General information for g16545.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldehyde dehydrogenase family 3 member B1.
Parent gene
- The parent gene g16545 is located on chr_4: 9883580..9889051 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16545 | g16545.t5 | isoform | g16545.t5 | 9878915 | 9886762 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon1 | 9878915 | 9879071 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon2 | 9879135 | 9879265 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon3 | 9879322 | 9879945 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS1 | 9879701 | 9879945 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon4 | 9880006 | 9880159 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS2 | 9880006 | 9880159 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon5 | 9880376 | 9880521 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS3 | 9880376 | 9880521 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon6 | 9880692 | 9880767 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS4 | 9880692 | 9880767 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon7 | 9881320 | 9881419 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS5 | 9881320 | 9881419 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon8 | 9881479 | 9881703 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS6 | 9881479 | 9881703 |
| chr_4 | g16545 | g16545.t5 | exon | g16545.t5.exon9 | 9886715 | 9886762 |
| chr_4 | g16545 | g16545.t5 | cds | g16545.t5.CDS7 | 9886715 | 9886740 |
| chr_4 | g16545 | g16545.t5 | TSS | g16545.t5 | 9886878 | 9886878 |
| chr_4 | g16545 | g16545.t5 | TTS | g16545.t5 | NA | NA |
Sequences
>g16545.t5 Gene=g16545 Length=1661
ATGGAAGACTGGAATTCTTGGGATGATAATGGTGATGCGCCATTGCTGCGATATCAAGCG
GGAATTTCCCTTTGATTTGCTTTCAAATCAAACGAAGAATTTGATAGATTTTGAGATGGA
TGGCTACGAGAACATTTTAGGTCAATTGCGTGCAACATTTCGAAGTGGAAAGACAAAAGA
TTTAAAATACAGAAAGAAACAATTGGAAGCTTTGTTGAGATTGTATGAAGAAAATCGTGA
AGAAATTATCAATGCTTTGGCAGCTGATTTGAGACGGCCAAGACAAGAAGCAATTGTATT
TGAAATTGATGTAATGACAAATGAACTGCTTGGACTGATAAATAATCTTGATGAATATGC
AGCACCGATTAAACCTGATAAAGGAGTCGCAAACATGTTTGACAAAGTGACAATTTTAAA
AGAGCCTTTTGGTGTTGTTTTAGTTATTGGTGCCTGGAATTATCCATTACAACTTTTACT
TGTGCCTGTCGCTGGAGCAATCGCAGCTGGAAATTGTGTCGTTCTCAAACCAAGTGAAAT
TTCAGTTCATTGCTCGAGATTCATTGCTGAAACCTTTCCAAAGTATTTAGATAGTGATGC
CTATCAAGTAATAAGTGGAGGAATTGAAGAAACAACATCACTTTTAAAACATCAATTTGA
TTATATTTTTTACACTGGATCAAATCGTGTTGGTCAAATTGTTCATGCAGCAGCTAATAA
ATATTTAACACCAACTACACTCGAATTAGGCGGAAAATCTCCATGTTACATTGATGACAC
AGTTGATCTCAATAGAGCTGCAAAAAGAATTCTTTGGGGAAAAAATAGCAATGTTGGACA
GACTTGTATTGCACCTGATTACATCATTTGTACCAAAGAAATTGAAAAAAAATTTATCGA
AGAGTCAAGAAATGTGATTAAAGAATGGTATGGTGATGATGTACAACAAAGTCCTGATTA
TGGTAGAATTGCAACTGATGGAAATTTCAAGTGAGTTCAAAAAAATTTTCTTTAAAGATT
TTAAATTTTCTTAATTTTATATAAAAAAAATTTCCAGACGTCTCGTGACATTTATGAATT
GTGGAACAATAGCTTTAGGAGGAAAATTTGATGCATCTGATCGATTTATAGAACCAACAA
TTCTTACAGATGTTAGTCATGATGATCCAGTGATGAGAGAAGAAATTTTTGGACCAATTT
TGCCAATTGTCAATATTCATGACATTCATGATGCAATTGATTTTATTAATGCTCGTGATA
AGCCATTATCACTTTATATTTTTACAAGTAACAACAAAGATAGAGATTTAATCATTGATA
GCACTTCAGCTGGTGCAGTTTGTGTTAATGATACTGTTGTGCATTTTGTTTGTAATTTAC
CATTTGGTGGTGTTGGAGCAAGTGGCATGGGAGCTTATCATGGAAAATATAATTTTGATA
CTTTTACACATGAAAAAGGATGTTTAGAGAAATCAATGGATTATGTGTCTGAAAAATTAT
CTGATGCACGTTATCCACCATATACTGATAATAAAGCATCATATCTTTCATTTATGATGA
AAAAAAGAAAATTTTGGAAAATTCCATTTTTCTCTCATATTCTTGCCTTTGCTTTTGGAG
CAGCTGCAGCATATTATTTGAAGAAGTATTACTTTAACTAA
>g16545.t5 Gene=g16545 Length=323
MIMVMRHCCDIKREFPFDLLSNQTKNLIDFEMDGYENILGQLRATFRSGKTKDLKYRKKQ
LEALLRLYEENREEIINALAADLRRPRQEAIVFEIDVMTNELLGLINNLDEYAAPIKPDK
GVANMFDKVTILKEPFGVVLVIGAWNYPLQLLLVPVAGAIAAGNCVVLKPSEISVHCSRF
IAETFPKYLDSDAYQVISGGIEETTSLLKHQFDYIFYTGSNRVGQIVHAAANKYLTPTTL
ELGGKSPCYIDDTVDLNRAAKRILWGKNSNVGQTCIAPDYIICTKEIEKKFIEESRNVIK
EWYGDDVQQSPDYGRIATDGNFK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g16545.t5 | Coils | Coil | Coil | 51 | 78 | - |
| 6 | g16545.t5 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 28 | 243 | 2.4E-53 |
| 7 | g16545.t5 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 244 | 323 | 7.3E-21 |
| 2 | g16545.t5 | PANTHER | PTHR43570:SF29 | ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q | 30 | 322 | 3.4E-138 |
| 3 | g16545.t5 | PANTHER | PTHR43570 | ALDEHYDE DEHYDROGENASE | 30 | 322 | 3.4E-138 |
| 1 | g16545.t5 | Pfam | PF00171 | Aldehyde dehydrogenase family | 43 | 319 | 1.8E-51 |
| 5 | g16545.t5 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 240 | 247 | - |
| 4 | g16545.t5 | SUPERFAMILY | SSF53720 | ALDH-like | 39 | 322 | 1.96E-74 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed