General information for g15831.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Mitogen-activated protein kinase kinase kinase 7.
Parent gene
- The parent gene g15831 is located on chr_4: 6960734..6961859 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15831 | g15831.t8 | TTS | g15831.t8 | 6959298 | 6959298 |
| chr_4 | g15831 | g15831.t8 | isoform | g15831.t8 | 6959477 | 6960734 |
| chr_4 | g15831 | g15831.t8 | exon | g15831.t8.exon1 | 6959477 | 6959713 |
| chr_4 | g15831 | g15831.t8 | exon | g15831.t8.exon2 | 6959784 | 6960477 |
| chr_4 | g15831 | g15831.t8 | cds | g15831.t8.CDS1 | 6960109 | 6960477 |
| chr_4 | g15831 | g15831.t8 | exon | g15831.t8.exon3 | 6960549 | 6960734 |
| chr_4 | g15831 | g15831.t8 | cds | g15831.t8.CDS2 | 6960549 | 6960650 |
| chr_4 | g15831 | g15831.t8 | TSS | g15831.t8 | NA | NA |
Sequences
>g15831.t8 Gene=g15831 Length=1117
GTTCGCTATCTTTCACGAGTTCAACACCAAAACATAATTGGACTTTATGGAACAGTAATT
AAAGGACCGTTAGTGAGTTTAGTTATGGAATATGCCGAAGGTGGATCACTTTACAATCTT
CTTCACTGTTCAAGAATTGAATACACAGCAAGTCATGCAATGTCTTGGTGTCGACAAACT
GCTGATGCAATGCGTCCAAAGCCTCTAATCCATCGTGATTTGAAGCCACCAAATTTGTTA
CTAGTCAAAAATGGTCTTGTGTTGAAAATTTGTGATTTTGGCACTGTGACTGATAAAAGT
ACATTGATGACAAATAATAAAGGAAGTGCTGCATGGATGGCGCCAGAAGTTTTTGAGGGT
TCAATTTATTCAGAAAGATGCGATGTTTTCAGTTGGAGTATCATTTTATGGGAATGTTTG
GCACGTGAATTGCCTTTTAAAGAAATTGAATTGACTTACTCAATTATGTGGTGTGTTCAT
AAAGGTAAACTTGGAAAATTTGTCAAATCAACTTCAAATTTTCAATTTTTCAAAAAAATT
TTGATTTTTTTATGAAAATTGAATTTTTTCGAAACAAAATCGAACACTTTAAATTGTGCA
AACTTTCTATTTTTTTGATTGTCACTAATTCAAATTTATAACAAACTTTTTAATCACAGG
TCAACGCCCACATAAAATAGAAGGCCTTCCAAAGCCAATAAATCAATTAATGACACAATG
TTGGGATCCTTTACCCCAAAATCGTCCATCAATGGAAGAAGTTCATGAAAGAATGAAAAC
ACTTTGTGAATTTTTCCCTGAATGTGAACCACTCAATATGGATGAAACATATGACGATGA
AACCTCAAATATTGACACATATGATTCCATAATTTGGCCTCACGGACACCAACTGCACAA
CAATATCTTCTTAATGTTTCATCAGTTGATGCAGCACGATGGTCAAGTGGTGATTCTGGT
AATCCAAAAATTGTCTCATCAACTTTTCACAATGAACCACCTATGGTTAGAAGTGTCAGC
ACTGGCAGTGGCATGATGACACCACTCAATATCGATGTTGATCCAAATGCTTGGGATTTA
AAGAATTACGAACTGCAACGACTCATTGGCGGCAACT
>g15831.t8 Gene=g15831 Length=156
MEYAEGGSLYNLLHCSRIEYTASHAMSWCRQTADAMRPKPLIHRDLKPPNLLLVKNGLVL
KICDFGTVTDKSTLMTNNKGSAAWMAPEVFEGSIYSERCDVFSWSIILWECLARELPFKE
IELTYSIMWCVHKGKLGKFVKSTSNFQFFKKILIFL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g15831.t8 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 6 | 153 | 2.1E-35 |
| 2 | g15831.t8 | PANTHER | PTHR46716 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 | 1 | 141 | 1.9E-70 |
| 1 | g15831.t8 | Pfam | PF00069 | Protein kinase domain | 1 | 122 | 1.2E-25 |
| 5 | g15831.t8 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 41 | 53 | - |
| 7 | g15831.t8 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 156 | 21.234 |
| 4 | g15831.t8 | SMART | SM00220 | serkin_6 | 1 | 156 | 1.3E-6 |
| 3 | g15831.t8 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 139 | 6.61E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000287 | magnesium ion binding | MF |
| GO:0004709 | MAP kinase kinase kinase activity | MF |
| GO:0007165 | signal transduction | BP |
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
