General information for g16843.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Bis(5’-nucleosyl)-tetraphosphatase [asymmetrical].
Parent gene
- The parent gene g16843 is located on chr_4: 11366750..11367875 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16843 | g16843.t1 | TTS | g16843.t1 | 11366720 | 11366720 |
| chr_4 | g16843 | g16843.t1 | isoform | g16843.t1 | 11366750 | 11367355 |
| chr_4 | g16843 | g16843.t1 | exon | g16843.t1.exon1 | 11366750 | 11367064 |
| chr_4 | g16843 | g16843.t1 | cds | g16843.t1.CDS1 | 11366750 | 11367064 |
| chr_4 | g16843 | g16843.t1 | exon | g16843.t1.exon2 | 11367239 | 11367355 |
| chr_4 | g16843 | g16843.t1 | cds | g16843.t1.CDS2 | 11367239 | 11367355 |
| chr_4 | g16843 | g16843.t1 | TSS | g16843.t1 | 11367443 | 11367443 |
Sequences
>g16843.t1 Gene=g16843 Length=432
ATGACAGCAAAAAGAGCAACAGGATTTTTAATTTATCGTTTGATATCAAATGAAATTCAA
TATTTATTAATGAAAGCTAGTTATGGAAATTTTCATTGGACACCACCAAAGGGTCATGTT
GATCCAGGTGAATCAGATTATGAAACAGCACTTCGTGAAACTCATGAAGAAGCAGGCTAT
AATGAAGATGATTTGATAATTTACAAAGATTTAAATAAAACTCTAAATTATCAAGTTAAA
GGAAAACCAAAAGTTGTGATCTACTGGCTTGCTCAATTAAAAAATCCTCAGCATATGCCG
ACACTTTCTGATGAACATACAGAATTTAAATTCTTGAATAAAAACGATGCAATTAAAATT
TCTGGTTACAAAGATTTTGCTGAAATGGTTGAATATTTTGATAAAGAAATAAGAAAAATT
CATGGAATTTAA
>g16843.t1 Gene=g16843 Length=143
MTAKRATGFLIYRLISNEIQYLLMKASYGNFHWTPPKGHVDPGESDYETALRETHEEAGY
NEDDLIIYKDLNKTLNYQVKGKPKVVIYWLAQLKNPQHMPTLSDEHTEFKFLNKNDAIKI
SGYKDFAEMVEYFDKEIRKIHGI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g16843.t1 | CDD | cd03428 | Ap4A_hydrolase_human_like | 3 | 135 | 6.04648E-55 |
| 9 | g16843.t1 | Gene3D | G3DSA:3.90.79.10 | Nucleoside Triphosphate Pyrophosphohydrolase | 2 | 139 | 2.1E-33 |
| 2 | g16843.t1 | PANTHER | PTHR21340:SF0 | BIS(5’-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] | 4 | 137 | 9.7E-34 |
| 3 | g16843.t1 | PANTHER | PTHR21340 | DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT | 4 | 137 | 9.7E-34 |
| 4 | g16843.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 19 | 37 | 5.5E-14 |
| 6 | g16843.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 64 | 85 | 5.5E-14 |
| 7 | g16843.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 85 | 103 | 5.5E-14 |
| 5 | g16843.t1 | PRINTS | PR01405 | Bis(5’-nucleosyl)-tetraphosphatase signature | 105 | 123 | 5.5E-14 |
| 1 | g16843.t1 | Pfam | PF00293 | NUDIX domain | 6 | 131 | 4.6E-17 |
| 11 | g16843.t1 | ProSitePatterns | PS00893 | Nudix box signature. | 38 | 59 | - |
| 12 | g16843.t1 | ProSiteProfiles | PS51462 | Nudix hydrolase domain profile. | 2 | 137 | 14.024 |
| 8 | g16843.t1 | SUPERFAMILY | SSF55811 | Nudix | 5 | 137 | 1.34E-23 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0008796 | bis(5’-nucleosyl)-tetraphosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01518 (bis(5’-nucleosidyl)-tetraphosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
