Gene loci information

Transcript annotation

  • This transcript has been annotated as Glutathione S-transferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g16422 g16422.t3 TSS g16422.t3 9399852 9399852
chr_4 g16422 g16422.t3 isoform g16422.t3 9399919 9402902
chr_4 g16422 g16422.t3 exon g16422.t3.exon1 9399919 9400048
chr_4 g16422 g16422.t3 cds g16422.t3.CDS1 9399919 9400048
chr_4 g16422 g16422.t3 exon g16422.t3.exon2 9402340 9402507
chr_4 g16422 g16422.t3 cds g16422.t3.CDS2 9402340 9402507
chr_4 g16422 g16422.t3 exon g16422.t3.exon3 9402601 9402902
chr_4 g16422 g16422.t3 cds g16422.t3.CDS3 9402601 9402902
chr_4 g16422 g16422.t3 TTS g16422.t3 9402941 9402941

Sequences

>g16422.t3 Gene=g16422 Length=600
ATGACTTACAAACTTTATTATTTTAACATTCGAGGTTTGGCTGAGCCAATCCGCTATTTA
TTGAAATATGGTAAAATTGACTTTGAAGATGTGAGAGTTGAAAGAGAAGATTGGCCAAAA
CTCAAAGAAACAATGCCAATGAAACAAATGCCAGTTCTTGAAATTGATGGCAAAAGAGTC
TACCAATCAGTTTCAATTGCTCGCTTCTTAGGCAAGAAAGTCGGACTAGCTGGCAGCAAT
GATTTAGAGAATCTTGAAATTGATAGTGCTGTTGACACTTTTGTTGATTTGAGATTGATA
ATGACAACACCAGAAGATAAAAAAGCAGAAGCCATGAAAACACTCAAAGAAGAAACAGTT
CCATTTTTCTTATCAAAACTCAATGCATTAGCTGAAGAAAACAATGGACATTTGGCATGC
AAGAAACTCACTTGGGCTGATCTCTACTTTGCAGCACTCACTGGAATTGTTAAGTTTGGT
GCAATTGAAGGTGAAGATATTTGGGAAAAATATCCAGCATTGAGAAAAGTTGTTGATAAT
GTAGAGGCAATTGATGCAATTAAAACATGGATTAATGAACGACCTGTTACTGATTTTTAA

>g16422.t3 Gene=g16422 Length=199
MTYKLYYFNIRGLAEPIRYLLKYGKIDFEDVRVEREDWPKLKETMPMKQMPVLEIDGKRV
YQSVSIARFLGKKVGLAGSNDLENLEIDSAVDTFVDLRLIMTTPEDKKAEAMKTLKEETV
PFFLSKLNALAEENNGHLACKKLTWADLYFAALTGIVKFGAIEGEDIWEKYPALRKVVDN
VEAIDAIKTWINERPVTDF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g16422.t3 CDD cd03039 GST_N_Sigma_like 3 72 0.000
11 g16422.t3 CDD cd03192 GST_C_Sigma_like 83 181 0.000
8 g16422.t3 Gene3D G3DSA:3.40.30.10 Glutaredoxin 3 192 0.000
7 g16422.t3 Gene3D G3DSA:1.20.1050.10 - 75 183 0.000
3 g16422.t3 PANTHER PTHR11571:SF234 GLUTATHIONE S-TRANSFERASE S1 2 199 0.000
4 g16422.t3 PANTHER PTHR11571 GLUTATHIONE S-TRANSFERASE 2 199 0.000
1 g16422.t3 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 71 0.000
2 g16422.t3 Pfam PF14497 Glutathione S-transferase, C-terminal domain 103 194 0.000
10 g16422.t3 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 78 30.290
9 g16422.t3 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 80 199 14.528
13 g16422.t3 SFLD SFLDG01205 AMPS.1 2 198 0.000
14 g16422.t3 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 2 198 0.000
5 g16422.t3 SUPERFAMILY SSF52833 Thioredoxin-like 1 75 0.000
6 g16422.t3 SUPERFAMILY SSF47616 GST C-terminal domain-like 76 199 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values