General information for g159.t63
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Guanosine-3’,5’-bis(diphosphate) 3’-pyrophosphohydrolase MESH1.
Parent gene
- The parent gene g159 is located on chr_3: 1438731..1441999 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g159 | g159.t63 | TTS | g159.t63 | 1438702 | 1438702 |
| chr_3 | g159 | g159.t63 | isoform | g159.t63 | 1438731 | 1441778 |
| chr_3 | g159 | g159.t63 | exon | g159.t63.exon1 | 1438731 | 1439277 |
| chr_3 | g159 | g159.t63 | cds | g159.t63.CDS1 | 1438731 | 1439270 |
| chr_3 | g159 | g159.t63 | exon | g159.t63.exon2 | 1441777 | 1441778 |
| chr_3 | g159 | g159.t63 | TSS | g159.t63 | 1441999 | 1441999 |
Sequences
>g159.t63 Gene=g159 Length=549
CGTTGTAAAATGGATAATGAAGCAATAAAAAAATACACAAAGTGCATGAATTTTGCTGCA
AAAAAGCATTCTACACAACGTCGTAAAGATTCAGAGGAAACTCCTTATATCAATCATCCT
ATTGGAGTAGCAAATATTATTGCAAATGAAGGAGATGTAACTGATTTAGATGTCTTGATG
GCTGCTTTATTGCATGACACTGTTGAAGACACTGATTGTTCATTTGATGAGATTGAAGAA
CATTTTGGTGCTGACGTTTGTAACATTGTTAAAGAAGTTACTGATGACAAGTCATTGCCA
AAAATGGAAAGAAAAAGACTACAAATTGAACATGCAAAAACTTCAAGCTCGAAAGCAAAA
TTAGTAAAATTGGCTGATAAACTTTATAATTTGAGAGATTTACAAAGAGAAATGCCAATT
GGATGGACTAAAGAACGAGTAGATGAATATTTCATATGGGCTAAAAAAGTTGTCGATAAT
CTTAGAGGAACTAATTTGAAACTTGAAACAAAACTTGATGAAATATTTTGTGCTCAAGGA
TTAAAGTGA
>g159.t63 Gene=g159 Length=179
MDNEAIKKYTKCMNFAAKKHSTQRRKDSEETPYINHPIGVANIIANEGDVTDLDVLMAAL
LHDTVEDTDCSFDEIEEHFGADVCNIVKEVTDDKSLPKMERKRLQIEHAKTSSSKAKLVK
LADKLYNLRDLQREMPIGWTKERVDEYFIWAKKVVDNLRGTNLKLETKLDEIFCAQGLK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g159.t63 | CDD | cd00077 | HDc | 32 | 148 | 0.0000001 |
| 5 | g159.t63 | Gene3D | G3DSA:1.10.3210.10 | Hypothetical protein af1432 | 2 | 179 | 0.0000000 |
| 2 | g159.t63 | PANTHER | PTHR46246 | GUANOSINE-3’,5’-BIS(DIPHOSPHATE) 3’-PYROPHOSPHOHYDROLASE MESH1 | 2 | 177 | 0.0000000 |
| 1 | g159.t63 | Pfam | PF13328 | HD domain | 13 | 134 | 0.0000000 |
| 6 | g159.t63 | ProSiteProfiles | PS51831 | HD domain profile. | 33 | 128 | 15.1850000 |
| 4 | g159.t63 | SMART | SM00471 | hd_13 | 29 | 137 | 0.0012000 |
| 3 | g159.t63 | SUPERFAMILY | SSF109604 | HD-domain/PDEase-like | 2 | 174 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K21138 (guanosine-3’,5’-bis(diphosphate) 3’-pyrophosphohydrolase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
