General information for g16737.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Organic cation transporter protein.
Parent gene
- The parent gene g16737 is located on chr_4: 10752438..10754785 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16737 | g16737.t1 | isoform | g16737.t1 | 10752438 | 10754785 |
| chr_4 | g16737 | g16737.t1 | exon | g16737.t1.exon1 | 10752438 | 10752580 |
| chr_4 | g16737 | g16737.t1 | cds | g16737.t1.CDS1 | 10752438 | 10752580 |
| chr_4 | g16737 | g16737.t1 | exon | g16737.t1.exon2 | 10752636 | 10752894 |
| chr_4 | g16737 | g16737.t1 | cds | g16737.t1.CDS2 | 10752636 | 10752894 |
| chr_4 | g16737 | g16737.t1 | exon | g16737.t1.exon3 | 10752965 | 10753674 |
| chr_4 | g16737 | g16737.t1 | cds | g16737.t1.CDS3 | 10752965 | 10753674 |
| chr_4 | g16737 | g16737.t1 | exon | g16737.t1.exon4 | 10753734 | 10754032 |
| chr_4 | g16737 | g16737.t1 | cds | g16737.t1.CDS4 | 10753734 | 10754032 |
| chr_4 | g16737 | g16737.t1 | exon | g16737.t1.exon5 | 10754553 | 10754785 |
| chr_4 | g16737 | g16737.t1 | cds | g16737.t1.CDS5 | 10754553 | 10754785 |
| chr_4 | g16737 | g16737.t1 | TTS | g16737.t1 | 10754846 | 10754846 |
| chr_4 | g16737 | g16737.t1 | TSS | g16737.t1 | NA | NA |
Sequences
>g16737.t1 Gene=g16737 Length=1644
ATGGACTTTGATTTAATACTCGATGAAATTGGAGAATTTGGAAAATTCCAATTGTTGAAT
TACTTGCTAATTTGCTTGCCTGTGTTTTACGCTGCTGCCAATTCATTATCATACGTTTTT
ACAGCAAGAAATCCAAATTATAGATGTTTCATTGATCAATGTGACGACTATCAAAAAACA
AAATATGAAACTGATTGGGTTAAAGACGTAGTTCCAGGAACAATATCACAAGTTTCTGGA
CATTTCACACCTGAAAATTGTTTGAAATATGAATTTTCATTACAAACAAATTTAACTTTT
CCGTTAGTAAATGGAACATGTGATGCACATTGGTTTAGTCATGATACAGTAAGATGTAAT
CAATGGATGTTTGAAGAAGGTGAAACAACAATTGTTAATGAGTGGCCAAATGAACTAACA
TGTTCAGAAAATCAATGGAAACTTGCTCTTATTGGTTCAATTCATTTTGCTGGAATAATG
ATAGGATCTGGAATTTTCGGATTTCTAGCAGATTGTTATGGTCGTAAGAAAATCTTCATT
ATCGCTATAATTTTCATGTCAATCACTGGTGTCGGTCAAGCAGTTTCAACATCTTATTTA
ATGTTTGCAATTTTTGCTCTTCTCAATGCCATCGGTACATCAGGCGTATATCCGTTAGCA
TTCGTCCTCGGAGTCGAAATGGTTGGCAAAAATAAGAGAGAAATGTCGGGTGTAGTGTTG
AATTATTTTTACTCTGTTGGTGAGGCACTTGTTGGAATTATAGCATGGCTCGATGGAAAT
TGGCGAAGTCTTCAATATTGGGTGTCAGTGCCACCAATTGCTTTTATTGTTTATCATTGG
GTTATTCCTGAATCAGCACGTTGGCTGATTGCAAAAAAACGAAATCGCAAAGCACTCAAA
ATTATAAGCAGGGCAGCAAAAAATAATGGCGTTGAATTATCACAAAGTATTCTCGATAGC
TTCAATAATGACGTAGGTGATGATGGTGTAAAAACTGCTGACAATGATGAAGGTGAAGCT
AACACTGGTCATCATGTAAGATTGAGTGATTATATTGCAGTTGCCAAATCAAAAGTTATT
GCTGTGAGATGTTTAATTTTATTTTTTATTTGGGGAACAAATGCTTTTGTTTTTTATGGT
CTTTCATTGAATTCAGTAAATCTAAGCGGAAACATTTACTTAAATTTCATCCTTGGTTGT
CTCATTGAAATCCCTGGAAATTCAATAGCATGGATAATAATGAATAAAATCGGCAGAAGA
TTATCATTGACATCTTCACTTCTTCTTTGTGGTGTGACATGCATTGCTGGTGGTTTTGTG
CCTGAAAAAATCTTTTGGGTACAAATTTTGCTATTTTTAGTTGGCAAAATGGCAATCACC
TCGTCCTTTGCAATTGTTTTTGTTTATTCAGCTGAAATGATTCCAACGATTGTAAGGAGC
GGAGGAGTAGGAGCATTTTCAACATTTTCACGTTTAGGCGCACTTTTGGCACCATTTGTT
CCATTACTTAAATTTGTTTTTAATTTCCTGCCATTGTTGATTTTCGGTGTTTTTGCTTTT
CTGTCAGGTTTACTTGCATTTTTACTTCCTGAAACACTTGGGAAAAAATTACCAGATACA
ATTAGTGAAGCTGAAATGATTTAA
>g16737.t1 Gene=g16737 Length=547
MDFDLILDEIGEFGKFQLLNYLLICLPVFYAAANSLSYVFTARNPNYRCFIDQCDDYQKT
KYETDWVKDVVPGTISQVSGHFTPENCLKYEFSLQTNLTFPLVNGTCDAHWFSHDTVRCN
QWMFEEGETTIVNEWPNELTCSENQWKLALIGSIHFAGIMIGSGIFGFLADCYGRKKIFI
IAIIFMSITGVGQAVSTSYLMFAIFALLNAIGTSGVYPLAFVLGVEMVGKNKREMSGVVL
NYFYSVGEALVGIIAWLDGNWRSLQYWVSVPPIAFIVYHWVIPESARWLIAKKRNRKALK
IISRAAKNNGVELSQSILDSFNNDVGDDGVKTADNDEGEANTGHHVRLSDYIAVAKSKVI
AVRCLILFFIWGTNAFVFYGLSLNSVNLSGNIYLNFILGCLIEIPGNSIAWIIMNKIGRR
LSLTSSLLLCGVTCIAGGFVPEKIFWVQILLFLVGKMAITSSFAIVFVYSAEMIPTIVRS
GGVGAFSTFSRLGALLAPFVPLLKFVFNFLPLLIFGVFAFLSGLLAFLLPETLGKKLPDT
ISEAEMI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 31 | g16737.t1 | CDD | cd17317 | MFS_SLC22 | 119 | 530 | 3.40167E-92 |
| 5 | g16737.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 124 | 541 | 6.3E-71 |
| 2 | g16737.t1 | PANTHER | PTHR24064 | SOLUTE CARRIER FAMILY 22 MEMBER | 3 | 546 | 3.7E-134 |
| 3 | g16737.t1 | PANTHER | PTHR24064:SF335 | FI24011P1-RELATED | 3 | 546 | 3.7E-134 |
| 1 | g16737.t1 | Pfam | PF00083 | Sugar (and other) transporter | 141 | 537 | 3.7E-30 |
| 9 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 20 | - |
| 26 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 40 | - |
| 18 | g16737.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 41 | 147 | - |
| 22 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 148 | 169 | - |
| 10 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 170 | 177 | - |
| 20 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 178 | 196 | - |
| 17 | g16737.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 197 | 201 | - |
| 24 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 202 | 225 | - |
| 8 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 226 | 236 | - |
| 27 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 237 | 257 | - |
| 14 | g16737.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 258 | 268 | - |
| 29 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 269 | 290 | - |
| 7 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 291 | 359 | - |
| 25 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 360 | 381 | - |
| 15 | g16737.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 382 | 392 | - |
| 30 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 393 | 414 | - |
| 11 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 415 | 420 | - |
| 21 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 421 | 439 | - |
| 13 | g16737.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 440 | 444 | - |
| 28 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 445 | 469 | - |
| 6 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 470 | 480 | - |
| 19 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 481 | 503 | - |
| 16 | g16737.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 504 | 508 | - |
| 23 | g16737.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 509 | 529 | - |
| 12 | g16737.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 530 | 547 | - |
| 44 | g16737.t1 | ProSiteProfiles | PS50850 | Major facilitator superfamily (MFS) profile. | 99 | 534 | 21.097 |
| 4 | g16737.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 145 | 539 | 2.62E-49 |
| 38 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 20 | 42 | - |
| 40 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 148 | 170 | - |
| 41 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 177 | 199 | - |
| 43 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 203 | 225 | - |
| 42 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 238 | 257 | - |
| 32 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 267 | 289 | - |
| 37 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 360 | 382 | - |
| 36 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 392 | 414 | - |
| 39 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 421 | 440 | - |
| 35 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 445 | 467 | - |
| 33 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 480 | 502 | - |
| 34 | g16737.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 507 | 529 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K08202 (MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
