General information for g15994.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Cystinosin-like protein.
Parent gene
- The parent gene g15994 is located on chr_4: 7739132..7740230 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15994 | g15994.t1 | isoform | g15994.t1 | 7739132 | 7740230 |
| chr_4 | g15994 | g15994.t1 | exon | g15994.t1.exon1 | 7739132 | 7739197 |
| chr_4 | g15994 | g15994.t1 | cds | g15994.t1.CDS1 | 7739132 | 7739197 |
| chr_4 | g15994 | g15994.t1 | exon | g15994.t1.exon2 | 7739252 | 7739446 |
| chr_4 | g15994 | g15994.t1 | cds | g15994.t1.CDS2 | 7739252 | 7739446 |
| chr_4 | g15994 | g15994.t1 | exon | g15994.t1.exon3 | 7739498 | 7740035 |
| chr_4 | g15994 | g15994.t1 | cds | g15994.t1.CDS3 | 7739498 | 7740035 |
| chr_4 | g15994 | g15994.t1 | exon | g15994.t1.exon4 | 7740094 | 7740230 |
| chr_4 | g15994 | g15994.t1 | cds | g15994.t1.CDS4 | 7740094 | 7740230 |
| chr_4 | g15994 | g15994.t1 | TSS | g15994.t1 | NA | NA |
| chr_4 | g15994 | g15994.t1 | TTS | g15994.t1 | NA | NA |
Sequences
>g15994.t1 Gene=g15994 Length=936
ATGAAGTTTACAGTTCTGCTTTTGAGTTTTATATTTTTACAACAAACAAAGGGCGATGGT
TTGCATTCATTTCAATTATCTTCAACTGAATTAAATTTAATAGCAGGAGAAAAAGCTGAA
ATTATTTTTACATCATTTTTAAACTCTTCAAATCCAACAACTGTAAATTTAATAAAAAAT
CGTCATGGAATTATCAAGTTAAAACCAAAAACTTTCATAATTCCACCAGAAATGAATTTT
TTTAATCAAACAATTCAAATTACTTCGTTAAAATCAGGAAAAGTTGAAATTGAAGGACAC
ACAGATTCAAATCCAGATGCAATTATTTTCTTTAGAATAATCGTAGCAAAATCAAATTTC
CTTATTATAATAGCATCAGTTGTTGGTTGGATTTATTTTATTGCTTGGAGTTTATCACTT
TATCCTCAAATTTGGATGATAATTCAAATGAAATCAGTCACTGGTTTGAGCTTTGATTAT
TTGTCTCTTAGTTTTTTCGGGCATTTACTTTATGCTGTTTTTAATTTGGCTTTATATTTT
GGAAAATATTTTCAAGATGAATATTTTCGAAGACATCCACATGGATTGAATCCAGTTGAA
TTAAATGATGTTTTTTATTGCATCCACGTGTTGGCTTTATCATTAATAACTGTAATTTGC
TGTTTCATATTTCAACGTGATAATCAAAAAATTACAAAATATGCTTGGTCAATAAACGGA
ACTTTTATATTTTCATTGATAATTGTTGCAATTTTGTGTTCATTTGGAAAGCTTCATTGG
TTTGATTTGATTAATACTTGCAATCTTATAAAAGTTATTGGAAGTTTAATTAAATATGTG
CCACAAGTTTATTTTAATCATAAAAGAAAGAATTTAGAAAATCAAGGAGTGACAACTTAT
CAAAATAACAAAGAATCCATCAAATTAACAAATTAA
>g15994.t1 Gene=g15994 Length=311
MKFTVLLLSFIFLQQTKGDGLHSFQLSSTELNLIAGEKAEIIFTSFLNSSNPTTVNLIKN
RHGIIKLKPKTFIIPPEMNFFNQTIQITSLKSGKVEIEGHTDSNPDAIIFFRIIVAKSNF
LIIIASVVGWIYFIAWSLSLYPQIWMIIQMKSVTGLSFDYLSLSFFGHLLYAVFNLALYF
GKYFQDEYFRRHPHGLNPVELNDVFYCIHVLALSLITVICCFIFQRDNQKITKYAWSING
TFIFSLIIVAILCSFGKLHWFDLINTCNLIKVIGSLIKYVPQVYFNHKRKNLENQGVTTY
QNNKESIKLTN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 3 | g15994.t1 | PANTHER | PTHR13131 | CYSTINOSIN | 116 | 293 | 5.3E-54 |
| 4 | g15994.t1 | PANTHER | PTHR13131:SF5 | CYSTINOSIN | 116 | 293 | 5.3E-54 |
| 2 | g15994.t1 | Pfam | PF04193 | PQ loop repeat | 124 | 180 | 4.8E-14 |
| 1 | g15994.t1 | Pfam | PF04193 | PQ loop repeat | 264 | 293 | 7.2E-6 |
| 17 | g15994.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 18 | g15994.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 19 | g15994.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 13 | - |
| 25 | g15994.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 14 | g15994.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 119 | - |
| 20 | g15994.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 120 | 141 | - |
| 11 | g15994.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 142 | 160 | - |
| 23 | g15994.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 161 | 184 | - |
| 15 | g15994.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 185 | 203 | - |
| 22 | g15994.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 204 | 224 | - |
| 12 | g15994.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 225 | 235 | - |
| 24 | g15994.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 236 | 257 | - |
| 16 | g15994.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 258 | 262 | - |
| 21 | g15994.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 263 | 280 | - |
| 13 | g15994.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 281 | 311 | - |
| 9 | g15994.t1 | SMART | SM00679 | ctns | 138 | 169 | 6.2E-4 |
| 10 | g15994.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 8 | g15994.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 118 | 140 | - |
| 7 | g15994.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 161 | 180 | - |
| 6 | g15994.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 205 | 224 | - |
| 5 | g15994.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 236 | 258 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed