General information for g15831.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Mitogen-activated protein kinase kinase kinase 7.
Parent gene
- The parent gene g15831 is located on chr_4: 6960734..6961859 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15831 | g15831.t7 | TTS | g15831.t7 | 6959298 | 6959298 |
| chr_4 | g15831 | g15831.t7 | isoform | g15831.t7 | 6959477 | 6960734 |
| chr_4 | g15831 | g15831.t7 | exon | g15831.t7.exon1 | 6959477 | 6959713 |
| chr_4 | g15831 | g15831.t7 | exon | g15831.t7.exon2 | 6959784 | 6960495 |
| chr_4 | g15831 | g15831.t7 | cds | g15831.t7.CDS1 | 6960109 | 6960474 |
| chr_4 | g15831 | g15831.t7 | exon | g15831.t7.exon3 | 6960568 | 6960734 |
| chr_4 | g15831 | g15831.t7 | TSS | g15831.t7 | NA | NA |
Sequences
>g15831.t7 Gene=g15831 Length=1116
GTTCGCTATCTTTCACGAGTTCAACACCAAAACATAATTGGACTTTATGGAACAGTAATT
AAAGGACCGTTAGTGAGTTTAGTTATGGAATATGCCGAAGGTGGATCACTTTACAATCTT
CTTCACTGTTCAAGAATTGAATACACAGCAAGTCATGCAATGTCTTGGGTGTCGCTTACC
TTCATGCAATGCGTCCAAAGCCTCTAATCCATCGTGATTTGAAGCCACCAAATTTGTTAC
TAGTCAAAAATGGTCTTGTGTTGAAAATTTGTGATTTTGGCACTGTGACTGATAAAAGTA
CATTGATGACAAATAATAAAGGAAGTGCTGCATGGATGGCGCCAGAAGTTTTTGAGGGTT
CAATTTATTCAGAAAGATGCGATGTTTTCAGTTGGAGTATCATTTTATGGGAATGTTTGG
CACGTGAATTGCCTTTTAAAGAAATTGAATTGACTTACTCAATTATGTGGTGTGTTCATA
AAGGTAAACTTGGAAAATTTGTCAAATCAACTTCAAATTTTCAATTTTTCAAAAAAATTT
TGATTTTTTTATGAAAATTGAATTTTTTCGAAACAAAATCGAACACTTTAAATTGTGCAA
ACTTTCTATTTTTTTGATTGTCACTAATTCAAATTTATAACAAACTTTTTAATCACAGGT
CAACGCCCACATAAAATAGAAGGCCTTCCAAAGCCAATAAATCAATTAATGACACAATGT
TGGGATCCTTTACCCCAAAATCGTCCATCAATGGAAGAAGTTCATGAAAGAATGAAAACA
CTTTGTGAATTTTTCCCTGAATGTGAACCACTCAATATGGATGAAACATATGACGATGAA
ACCTCAAATATTGACACATATGATTCCATAATTTGGCCTCACGGACACCAACTGCACAAC
AATATCTTCTTAATGTTTCATCAGTTGATGCAGCACGATGGTCAAGTGGTGATTCTGGTA
ATCCAAAAATTGTCTCATCAACTTTTCACAATGAACCACCTATGGTTAGAAGTGTCAGCA
CTGGCAGTGGCATGATGACACCACTCAATATCGATGTTGATCCAAATGCTTGGGATTTAA
AGAATTACGAACTGCAACGACTCATTGGCGGCAACT
>g15831.t7 Gene=g15831 Length=121
MRPKPLIHRDLKPPNLLLVKNGLVLKICDFGTVTDKSTLMTNNKGSAAWMAPEVFEGSIY
SERCDVFSWSIILWECLARELPFKEIELTYSIMWCVHKGKLGKFVKSTSNFQFFKKILIF
L
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g15831.t7 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 1 | 118 | 8.8E-32 |
| 2 | g15831.t7 | PANTHER | PTHR46716 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 | 1 | 106 | 6.0E-54 |
| 1 | g15831.t7 | Pfam | PF00069 | Protein kinase domain | 6 | 88 | 2.8E-21 |
| 4 | g15831.t7 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 6 | 18 | - |
| 6 | g15831.t7 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 121 | 20.287 |
| 3 | g15831.t7 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 4 | 104 | 7.69E-28 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000287 | magnesium ion binding | MF |
| GO:0004709 | MAP kinase kinase kinase activity | MF |
| GO:0007165 | signal transduction | BP |
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
