General information for g1651.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Synaptojanin-1.
Parent gene
- The parent gene g1651 is located on chr_3: 12301158..12303294 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1651 | g1651.t1 | TSS | g1651.t1 | 12298865 | 12298865 |
| chr_3 | g1651 | g1651.t1 | isoform | g1651.t1 | 12299047 | 12303294 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon1 | 12299047 | 12299188 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS1 | 12299047 | 12299188 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon2 | 12299326 | 12300505 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS2 | 12299326 | 12300505 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon3 | 12300570 | 12300955 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS3 | 12300570 | 12300955 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon4 | 12301024 | 12301158 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS4 | 12301024 | 12301158 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon5 | 12301218 | 12301379 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS5 | 12301218 | 12301379 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon6 | 12301467 | 12301762 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS6 | 12301467 | 12301762 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon7 | 12301825 | 12301896 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS7 | 12301825 | 12301896 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon8 | 12301952 | 12302383 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS8 | 12301952 | 12302383 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon9 | 12302441 | 12302725 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS9 | 12302441 | 12302725 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon10 | 12302781 | 12303002 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS10 | 12302781 | 12303002 |
| chr_3 | g1651 | g1651.t1 | exon | g1651.t1.exon11 | 12303061 | 12303294 |
| chr_3 | g1651 | g1651.t1 | cds | g1651.t1.CDS11 | 12303061 | 12303294 |
| chr_3 | g1651 | g1651.t1 | TTS | g1651.t1 | 12303597 | 12303597 |
Sequences
>g1651.t1 Gene=g1651 Length=3546
ATGAGTTTTGGGAAATCATTCCGAGTTTTAGAGAAAAAGGTTGTTGAAAAAGCTAAACCA
GAACAACCCCATAGTATTATTTTAGAGCACAGATCTCGCTCTGAGACCTTACTTTTTGAA
TCTCATGCTATCGCAAGTCTATCTGCTCAAGAAACCGATGCAGTACGAAAGCAATACATT
AAAATTGTTGATGCTTATGGATGTTTGGGAGTATTACAGCTTCATGCTGGTGAAACAACA
CTTCAATATCTTGTTATGATAACGGGATGCTTTTCTATAGGCAAAATTGCTGACTCAGAA
ATTTTCAGAATTACTCAAACACAATTTGTTTCGCTTCAACATCAACAGCCGAATGAGGAT
AAAATTGTAGAAGTTCGCAAAGTACTGAACTCTGGAACATTCTATTTTTCATGGAACACA
AATCCCAATCAGCAATTTGATATAACTCTATGTGCACAAAGAAGACGTAAAACTAATGAA
ACAGATAACCGTTTCTTTTGGAATCGAATGCTGCATATTCCATTTTTGCGATTTGGCATT
GATTTTGACTTTTGGTTATTAAAAGCCATGTGTGGGTCAATTGAAATTAGAACAGTTTAC
GCTGGAAGTAAGCAAGCAAGGGCAATTATCATTTCTCGCTTATCATGTGAACGAGCCGGA
ACACGTTTCAATGTTCGTGGAGTTAATGATGACGGACATGTTGCAAATTTTGTTGAAACT
GAACAAGCTATTTATCTTGATAGTGAAGTTACATCATATGTTCAAACGAGAGGATCTGTA
CCTTTATTTTGGGAACAACCCGGTGTCCAAGTCGGTTCTCATAAAGTAAAATTATCTCGT
GGATTTGAAGCCACAGTACCGGCATTTGATAAACATTTGACAATGATGAAACAGCGATAT
GGTAGACTTGTCATTTGCAATCTATTGGGTACAAGTCTGATTGGAAATAAAGAAGGCGAA
GCAATGCTGAGTAATGAATTTCAGAAGCAGCATGAAAATTCAGTGCATATCGATGTTCCT
CATATCATTTTCGATTATCATCAAGAATGCAGAGGTGGCAATCAAGCAAATTTATCAAAA
CTTAAAGAACGATTTGATAAATGTTGTCGAAGATTTGGTTTCTTTTATGCATCAGGAGAT
GAGGTTGTTCAAGAACAATACGGTACTATACGAACAAATTGTATTGATTGCCTTGATAGA
ACAAATTGCGTTCAAACCTTTATCGGTCTTGATGTGCTAAATGAGCAAATCAAAATTATC
GGATTATCTGATAAGAAACAAACATTTTCGCGATTCGAAGAGGTTTTCAAACAAATGTGG
ATCGCTAATGGAAACGAGGTCTCAAAGATTTATGCTGGCACTGGTGCGATGGGAGCTGGG
AGTAAATTGATTGATGGAGCTCGTTCTGCTGCACGTACTATTCAGAATAATTTATTAGAT
GCTTCAAAACAAGAAGCAATCGATATTCTTCTTCTTGGATCTACTCTCAGCTCGGAATTA
GCTGATAGAGCGAGAATTTTGTTACCAACAAATATGCTTCATGCACCAACACAAGTTTTA
AGAGAAATGTGTTTGAGATATAATGAATACATTTCAACAACAGAAATTCGTGTTGCTATT
GGCACGTACAACGTAAATGGTGGAAAACATTTTCGTAGTGTTGTATACAAAGATTTATCT
TTAATTGATTGGCTTGCGCCCAAAAGCGAATCGATCGTGGAGATCGAGCACTCGAATTCA
GTTCACGATAAAATGGCTGATATTTATGCGATTGGTTTCCAAGAAATTGTCGATTTAAAT
GCTCAAAATATTATGGCAGCCAGCAGTGATAACGCTAAAGCTTGGGCTGAAGAATTGCAA
CGTGTGCTTTCTGTTAAAGAAGATGAACCTTATGCTTTATTAACAAGTCAGCAACTCGTC
GGTGTTTGCTTATATGTATTTATTCGTCCTCAATTAGCAAATTGCTTGCGTGATGTTGCA
ACTGATTCTGTCAAAACTGGATTAGGCGGTGCAACAGGAAACAAAGGAGCTGCAGCTATA
AGATTTGTACTAAACGGTACATCATTTTGTTTTGTTGCTGCTCATTTTGCTGCTGGTCAG
TCACAAGTTGTGGAAAGAAATGCTGATTATGCTGAAATCACTAGAAAAATTACCTTTCCT
ATGGGTAGAACTTTAAAAGGCCACGATTATGTATTTTGGTGTGGTGATTTCAATTATCGT
ATTGATATGAACAAAGATGAAATTAAAGAGTGTGTCAAAAATGGAGATTTGCAAGCAGTA
CTTGAAAATGATCAATTAAAAAAACAACAAGAAGCTGGACAAGTTTTTAATGATTTCCTT
GAAGGAGAAATAACATTTCCACCTACTTATAAGTATGATTTATTCTCGGATGATTATGAT
ACTTCTGAAAAAGCTCGTGCACCAGCTTGGACTGATCGAGTATTATGGCGAAGAAGACAA
CAACAAGCAGATGCTGATAATCCAAATTGGAATCCTGGTCATTTACTTTTCTATGGACGT
GCTGAATTGAAACAGTCTGATCATCGACCAGTTGTTGCAATTTTAGACATTGAAATTTCC
ACTATAGATGCTGATAGACGAGCAAATGTGTTTAATGATGTTATCAAATGCCTCGGACCA
CCAGATGCTACAGTTGTAATTCAATCTGTTCAACATTACACAACAGAGGATGATGAAAGT
ATATATGATGAGAATCTCACTGTTGGATTAGTTCAAGAACTTGCTGAAATTGGTGAAGTG
ACTTTAGTAAGATTTGTTGGTGAAACAATGTGGGTTACTTTTAAGGATGGACAAGCAGCA
CTCGCAGCAGTAAATAGAAAACAAAATTTAAACATTTGCGGTGTCGATCTACATCTTCGT
TTAAAAACGGAAGACTGGCCAAATGAGGTTGAGAAAGAAATTAAAATATGCACAACAAAT
TGCGCTCCACTTTGTGACTATATCGATATTCCATCTGAAGAATATGCAAGCACACCATCA
GAAATTGTAGCAAAAGTAAAACCTCCTCCGCCACGACCTGCATTGCCTAAATCACCACAA
GTTACACCTAAGCATCAACCAAAACATCAAGCTGGTATCATTGACGTTTCACAAATAATT
CGCCCACAACAGCAACAACAACAACCTCCTGAAAGACCATCATTGCCACCTAGACCAGCT
ATTCCTCAAAGACCAGAAATGAAAACAGAACAAAAAACATCTCCTCCATCGCAAGAAACA
CCAAAGCAAAGTCCACTTGAAACGACTTATCAGGCGCCATCAGCAATTTATGAAGAAATC
AATGATGATATTCAAACTCAAGCACAACCTAAAGAGCCACCGCCTCAATTACCTATGAGA
CCATTAGAAATGCCTCCTATTCCTCAAAGAAATAATGTGAATCAATCAAACCAGCAGATT
CCTCAAAAAAATATGAATCAGCCGAATCAATTGCCACAGATTCCTCAAAGAAATAATACG
AATCAATTACCACAAGTTCCAGCAAGACAACCACCACCACCTTTACCAGCAAGAAATATG
AATTAG
>g1651.t1 Gene=g1651 Length=1181
MSFGKSFRVLEKKVVEKAKPEQPHSIILEHRSRSETLLFESHAIASLSAQETDAVRKQYI
KIVDAYGCLGVLQLHAGETTLQYLVMITGCFSIGKIADSEIFRITQTQFVSLQHQQPNED
KIVEVRKVLNSGTFYFSWNTNPNQQFDITLCAQRRRKTNETDNRFFWNRMLHIPFLRFGI
DFDFWLLKAMCGSIEIRTVYAGSKQARAIIISRLSCERAGTRFNVRGVNDDGHVANFVET
EQAIYLDSEVTSYVQTRGSVPLFWEQPGVQVGSHKVKLSRGFEATVPAFDKHLTMMKQRY
GRLVICNLLGTSLIGNKEGEAMLSNEFQKQHENSVHIDVPHIIFDYHQECRGGNQANLSK
LKERFDKCCRRFGFFYASGDEVVQEQYGTIRTNCIDCLDRTNCVQTFIGLDVLNEQIKII
GLSDKKQTFSRFEEVFKQMWIANGNEVSKIYAGTGAMGAGSKLIDGARSAARTIQNNLLD
ASKQEAIDILLLGSTLSSELADRARILLPTNMLHAPTQVLREMCLRYNEYISTTEIRVAI
GTYNVNGGKHFRSVVYKDLSLIDWLAPKSESIVEIEHSNSVHDKMADIYAIGFQEIVDLN
AQNIMAASSDNAKAWAEELQRVLSVKEDEPYALLTSQQLVGVCLYVFIRPQLANCLRDVA
TDSVKTGLGGATGNKGAAAIRFVLNGTSFCFVAAHFAAGQSQVVERNADYAEITRKITFP
MGRTLKGHDYVFWCGDFNYRIDMNKDEIKECVKNGDLQAVLENDQLKKQQEAGQVFNDFL
EGEITFPPTYKYDLFSDDYDTSEKARAPAWTDRVLWRRRQQQADADNPNWNPGHLLFYGR
AELKQSDHRPVVAILDIEISTIDADRRANVFNDVIKCLGPPDATVVIQSVQHYTTEDDES
IYDENLTVGLVQELAEIGEVTLVRFVGETMWVTFKDGQAALAAVNRKQNLNICGVDLHLR
LKTEDWPNEVEKEIKICTTNCAPLCDYIDIPSEEYASTPSEIVAKVKPPPPRPALPKSPQ
VTPKHQPKHQAGIIDVSQIIRPQQQQQQPPERPSLPPRPAIPQRPEMKTEQKTSPPSQET
PKQSPLETTYQAPSAIYEEINDDIQTQAQPKEPPPQLPMRPLEMPPIPQRNNVNQSNQQI
PQKNMNQPNQLPQIPQRNNTNQLPQVPARQPPPPLPARNMN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g1651.t1 | Gene3D | G3DSA:3.60.10.10 | - | 515 | 878 | 1.0E-119 |
| 17 | g1651.t1 | Gene3D | G3DSA:3.30.70.330 | - | 879 | 969 | 8.7E-21 |
| 15 | g1651.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1007 | 1181 | - |
| 12 | g1651.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1049 | 1063 | - |
| 11 | g1651.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1067 | 1110 | - |
| 13 | g1651.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1111 | 1125 | - |
| 10 | g1651.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1128 | 1165 | - |
| 14 | g1651.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1166 | 1181 | - |
| 4 | g1651.t1 | PANTHER | PTHR11200 | INOSITOL 5-PHOSPHATASE | 1 | 976 | 0.0 |
| 5 | g1651.t1 | PANTHER | PTHR11200:SF158 | SYNAPTOJANIN-1 | 1 | 976 | 0.0 |
| 3 | g1651.t1 | Pfam | PF02383 | SacI homology domain | 66 | 351 | 2.6E-65 |
| 2 | g1651.t1 | Pfam | PF03372 | Endonuclease/Exonuclease/phosphatase family | 541 | 848 | 3.0E-13 |
| 1 | g1651.t1 | Pfam | PF08952 | Domain of unknown function (DUF1866) | 856 | 985 | 7.7E-46 |
| 18 | g1651.t1 | ProSiteProfiles | PS50275 | Sac phosphatase domain profile. | 125 | 453 | 72.017 |
| 8 | g1651.t1 | SMART | SM00128 | i5p_5 | 534 | 863 | 2.8E-120 |
| 9 | g1651.t1 | SMART | SM01165 | DUF1866_2 | 856 | 995 | 2.1E-56 |
| 7 | g1651.t1 | SUPERFAMILY | SSF56219 | DNase I-like | 516 | 878 | 6.33E-78 |
| 6 | g1651.t1 | SUPERFAMILY | SSF54928 | RNA-binding domain, RBD | 869 | 962 | 1.09E-7 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0048488 | synaptic vesicle endocytosis | BP |
| GO:0042578 | phosphoric ester hydrolase activity | MF |
| GO:0034595 | phosphatidylinositol phosphate 5-phosphatase activity | MF |
| GO:0046856 | phosphatidylinositol dephosphorylation | BP |
| GO:0003676 | nucleic acid binding | MF |
KEGG
Orthology
- This transcript has been annotated with K20279 (synaptojanin)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
