General information for g16823.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Dephospho-CoA kinase domain-containing protein.
Parent gene
- The parent gene g16823 is located on chr_4: 11255613..11256567 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16823 | g16823.t1 | TSS | g16823.t1 | 11254667 | 11254667 |
| chr_4 | g16823 | g16823.t1 | isoform | g16823.t1 | 11254749 | 11256199 |
| chr_4 | g16823 | g16823.t1 | exon | g16823.t1.exon1 | 11254749 | 11254863 |
| chr_4 | g16823 | g16823.t1 | cds | g16823.t1.CDS1 | 11254749 | 11254863 |
| chr_4 | g16823 | g16823.t1 | exon | g16823.t1.exon2 | 11255613 | 11256199 |
| chr_4 | g16823 | g16823.t1 | cds | g16823.t1.CDS2 | 11255613 | 11256199 |
| chr_4 | g16823 | g16823.t1 | TTS | g16823.t1 | 11256403 | 11256403 |
Sequences
>g16823.t1 Gene=g16823 Length=702
ATGTTTTTAGTCGCTGTAACTGGTGGCATATCTTGTGGCAAAACAAAAGTTTGTGAAGTA
TTTCAAAAATATTACAATGTTGCTGTTGTTAATGCAGATGCCATATCTAGAGAAATTGTG
GAACCAGGAAAGCCAGTCTGGAAACAAATTAAAGAAAATTTCGGTGATGAAGTTTTTAAC
GAAGATGAAACTTTAAATCGTGAAAAATTAGGTCAAATAATTTTTGATAATGTTGAAAAG
CGAAGAATTCTCAATCGAATAACACATCCAGTAATTCATCGTGAAATTTATAAGCAAGTT
TTTAAATATTTTATTCAAGGCAAACCATTTGTAGTTCTTGAATTGCCATTGCTTTTTGAA
GTGAATTCAAATCTCATAAATTTCATTTATAAAATTATTTGTGTTGTTGCTGAAGAAGAC
ATTCAAATTGCAAGACTTATGGATCGAAATAATTTGTCATTGACTGAAGCAAAGAAAAGA
ATCAAAGCACAAATGTCATTGGAAGAGAAAGCAAAAATGTCACATTATGTTATTGAAAAT
TCTGGATCACAAAGAGACATGGAAGAGCAAGCATTGAGTATTATTAAAATTATTGTCGAC
AGCAATCATCATTGGAAACTAAGGAGCATGCTTTTAGGAGCTTTTATGTCAATCGTTGCT
GGAGTCACGTGGCTGATTAATAAAAAATATAAATTTTTCTAG
>g16823.t1 Gene=g16823 Length=233
MFLVAVTGGISCGKTKVCEVFQKYYNVAVVNADAISREIVEPGKPVWKQIKENFGDEVFN
EDETLNREKLGQIIFDNVEKRRILNRITHPVIHREIYKQVFKYFIQGKPFVVLELPLLFE
VNSNLINFIYKIICVVAEEDIQIARLMDRNNLSLTEAKKRIKAQMSLEEKAKMSHYVIEN
SGSQRDMEEQALSIIKIIVDSNHHWKLRSMLLGAFMSIVAGVTWLINKKYKFF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g16823.t1 | CDD | cd02022 | DPCK | 3 | 183 | 2.84291E-68 |
| 6 | g16823.t1 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 205 | 2.3E-69 |
| 4 | g16823.t1 | Hamap | MF_00376 | Dephospho-CoA kinase [coaE]. | 1 | 201 | 25.535963 |
| 2 | g16823.t1 | PANTHER | PTHR10695:SF46 | BIFUNCTIONAL COENZYME A SYNTHASE-RELATED | 1 | 188 | 5.1E-43 |
| 3 | g16823.t1 | PANTHER | PTHR10695 | DEPHOSPHO-COA KINASE-RELATED | 1 | 188 | 5.1E-43 |
| 1 | g16823.t1 | Pfam | PF01121 | Dephospho-CoA kinase | 3 | 185 | 9.6E-55 |
| 8 | g16823.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 204 | - |
| 9 | g16823.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 205 | 226 | - |
| 7 | g16823.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 227 | 233 | - |
| 13 | g16823.t1 | ProSiteProfiles | PS51219 | Dephospho-CoA kinase (DPCK) domain profile. | 3 | 209 | 50.035 |
| 5 | g16823.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 1 | 197 | 3.53E-35 |
| 12 | g16823.t1 | TIGRFAM | TIGR00152 | TIGR00152: dephospho-CoA kinase | 3 | 190 | 1.2E-52 |
| 11 | g16823.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 210 | 227 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004140 | dephospho-CoA kinase activity | MF |
| GO:0015937 | coenzyme A biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K00859 (dephospho-CoA kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
