Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Cofilin/actin-depolymerizing factor-like protein.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g16136 g16136.t16 TTS g16136.t16 8338183 8338183
chr_4 g16136 g16136.t16 isoform g16136.t16 8338443 8342707
chr_4 g16136 g16136.t16 exon g16136.t16.exon1 8338443 8338589
chr_4 g16136 g16136.t16 cds g16136.t16.CDS1 8338547 8338589
chr_4 g16136 g16136.t16 exon g16136.t16.exon2 8338676 8338947
chr_4 g16136 g16136.t16 cds g16136.t16.CDS2 8338676 8338947
chr_4 g16136 g16136.t16 exon g16136.t16.exon3 8342705 8342707
chr_4 g16136 g16136.t16 cds g16136.t16.CDS3 8342705 8342707
chr_4 g16136 g16136.t16 TSS g16136.t16 8342954 8342954

Sequences

>g16136.t16 Gene=g16136 Length=422
ATGGCTTCCGGAGTAACTGTCTCAGATGTTTGTAAGACAACATATGAAGAAATTAAGAAG
GACAAAAAACATCGCTATGTAATTTTTTACATTCGTGATGAGAAGCAAATTGATGTGGAA
GTGATTGGTGAACGTAATGCAGAATATGATTCGTTCCTTGAAGATATTCAAAAAGGCGGT
CCAGGTGAATGCCGATATGGACTCTTTGATTTTGAGTATATGCATCAATGTCAAGGCACC
TCTGAGAGTTCCAAGAAGCAAAAATTATTTTTAATGTCAAGAAGAAGATGTTGTACTCAA
GCTCATTTGATGCATTGAAAAAGTCACTTGTAGGTGTGCAAAAATACATTCAAGCTACAG
ACTTATCAGAGGCCTCACGTGAAGCTGTTGAAGAAAAATTGCGCTCTACTGATCGCAACT
AA

>g16136.t16 Gene=g16136 Length=105
MASGVTVSDVCKTTYEEIKKDKKHRYVIFYIRDEKQIDVEVIGERNAEYDSFLEDIQKGG
PGECRYGLFDFEYMHQCQGTSESSKKQKLFLMSRRRCCTQAHLMH

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g16136.t16 Gene3D G3DSA:3.40.20.10 Severin 1 98 0.0000
2 g16136.t16 PANTHER PTHR11913:SF12 COFILIN/ACTIN-DEPOLYMERIZING FACTOR HOMOLOG-RELATED 2 93 0.0000
3 g16136.t16 PANTHER PTHR11913 COFILIN-RELATED 2 93 0.0000
1 g16136.t16 Pfam PF00241 Cofilin/tropomyosin-type actin-binding protein 11 91 0.0000
7 g16136.t16 ProSiteProfiles PS51263 ADF-H domain profile. 4 105 11.8840
5 g16136.t16 SMART SM00102 adf_2 9 104 0.0015
4 g16136.t16 SUPERFAMILY SSF55753 Actin depolymerizing proteins 1 92 0.0000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003779 actin binding MF
GO:0015629 actin cytoskeleton CC
GO:0030042 actin filament depolymerization BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed