Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Dephospho-CoA kinase domain-containing protein.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g16823 g16823.t3 TSS g16823.t3 11254667 11254667
chr_4 g16823 g16823.t3 isoform g16823.t3 11254749 11256199
chr_4 g16823 g16823.t3 exon g16823.t3.exon1 11254749 11254867
chr_4 g16823 g16823.t3 cds g16823.t3.CDS1 11254825 11254867
chr_4 g16823 g16823.t3 exon g16823.t3.exon2 11255625 11256199
chr_4 g16823 g16823.t3 cds g16823.t3.CDS2 11255625 11256199
chr_4 g16823 g16823.t3 TTS g16823.t3 11256403 11256403

Sequences

>g16823.t3 Gene=g16823 Length=694
ATGTTTTTAGTCGCTGTAACTGGTGGCATATCTTGTGGCAAAACAAAAGTTTGTGAAGTA
TTTCAAAAATATTACAATGTTGCTGTTGTTAATGCAGATGCCATATCTAGAGAAAGTAAG
AAAGCCAGTCTGGAAACAAATTAAAGAAAATTTCGGTGATGAAGTTTTTAACGAAGATGA
AACTTTAAATCGTGAAAAATTAGGTCAAATAATTTTTGATAATGTTGAAAAGCGAAGAAT
TCTCAATCGAATAACACATCCAGTAATTCATCGTGAAATTTATAAGCAAGTTTTTAAATA
TTTTATTCAAGGCAAACCATTTGTAGTTCTTGAATTGCCATTGCTTTTTGAAGTGAATTC
AAATCTCATAAATTTCATTTATAAAATTATTTGTGTTGTTGCTGAAGAAGACATTCAAAT
TGCAAGACTTATGGATCGAAATAATTTGTCATTGACTGAAGCAAAGAAAAGAATCAAAGC
ACAAATGTCATTGGAAGAGAAAGCAAAAATGTCACATTATGTTATTGAAAATTCTGGATC
ACAAAGAGACATGGAAGAGCAAGCATTGAGTATTATTAAAATTATTGTCGACAGCAATCA
TCATTGGAAACTAAGGAGCATGCTTTTAGGAGCTTTTATGTCAATCGTTGCTGGAGTCAC
GTGGCTGATTAATAAAAAATATAAATTTTTCTAG

>g16823.t3 Gene=g16823 Length=205
MLLLLMQMPYLEKVRKPVWKQIKENFGDEVFNEDETLNREKLGQIIFDNVEKRRILNRIT
HPVIHREIYKQVFKYFIQGKPFVVLELPLLFEVNSNLINFIYKIICVVAEEDIQIARLMD
RNNLSLTEAKKRIKAQMSLEEKAKMSHYVIENSGSQRDMEEQALSIIKIIVDSNHHWKLR
SMLLGAFMSIVAGVTWLINKKYKFF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g16823.t3 CDD cd02022 DPCK 13 155 6.22757E-49
6 g16823.t3 Gene3D G3DSA:3.40.50.300 - 10 177 1.6E-49
4 g16823.t3 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 173 13.808576
2 g16823.t3 PANTHER PTHR10695:SF46 BIFUNCTIONAL COENZYME A SYNTHASE-RELATED 14 160 7.1E-27
3 g16823.t3 PANTHER PTHR10695 DEPHOSPHO-COA KINASE-RELATED 14 160 7.1E-27
1 g16823.t3 Pfam PF01121 Dephospho-CoA kinase 15 157 3.2E-37
7 g16823.t3 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 1 181 -
9 g16823.t3 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 182 199 -
8 g16823.t3 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 200 205 -
13 g16823.t3 ProSiteProfiles PS51219 Dephospho-CoA kinase (DPCK) domain profile. 1 181 34.074
5 g16823.t3 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 14 169 3.82E-21
12 g16823.t3 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 16 162 1.7E-34
11 g16823.t3 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 182 199 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0004140 dephospho-CoA kinase activity MF
GO:0015937 coenzyme A biosynthetic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed