General information for g16545.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldehyde dehydrogenase, dimeric NADP-preferring.
Parent gene
- The parent gene g16545 is located on chr_4: 9883580..9889051 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16545 | g16545.t7 | isoform | g16545.t7 | 9879707 | 9889051 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon1 | 9879707 | 9879945 |
| chr_4 | g16545 | g16545.t7 | cds | g16545.t7.CDS1 | 9879707 | 9879945 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon2 | 9880006 | 9880159 |
| chr_4 | g16545 | g16545.t7 | cds | g16545.t7.CDS2 | 9880006 | 9880159 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon3 | 9880376 | 9880521 |
| chr_4 | g16545 | g16545.t7 | cds | g16545.t7.CDS3 | 9880376 | 9880521 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon4 | 9880692 | 9880767 |
| chr_4 | g16545 | g16545.t7 | cds | g16545.t7.CDS4 | 9880692 | 9880767 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon5 | 9881320 | 9881419 |
| chr_4 | g16545 | g16545.t7 | cds | g16545.t7.CDS5 | 9881320 | 9881419 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon6 | 9881479 | 9881708 |
| chr_4 | g16545 | g16545.t7 | cds | g16545.t7.CDS6 | 9881479 | 9881636 |
| chr_4 | g16545 | g16545.t7 | exon | g16545.t7.exon7 | 9888946 | 9889051 |
| chr_4 | g16545 | g16545.t7 | TSS | g16545.t7 | 9889157 | 9889157 |
| chr_4 | g16545 | g16545.t7 | TTS | g16545.t7 | NA | NA |
Sequences
>g16545.t7 Gene=g16545 Length=1051
ATAAAATAATAATTTAAAAGTGAGAATATTAAAGGTCAATTTAGCTTGATTTCGATTCAT
TTATGAGCTTAGTGAGGTTTAATCCTCAAATATTTGTTTATATTTGACCAGCGATATCAA
GCGGGAATTTCCCTTTGATTTGCTTTCAAATCAAACGAAGAATTTGATAGATTTTGAGAT
GGATGGCTACGAGAACATTTTAGGTCAATTGCGTGCAACATTTCGAAGTGGAAAGACAAA
AGATTTAAAATACAGAAAGAAACAATTGGAAGCTTTGTTGAGATTGTATGAAGAAAATCG
TGAAGAAATTATCAATGCTTTGGCAGCTGATTTGAGACGGCCAAGACAAGAAGCAATTGT
ATTTGAAATTGATGTAATGACAAATGAACTGCTTGGACTGATAAATAATCTTGATGAATA
TGCAGCACCGATTAAACCTGATAAAGGAGTCGCAAACATGTTTGACAAAGTGACAATTTT
AAAAGAGCCTTTTGGTGTTGTTTTAGTTATTGGTGCCTGGAATTATCCATTACAACTTTT
ACTTGTGCCTGTCGCTGGAGCAATCGCAGCTGGAAATTGTGTCGTTCTCAAACCAAGTGA
AATTTCAGTTCATTGCTCGAGATTCATTGCTGAAACCTTTCCAAAGTATTTAGATAGTGA
TGCCTATCAAGTAATAAGTGGAGGAATTGAAGAAACAACATCACTTTTAAAACATCAATT
TGATTATATTTTTTACACTGGATCAAATCGTGTTGGTCAAATTGTTCATGCAGCAGCTAA
TAAATATTTAACACCAACTACACTCGAATTAGGCGGAAAATCTCCATGTTACATTGATGA
CACAGTTGATCTCAATAGAGCTGCAAAAAGAATTCTTTGGGGAAAAAATAGCAATGTTGG
ACAGACTTGTATTGCACCTGATTACATCATTTGTACCAAAGAAATTGAAAAAAAATTTAT
CGAAGAGTCAAGAAATGTGATTAAAGAATGGTATGGTGATGATGTACAACAAAGTCCTGA
TTATGGTAGAATTGCAACTGATGGAAATTTC
>g16545.t7 Gene=g16545 Length=291
MDGYENILGQLRATFRSGKTKDLKYRKKQLEALLRLYEENREEIINALAADLRRPRQEAI
VFEIDVMTNELLGLINNLDEYAAPIKPDKGVANMFDKVTILKEPFGVVLVIGAWNYPLQL
LLVPVAGAIAAGNCVVLKPSEISVHCSRFIAETFPKYLDSDAYQVISGGIEETTSLLKHQ
FDYIFYTGSNRVGQIVHAAANKYLTPTTLELGGKSPCYIDDTVDLNRAAKRILWGKNSNV
GQTCIAPDYIICTKEIEKKFIEESRNVIKEWYGDDVQQSPDYGRIATDGNF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g16545.t7 | Coils | Coil | Coil | 20 | 47 | - |
| 6 | g16545.t7 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 2 | 212 | 2.1E-53 |
| 7 | g16545.t7 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 213 | 291 | 1.0E-20 |
| 2 | g16545.t7 | PANTHER | PTHR43570:SF29 | ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q | 5 | 291 | 1.4E-137 |
| 3 | g16545.t7 | PANTHER | PTHR43570 | ALDEHYDE DEHYDROGENASE | 5 | 291 | 1.4E-137 |
| 1 | g16545.t7 | Pfam | PF00171 | Aldehyde dehydrogenase family | 12 | 286 | 1.9E-51 |
| 5 | g16545.t7 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 209 | 216 | - |
| 4 | g16545.t7 | SUPERFAMILY | SSF53720 | ALDH-like | 8 | 289 | 1.96E-74 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
