General information for g16121.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione S-transferase theta-1.
Parent gene
- The parent gene g16121 is located on chr_4: 8241974..8242693 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16121 | g16121.t1 | TSS | g16121.t1 | 8241904 | 8241904 |
| chr_4 | g16121 | g16121.t1 | isoform | g16121.t1 | 8241974 | 8242693 |
| chr_4 | g16121 | g16121.t1 | exon | g16121.t1.exon1 | 8241974 | 8242185 |
| chr_4 | g16121 | g16121.t1 | cds | g16121.t1.CDS1 | 8241974 | 8242185 |
| chr_4 | g16121 | g16121.t1 | exon | g16121.t1.exon2 | 8242234 | 8242693 |
| chr_4 | g16121 | g16121.t1 | cds | g16121.t1.CDS2 | 8242234 | 8242693 |
| chr_4 | g16121 | g16121.t1 | TTS | g16121.t1 | 8243703 | 8243703 |
Sequences
>g16121.t1 Gene=g16121 Length=672
ATGAAATTTTATTATCATTTACTTTCACAACCATCAAGAGCTCTTTACATCTTTCTGAAA
CTCAATAATATCACAGCAGAATTTATTATAATCGATTTCCCCAATGGTGATCATTTAACA
GATGAATTTAAAGAAATTAATCGCTTCCAAAAAGTTCCTTGCATTGTTGATGATGATGGA
TGGAAATTAGCTGAAAGTATTGCAATTTTAAGATATTTAATGTCAAAATACAAAAATATT
CCTGATCATTTTTATCCATCTGATATAAGAGCAAGAGCAGCAGTTGATGAATATCTTGAA
TGGCAACACATAAATACTCGATTTGGTTGCGGAGTATATTTTCAGTTAAGGAAGAAAATT
GGACCATTCGCGGTTCTTTCAGAAGAAGCACTTCCAATTTTTAAATTTCTTATGGAATCA
ACTTTAGAAGCAATTGAAACTTTGTGGTTGAGAGGAAAGAAATTTTTATGTTCTGATGAA
ATTTCTTTTGCTGATATAATTGCTGCTTGTGAAATTGAACAAGCTCGTATGACGGGTTAT
GATTTATTCGAAAATCGACCTAGATTAAAAGAATGGTATGAAAAAGTTAAGGAGACAACA
AATCCTTATTATGATGAAGCTCATGTGATTGTTAATAAAATTGTAGCAAGAAGTCAAAAA
GCAAAGCTTTAA
>g16121.t1 Gene=g16121 Length=223
MKFYYHLLSQPSRALYIFLKLNNITAEFIIIDFPNGDHLTDEFKEINRFQKVPCIVDDDG
WKLAESIAILRYLMSKYKNIPDHFYPSDIRARAAVDEYLEWQHINTRFGCGVYFQLRKKI
GPFAVLSEEALPIFKFLMESTLEAIETLWLRGKKFLCSDEISFADIIAACEIEQARMTGY
DLFENRPRLKEWYEKVKETTNPYYDEAHVIVNKIVARSQKAKL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g16121.t1 | CDD | cd03050 | GST_N_Theta | 2 | 77 | 0.0000000 |
| 11 | g16121.t1 | CDD | cd03183 | GST_C_Theta | 91 | 214 | 0.0000000 |
| 7 | g16121.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 79 | 0.0000000 |
| 6 | g16121.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 81 | 222 | 0.0000000 |
| 3 | g16121.t1 | PANTHER | PTHR43917 | - | 2 | 221 | 0.0000000 |
| 2 | g16121.t1 | Pfam | PF02798 | Glutathione S-transferase, N-terminal domain | 4 | 73 | 0.0000000 |
| 1 | g16121.t1 | Pfam | PF00043 | Glutathione S-transferase, C-terminal domain | 149 | 196 | 0.0000001 |
| 9 | g16121.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 1 | 81 | 21.0580000 |
| 8 | g16121.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 88 | 223 | 13.1890000 |
| 12 | g16121.t1 | SFLD | SFLDG00358 | Main (cytGST) | 1 | 198 | 0.0000000 |
| 13 | g16121.t1 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 1 | 198 | 0.0000000 |
| 4 | g16121.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 1 | 92 | 0.0000000 |
| 5 | g16121.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 82 | 199 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00799 (glutathione S-transferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
