869724 |
| chr_4 | g15817 | g15817.t3 | exon | g15817.t3.exon1 | 6867472 | 6867638 |
| chr_4 | g15817 | g15817.t3 | cds | g15817.t3.CDS1 | 6867472 | 6867638 |
| chr_4 | g15817 | g15817.t3 | exon | g15817.t3.exon2 | 6867826 | 6868077 |
| chr_4 | g15817 | g15817.t3 | cds | g15817.t3.CDS2 | 6867826 | 6868077 |
| chr_4 | g15817 | g15817.t3 | exon | g15817.t3.exon3 | 6868258 | 6868394 |
| chr_4 | g15817 | g15817.t3 | cds | g15817.t3.CDS3 | 6868258 | 6868394 |
| chr_4 | g15817 | g15817.t3 | exon | g15817.t3.exon4 | 6868537 | 6868936 |
| chr_4 | g15817 | g15817.t3 | cds | g15817.t3.CDS4 | 6868537 | 6868936 |
| chr_4 | g15817 | g15817.t3 | exon | g15817.t3.exon5 | 6869191 | 6869724 |
| chr_4 | g15817 | g15817.t3 | cds | g15817.t3.CDS5 | 6869191 | 6869470 |
| chr_4 | g15817 | g15817.t3 | TSS | g15817.t3 | 6869787 | 6869787 |
Sequences
>g15817.t3 Gene=g15817 Length=1490
CAATTTCGTTTGTATTGATTTTTTGGTTTGTTAAAAATCGTTTTAATTATTGGAAAAATC
AAAATGTTCCTTTTCTTCAACCAAAATTTCCCTATGGAAATATCAAAGGATTTGGTAAAA
ACTTTCATCAATTTGAATTTCAACAAAAAATCTACGAAATTTATAAGAAGAAACTTTCGC
CATTTGTTGGTCTTTATTATTACATTCAACCAGTTGTTTTATGCACAGACTTGGAATTTA
TCAAAAATATTTTCATGCGTGATTCTGCTTATTTTCTTGATCGTGGCGCTTATTACAATG
AAAAAGACAATCCAATTTCAGCACATCTATTTAATCTTGACAATCCAAAATGGAAAATAT
TAAGGAACAAATTAACGCCAACTTTTACATCAGGAAAGATCAAGACAATGTTTTTTACTC
TTTGTGATGTTGGTGAAAGATTGGTGAAAAAATTAGAAAAAGAAGTAGAAATTGCAGATG
ATGGAATTTTAGAAATGAAGGAATTTTCTGCCAGATTTACAACTGATGTTATTGGTTCAT
TTGGATTTGGGATTGAAATAAATTCCCTTGAGCATCCTGATACTGAATTTAGAGTTCGTG
GAAGTCAGGTTTTTGAAAAGCCAAAATATCCACCAATATTTTTTCAATTTTGTGTGAATT
TCAAACCTTTAGCACGAATGCTTAAAATTAGCACCACTGCTAAAGAAATTGAGGAATTTT
TTACAAGAATTGTAAAAGAAACAATTGAATATCGTGAAAAAAATCAAATAATTCGAAATG
ATTTTATGAATTTGTTGATACAATTGAAAAATTTTGGGAAACTTGAAGGAGACATAACAA
GTATAGGAAAATTGACATTAAATGAAATTGTTGCTCAATGTTTTATCTTTTTTGCTGCTG
GATATGAAACAAGTTCAACTACAATGGCTTATGCTTTATTTGAGTTAGCATTGAACCAAA
ATATTCAAGATAAGGCGAGAGATAATGTAAGAAAAATATTGAGCAAATATGATGGAAAGT
TTACATATGAAGGTCTTATGGAAATGGATTATGTTGACATGTGTGTTAATGAAACTCTCA
GAAAATATCCTCCAGTATCATTCATCACACGATATTGTAGTAATGATTACAAAATAGAAC
ACACAGAACATGTTATCAAAAAAGGTCAACTTGTCATTATTCCAACTTATGCCATTCATC
ATGATAAAGATATTTTCCCTAATCCAGAAGTTTTTGATCCTGAAAGATTTTCACAATTGG
AATCACCAAAAATACCGCAAGTTGCTTTTATGCCTTTTGGACATGGTGCTAGGAATTGTA
TAGGACTTCGCTTTGGACAAATTCAAGCAAAAGTTGGACTGGCAATGTTGCTAAATAATT
TCAAATTTGAGCTGTCGGACAAGACTCAAAATCCATTGAAATTTAGAAAAGATACAATAG
TTATGCTTATTGCTGAAGGTGGAATTCATTTGAAAGTTACCAAAATATAA
>g15817.t3 Gene=g15817 Length=411
MRDSAYFLDRGAYYNEKDNPISAHLFNLDNPKWKILRNKLTPTFTSGKIKTMFFTLCDVG
ERLVKKLEKEVEIADDGILEMKEFSARFTTDVIGSFGFGIEINSLEHPDTEFRVRGSQVF
EKPKYPPIFFQFCVNFKPLARMLKISTTAKEIEEFFTRIVKETIEYREKNQIIRNDFMNL
LIQLKNFGKLEGDITSIGKLTLNEIVAQCFIFFAAGYETSSTTMAYALFELALNQNIQDK
ARDNVRKILSKYDGKFTYEGLMEMDYVDMCVNETLRKYPPVSFITRYCSNDYKIEHTEHV
IKKGQLVIIPTYAIHHDKDIFPNPEVFDPERFSQLESPKIPQVAFMPFGHGARNCIGLRF
GQIQAKVGLAMLLNNFKFELSDKTQNPLKFRKDTIVMLIAEGGIHLKVTKI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g15817.t3 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 1 | 411 | 8.9E-117 |
| 2 | g15817.t3 | PANTHER | PTHR24292 | CYTOCHROME P450 | 2 | 411 | 3.8E-160 |
| 3 | g15817.t3 | PANTHER | PTHR24292:SF95 | CYP6A16, ISOFORM B-RELATED | 2 | 411 | 3.8E-160 |
| 8 | g15817.t3 | PRINTS | PR00463 | E-class P450 group I signature | 204 | 221 | 5.8E-18 |
| 12 | g15817.t3 | PRINTS | PR00385 | P450 superfamily signature | 215 | 232 | 7.0E-12 |
| 4 | g15817.t3 | PRINTS | PR00463 | E-class P450 group I signature | 224 | 250 | 5.8E-18 |
| 11 | g15817.t3 | PRINTS | PR00385 | P450 superfamily signature | 269 | 280 | 7.0E-12 |
| 7 | g15817.t3 | PRINTS | PR00463 | E-class P450 group I signature | 310 | 334 | 5.8E-18 |
| 6 | g15817.t3 | PRINTS | PR00463 | E-class P450 group I signature | 345 | 355 | 5.8E-18 |
| 10 | g15817.t3 | PRINTS | PR00385 | P450 superfamily signature | 346 | 355 | 7.0E-12 |
| 5 | g15817.t3 | PRINTS | PR00463 | E-class P450 group I signature | 355 | 378 | 5.8E-18 |
| 9 | g15817.t3 | PRINTS | PR00385 | P450 superfamily signature | 355 | 366 | 7.0E-12 |
| 1 | g15817.t3 | Pfam | PF00067 | Cytochrome P450 | 10 | 399 | 9.0E-92 |
| 14 | g15817.t3 | ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 348 | 357 | - |
| 13 | g15817.t3 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 3 | 409 | 5.76E-102 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed