General information for g16088.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable low-specificity L-threonine aldolase 2.
Parent gene
- The parent gene g16088 is located on chr_4: 8103365..8104037 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16088 | g16088.t1 | TSS | g16088.t1 | 8102255 | 8102255 |
| chr_4 | g16088 | g16088.t1 | isoform | g16088.t1 | 8102310 | 8104037 |
| chr_4 | g16088 | g16088.t1 | exon | g16088.t1.exon1 | 8102310 | 8102387 |
| chr_4 | g16088 | g16088.t1 | cds | g16088.t1.CDS1 | 8102310 | 8102387 |
| chr_4 | g16088 | g16088.t1 | exon | g16088.t1.exon2 | 8102570 | 8102738 |
| chr_4 | g16088 | g16088.t1 | cds | g16088.t1.CDS2 | 8102570 | 8102738 |
| chr_4 | g16088 | g16088.t1 | exon | g16088.t1.exon3 | 8102800 | 8102831 |
| chr_4 | g16088 | g16088.t1 | cds | g16088.t1.CDS3 | 8102800 | 8102831 |
| chr_4 | g16088 | g16088.t1 | exon | g16088.t1.exon4 | 8103033 | 8103234 |
| chr_4 | g16088 | g16088.t1 | cds | g16088.t1.CDS4 | 8103033 | 8103234 |
| chr_4 | g16088 | g16088.t1 | exon | g16088.t1.exon5 | 8103361 | 8104037 |
| chr_4 | g16088 | g16088.t1 | cds | g16088.t1.CDS5 | 8103361 | 8104037 |
| chr_4 | g16088 | g16088.t1 | TTS | g16088.t1 | 8104105 | 8104105 |
Sequences
>g16088.t1 Gene=g16088 Length=1158
ATGTCAATTTATCGCAGAGTTTTTGATGATGCTTCTTTAAAAAACTATAGAATTGTCGAT
TTAAGAAGTGATACTTTATCAGTTCCAACAGATGAAATGAGAAAAGCAATGTTTGAATCT
GAAATTGGTGATGATGTTTATGGTGAAGATCCAACTGTTAATAAACTTGAAGTTAAAGTC
GCTGAATTATTAGGAAAAGAAGCTGCAGTTTTTGTTCCATCTGGAACTATGGGAAATTTG
CTTGCAATCATGGTCCATTGTGATAAGCGAGGCTCTGAGGTCATGTGCGGCAGTCTTAGT
CATGTCTTTTGTTATGAACAAGGTTCAGCTTCATCACTTGCTGGAGTTTTTGTTCATAAA
TTGGAAAACAATGAAGATGGAACATTTTCAATTGAAGCAGTGAAAAAATTAGCCAGAGGT
TCTGATATTCATGAACCAGTAACTCAATTAGTTGTTGTTGAGAATACACACAATATGGCA
GGTGGAAAAGTTTTGCCATTAAACTGGATTGAAGAATTGTCAAAAGTTTGCAAAGATAAA
AACCTAAAACTTCACATGGATGGAGCTCGTGTTTTTAGTGCAGCTGAATATCTTAAAGTT
CCAGTTTCTCGTGTAGTTCGTGATGTTGATTCAATATCATTTTGTTTGAGTAAAAATCTT
TGCTGTCCTGTTGGTTCATTGCTTGTTGGCAAAAAAGAATTTGTTGAACAAGCAAGAAGA
TTTCGAAAAGCACTTGGTGGTGGAATGAGACAAGTTGGATTTTTGGCAGCTGCTGGAATG
TTTGCTCTTGATAATATTGTGCCGAAATTGAAATTTGATCATGAACATGCAAAACAACTT
GCTGCTGCTGTTGATGAGCTTAAAAGTAAAATTTTCTATGTTGACGTCAAAAATTTACAT
AGCAATATTTTGATGATAAAAGTTGCTGATAATGATAAAAACATTACAGCTTTAGATTTG
AGTAATCGTTTGGTAGAAGTAAAAGATGAAGAAATTGAAAATGGAATATGTGATGAACAG
AAGAAAGGAATAATTGTCAAATCAAGCTGCAAAAATTTGCAAACATTGCGTGTTGTTTTT
TATCATCAAATTACTGATGAAATGACAAATTTATTAGTCAAAAAAGTTTCATACGTCATT
AAGGAATTTGAAAAGTGA
>g16088.t1 Gene=g16088 Length=385
MSIYRRVFDDASLKNYRIVDLRSDTLSVPTDEMRKAMFESEIGDDVYGEDPTVNKLEVKV
AELLGKEAAVFVPSGTMGNLLAIMVHCDKRGSEVMCGSLSHVFCYEQGSASSLAGVFVHK
LENNEDGTFSIEAVKKLARGSDIHEPVTQLVVVENTHNMAGGKVLPLNWIEELSKVCKDK
NLKLHMDGARVFSAAEYLKVPVSRVVRDVDSISFCLSKNLCCPVGSLLVGKKEFVEQARR
FRKALGGGMRQVGFLAAAGMFALDNIVPKLKFDHEHAKQLAAAVDELKSKIFYVDVKNLH
SNILMIKVADNDKNITALDLSNRLVEVKDEEIENGICDEQKKGIIVKSSCKNLQTLRVVF
YHQITDEMTNLLVKKVSYVIKEFEK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g16088.t1 | CDD | cd06502 | TA_like | 20 | 379 | 0e+00 |
| 6 | g16088.t1 | Gene3D | G3DSA:3.40.640.10 | - | 14 | 265 | 0e+00 |
| 5 | g16088.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 266 | 381 | 1e-07 |
| 2 | g16088.t1 | PANTHER | PTHR48097:SF9 | L-THREONINE ALDOLASE | 14 | 384 | 0e+00 |
| 3 | g16088.t1 | PANTHER | PTHR48097 | L-THREONINE ALDOLASE-RELATED | 14 | 384 | 0e+00 |
| 7 | g16088.t1 | PIRSF | PIRSF017617 | Thr_aldolase | 11 | 385 | 0e+00 |
| 1 | g16088.t1 | Pfam | PF01212 | Beta-eliminating lyase | 20 | 300 | 0e+00 |
| 4 | g16088.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 19 | 381 | 0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016829 | lyase activity | MF |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01620 (threonine aldolase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
