General information for g15894.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Leukotriene A-4 hydrolase.
Parent gene
- The parent gene g15894 is located on chr_4: 7201690..7203778 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15894 | g15894.t8 | isoform | g15894.t8 | 7201690 | 7203764 |
| chr_4 | g15894 | g15894.t8 | exon | g15894.t8.exon1 | 7201690 | 7202292 |
| chr_4 | g15894 | g15894.t8 | cds | g15894.t8.CDS1 | 7201690 | 7202292 |
| chr_4 | g15894 | g15894.t8 | exon | g15894.t8.exon2 | 7202348 | 7202515 |
| chr_4 | g15894 | g15894.t8 | cds | g15894.t8.CDS2 | 7202348 | 7202506 |
| chr_4 | g15894 | g15894.t8 | exon | g15894.t8.exon3 | 7203490 | 7203764 |
| chr_4 | g15894 | g15894.t8 | TSS | g15894.t8 | 7203793 | 7203793 |
| chr_4 | g15894 | g15894.t8 | TTS | g15894.t8 | NA | NA |
Sequences
>g15894.t8 Gene=g15894 Length=1046
TGAGAATAAATTTTTGGATTAAATTTATAAAAAGGTTTTTGAAATGTTGAAAATGATTAA
AAAATAATTTAAAAGAAACCTTTGTACTTATGTGTTTTAAAAAGATGATTTTATAAGCCG
GTTTTTAACATATGGTTATAAATTTATTTAAATTAATAGAAATTTAACAAAATATAATCA
AAATTTGTTAATAAAATTAGCCAAATGCAAAAACATATAAAATTCATGGATTATATTGGA
CAATTACCAAATATTTCTAAAGAATATTGTAGAAGACTTCAAACATGCCACGTCTTGGAA
CAGATCCATCATCTTATTCTCAACCTGATCTTGTAAAGATCAAACATATTGATTTGGACT
GGACTGTTGATTTTAGTCAGAAAATTATCAGTGGAAGTGCTCAAATTCAATTCATCATTT
TAACGAAATTCATTGAGGAAATTCTTCTTGATGTCAGTGATATAACAATTGATTCTGTTA
ATGTTCTCAATGAAGGCTGTGAAATTCCTTTGAAATTTGATATTTCTGGATTGGTTCCTG
ATATTGGTTCAAAACTTACAATTACTTTGCCAACAAAAACTGATGGCAAATTGACCTTGA
AAATTTACTACAAAACATCCAGCAGTGCAAGCGCTTTACAATGGCTCACACCTGAACAAA
CTCTTGGCAAAAAACATCCATTCATGTTCAGTCAATGTCAAGCAATTCATGCTCGAAGTA
TTCTTCCATGTCAAGACTCACCATCAGTTAAATTCACTTACAATGCGACACTTAGACATT
CACCAGAATTGACTGGTTTAATGAGTGCAATTCGTCAAGGAAGTGAAAATGGTGTAACCA
AATATGTGCAAAAAGTTCCAATTCCAAGTTATTTGCTTGCTATTGCAGTTGGTGATTTGT
ATTCGAAAAAAATTGGACCAAGATCACATGTATGGGCTGAAAAAGACATTGTTGATGAAG
CTGCTGAGGAATATAGTGACACTGAAAAGTTTTTGAAAACAGCTGAAGATATTTGCGGAC
CTTATTTATGGCAGCAATATGATTTG
>g15894.t8 Gene=g15894 Length=254
MPRLGTDPSSYSQPDLVKIKHIDLDWTVDFSQKIISGSAQIQFIILTKFIEEILLDVSDI
TIDSVNVLNEGCEIPLKFDISGLVPDIGSKLTITLPTKTDGKLTLKIYYKTSSSASALQW
LTPEQTLGKKHPFMFSQCQAIHARSILPCQDSPSVKFTYNATLRHSPELTGLMSAIRQGS
ENGVTKYVQKVPIPSYLLAIAVGDLYSKKIGPRSHVWAEKDIVDEAAEEYSDTEKFLKTA
EDICGPYLWQQYDL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g15894.t8 | Gene3D | G3DSA:2.60.40.1730 | tricorn interacting facor f3 domain | 16 | 203 | 0.0e+00 |
| 8 | g15894.t8 | Gene3D | G3DSA:1.10.1740.60 | - | 204 | 254 | 0.0e+00 |
| 2 | g15894.t8 | PANTHER | PTHR45726 | - | 6 | 254 | 0.0e+00 |
| 3 | g15894.t8 | PANTHER | PTHR45726:SF3 | LEUKOTRIENE A-4 HYDROLASE | 6 | 254 | 0.0e+00 |
| 4 | g15894.t8 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 144 | 159 | 7.8e-05 |
| 5 | g15894.t8 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 187 | 202 | 7.8e-05 |
| 1 | g15894.t8 | Pfam | PF17900 | Peptidase M1 N-terminal domain | 21 | 197 | 0.0e+00 |
| 6 | g15894.t8 | SUPERFAMILY | SSF63737 | Leukotriene A4 hydrolase N-terminal domain | 4 | 204 | 0.0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
