General information for g16591.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Trypsin-1.
Parent gene
- The parent gene g16591 is located on chr_4: 10138309..10139720 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16591 | g16591.t10 | isoform | g16591.t10 | 10137971 | 10139720 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon1 | 10137971 | 10138218 |
| chr_4 | g16591 | g16591.t10 | TTS | g16591.t10 | 10137978 | 10137978 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon2 | 10138337 | 10138389 |
| chr_4 | g16591 | g16591.t10 | cds | g16591.t10.CDS1 | 10138364 | 10138389 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon3 | 10138770 | 10138948 |
| chr_4 | g16591 | g16591.t10 | cds | g16591.t10.CDS2 | 10138770 | 10138948 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon4 | 10139068 | 10139195 |
| chr_4 | g16591 | g16591.t10 | cds | g16591.t10.CDS3 | 10139068 | 10139195 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon5 | 10139248 | 10139369 |
| chr_4 | g16591 | g16591.t10 | cds | g16591.t10.CDS4 | 10139248 | 10139369 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon6 | 10139434 | 10139589 |
| chr_4 | g16591 | g16591.t10 | cds | g16591.t10.CDS5 | 10139434 | 10139491 |
| chr_4 | g16591 | g16591.t10 | exon | g16591.t10.exon7 | 10139668 | 10139720 |
| chr_4 | g16591 | g16591.t10 | TSS | g16591.t10 | 10139750 | 10139750 |
Sequences
>g16591.t10 Gene=g16591 Length=939
ATGTTGATTTTCAATTTCTTAATTCTTCTTTTTTTCTTCAATTTTGAAAGTAGTTTTAAA
CGCAAATGTTTTACGAAAGGGAAAAATTGTAGGCGGTTACTCAGCTGATTATTATCAATT
TCCTTATCAAGCGTCATTGCGTACTGCTTTAATGAGTACGCACTTTTGCGGGGCTTTTTT
ATTAACTGAACGTTGGCTCATGAGTGCAGGTCACTGCACTGATAAAAGAAAACCATCCGG
TGTTGTCGTCGTTGTTGGTGCATTTACTAGAGCAAAAGATGAAGGTGTCAAACATAATGT
GCTACTTTTAGTCACACATCCTGAATTTGATGCAAAATCACTTCAAAATGACATTTCAAT
GATCAAAACTGAAACTTTTATTGATTTTACAATCAGCATTCGACCAGTTCGATTGCAAGC
AATGCCAGCTGAAGAAGGAATAGAAGCTTTTGTATCTGGTTGGGGTTACATAAATTCAAA
AGGAACAAATCCTGATGTTTTACAATGGATAAAAGTAAAAACAATTAATATTGATGAATG
TCGTGAAAAAATGAGTAAACAAAATGCTGAAAGAATTTTTGAAACAAATATTTGTGCTGA
TGCCATGGAAAGTACTGGATCTAATGGAAATGGTGGAGCTTTTTCATATTTAGGTGACAG
TTGATGGAGCTTTAATAGGAATTGTTTCATGGGGAGTGCCATGCGGTAAAGGTTTACCTG
ATGTTTACACTCAAGTTTCACCATTCAAAGATTGGATTGATGAAACAATTGATTTTCCTG
AAATTGAAGAAGATGATGGCGATTATGAATATAATTTGATTGACATAATTCAAGATGATG
CACATGATATGGAATTTATGGCAACTTAAATTTTGTGAACTTGATTTGATAAATAAAATT
TTTTGATTATTTTCAATTGTTTCGAAAGAATTTAATTCA
>g16591.t10 Gene=g16591 Length=170
MSTHFCGAFLLTERWLMSAGHCTDKRKPSGVVVVVGAFTRAKDEGVKHNVLLLVTHPEFD
AKSLQNDISMIKTETFIDFTISIRPVRLQAMPAEEGIEAFVSGWGYINSKGTNPDVLQWI
KVKTINIDECREKMSKQNAERIFETNICADAMESTGSNGNGGAFSYLGDS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g16591.t10 | CDD | cd00190 | Tryp_SPc | 2 | 170 | 2.05161E-41 |
| 6 | g16591.t10 | Gene3D | G3DSA:2.40.10.10 | - | 3 | 85 | 1.6E-33 |
| 7 | g16591.t10 | Gene3D | G3DSA:2.40.10.10 | - | 86 | 154 | 1.6E-33 |
| 2 | g16591.t10 | PANTHER | PTHR24276 | POLYSERASE-RELATED | 2 | 164 | 3.0E-26 |
| 3 | g16591.t10 | PANTHER | PTHR24276:SF89 | IP07603P | 2 | 164 | 3.0E-26 |
| 1 | g16591.t10 | Pfam | PF00089 | Trypsin | 3 | 156 | 3.4E-28 |
| 9 | g16591.t10 | ProSitePatterns | PS00134 | Serine proteases, trypsin family, histidine active site. | 17 | 22 | - |
| 11 | g16591.t10 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 1 | 170 | 16.533 |
| 10 | g16591.t10 | SMART | SM00020 | trypsin_2 | 2 | 168 | 2.6E-7 |
| 4 | g16591.t10 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 3 | 154 | 2.18E-33 |
| 5 | g16591.t10 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed