General information for g16094.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldehyde dehydrogenase, dimeric NADP-preferring.
Parent gene
- The parent gene g16094 is located on chr_4: 8135015..8141389 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16094 | g16094.t2 | isoform | g16094.t2 | 8129359 | 8133642 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon1 | 8129359 | 8129483 |
| chr_4 | g16094 | g16094.t2 | TSS | g16094.t2 | 8129395 | 8129395 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon2 | 8132277 | 8132468 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS1 | 8132314 | 8132468 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon3 | 8132561 | 8132736 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS2 | 8132561 | 8132736 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon4 | 8132864 | 8133009 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS3 | 8132864 | 8133009 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon5 | 8133065 | 8133146 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS4 | 8133065 | 8133146 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon6 | 8133201 | 8133272 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS5 | 8133201 | 8133272 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon7 | 8133334 | 8133357 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS6 | 8133334 | 8133357 |
| chr_4 | g16094 | g16094.t2 | exon | g16094.t2.exon8 | 8133427 | 8133642 |
| chr_4 | g16094 | g16094.t2 | cds | g16094.t2.CDS7 | 8133427 | 8133641 |
| chr_4 | g16094 | g16094.t2 | TTS | g16094.t2 | NA | NA |
Sequences
>g16094.t2 Gene=g16094 Length=1033
ATAACAAAAATCATATGTTCATGAATGAAATGCGTAAAATTTTCTCTATCGATTTTCTCA
ATGAAAGTGAAATTGAAAATAAAATTTTAAATTTATTTCGTGTTCTTAAAACTCAATCTA
GTCAGTTAAAGTACAGCTAATTGAACCAAAAAAAAAAGAAACATGACATACGAGGACTTG
ATGAGTCGTGCCGCAACGGCATTTCAAAGCGGCAAAACCAAAGATATTGATTTTAGAAGG
AAACAGTTGAACGCATTGTTGCGAATGTATGAAGAGAATAAAGATGAAATGGCACGCGTT
TTGGCTGCTGATTTGAGACGACCAAAGCAAGAATCCTACATTCTTGAAATTGAATTCCTT
ATAAATGACATCATCACAACAATCAACAGTCTCGATGAATGGACGAAGCCAATGAAACCT
GAAAAAGGAATTGTCAATATGATGGATGATGTTTTGATTTATCCTGATCCTCTTGGTGTT
GTTCTAGTCATGGGTGCATGGAATTATCCACTTCAACTCCCACTTGTTCCTTTTGGTGCT
GCAATTGCAGCTGGAAATGTTGCCATATTAAAACCTAGTGAAATTTCAGTCAATTGTGCA
AATTTCATTGCTGAAAATATTCCTAAATATTTGGATAATGAATGTTATCATGTTGTATGT
GGTGGAGTTCAAGAAACTACTGAACTTTTGAAGCATAAATTTGATTATATTTTTTATACT
GGCTCTGGACGTGTTGGAAAAATTGTTTATGAAGCAGCAGCAAAACATTTAACACCGGTG
ACATTAGAATTGGGAGGAAAGTCACCTTGCTATATTGATAACACAGTTGACATTTCAAAA
GCAACACGACGAGTTTTATGGGGAAAATTTATTAATGCTGGTCAAACATGCATTGCACCT
GATTATATTTTGTGTACCAAAGAAATTCAAGATAAGTTTGTTAAAGAGGCTAAAGTTGTA
CTTAAAGAATGGTATGGTGATGACATCAAAAAAAGTCCCGACTTTTGTAGAATTGTAAAT
CAAGTTAATTTTC
>g16094.t2 Gene=g16094 Length=290
MTYEDLMSRAATAFQSGKTKDIDFRRKQLNALLRMYEENKDEMARVLAADLRRPKQESYI
LEIEFLINDIITTINSLDEWTKPMKPEKGIVNMMDDVLIYPDPLGVVLVMGAWNYPLQLP
LVPFGAAIAAGNVAILKPSEISVNCANFIAENIPKYLDNECYHVVCGGVQETTELLKHKF
DYIFYTGSGRVGKIVYEAAAKHLTPVTLELGGKSPCYIDNTVDISKATRRVLWGKFINAG
QTCIAPDYILCTKEIQDKFVKEAKVVLKEWYGDDIKKSPDFCRIVNQVNF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g16094.t2 | Coils | Coil | Coil | 26 | 46 | - |
| 7 | g16094.t2 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 2 | 211 | 1.2E-54 |
| 8 | g16094.t2 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 212 | 290 | 6.1E-22 |
| 2 | g16094.t2 | PANTHER | PTHR43570:SF29 | ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q | 4 | 290 | 3.4E-145 |
| 3 | g16094.t2 | PANTHER | PTHR43570 | ALDEHYDE DEHYDROGENASE | 4 | 290 | 3.4E-145 |
| 1 | g16094.t2 | Pfam | PF00171 | Aldehyde dehydrogenase family | 3 | 282 | 3.7E-52 |
| 6 | g16094.t2 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 208 | 215 | - |
| 5 | g16094.t2 | ProSitePatterns | PS00070 | Aldehyde dehydrogenases cysteine active site. | 236 | 247 | - |
| 4 | g16094.t2 | SUPERFAMILY | SSF53720 | ALDH-like | 5 | 287 | 6.68E-75 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
