General information for g16924.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein kinase fused.
Parent gene
- The parent gene g16924 is located on chr_4: 11735342..11737545 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16924 | g16924.t1 | TTS | g16924.t1 | 11734824 | 11734824 |
| chr_4 | g16924 | g16924.t1 | isoform | g16924.t1 | 11735342 | 11737545 |
| chr_4 | g16924 | g16924.t1 | exon | g16924.t1.exon1 | 11735342 | 11736864 |
| chr_4 | g16924 | g16924.t1 | cds | g16924.t1.CDS1 | 11735342 | 11736864 |
| chr_4 | g16924 | g16924.t1 | exon | g16924.t1.exon2 | 11736918 | 11737350 |
| chr_4 | g16924 | g16924.t1 | cds | g16924.t1.CDS2 | 11736918 | 11737350 |
| chr_4 | g16924 | g16924.t1 | exon | g16924.t1.exon3 | 11737411 | 11737545 |
| chr_4 | g16924 | g16924.t1 | cds | g16924.t1.CDS3 | 11737411 | 11737545 |
| chr_4 | g16924 | g16924.t1 | TSS | g16924.t1 | 11737612 | 11737612 |
Sequences
>g16924.t1 Gene=g16924 Length=2091
ATGGAAAAATTTGAATCATTTTCAATTCAAAATTATAAAATTTTACATCTTATTGGAACA
GGATCATTTGGGAAAGTTTTTAAAGCATTTGACAATGAAACACAAAATGTTGTTGCATTG
AAAGTTTTATCAAAAAATGGAAGATCAACAAAAGAACTTTCAGCATTAAAACAAGAAGCA
AATATTCAACAAAATCTTCGTCATCCAAACATAATTCAACTTTTTTCCTCTTTTGAAACT
GATAAAGAATTAGTTTTTGTATGTGAATATGCAGTTTCAGATCTTCATAAACTTTTAGCA
AAAGTTGGATCACTTGGTGAACAACGAACACAAAAATTGTCATATGATCTTATTAGTGCT
CTTTATTATCTTCATTCACATCGAATTTTACATCGTGATTTAAAACCACCAAATATTTTA
TTGGATAAAAATTATAAAGCAAAAGTGTGTGATTTTGGTTTGGCACGAAATATGACAATA
GGGACACAAATTTTAACATCAATCAAAGGAACACCACTTTATATGGCACCTGAATTACTT
GATGGTCGTGGTTATGGACATGAAGCTGATCTTTGGTCACTTGGTTGTATAATTTATGAA
ATGTTAGCCGGTGAATCTCCTTTTAATACAAGATCGATTTTGCATTTAATGCAATTAATT
CGTTATGGAAATATCAAATGGCCAAGTTTTCTTTCATCAACTTGTATTTCTTTCCTCAAA
GGACTTCTTGACAACAATCCAACAAAAAGAATGAGTTGGGATGAAATTCTTGATCATAAA
TTTGTCAAAGGAAACATTTTGATTCTCACAACTGATAAATCAATTTCTGATTCGCCATTT
ACAAGACCTAAAAATGCAGCAAAAACTGATCCATTACCATCAGTCAATCAACAACGTAGA
ATTGAAGTTCAACAAATTGAAGACATTGCATCATCTCGTGATTCCATTAAAGTTAATTTA
AATCTACAAAGTGACATGGATGAAACTGACAATGAAACTGAATTAAATATTTTAAAACAA
GAACCAATTGCAATTGGTCAAATTCCATTTCAGCATGATTTTAATCAATTTCAAATGGAT
TTGCAGCCTAAAATTCAACCATTGGCTGAAAATGCTAATATGGTCATGCATAGATTTATG
GATAATGTTGATCCAGAATTACAACAATTTTTAATGATGCCATTAGTGACAACAGCAACA
AATTCAATGAAAACAGTTCAAAAAAGTGAAATTCGAAGATCAATAAAAATTCAATCAGAT
CATGTTTCAACTGATGTTTCAAGTATTCCAGTGGAAACTGAAGAATGGCTGCAATTCATT
TTTAAATCAATGCAAGAAATTTTAGATGGTGATTTAGACATTTATAAACAGGAAAATATG
ATGACAATGATTGTTGGATTGTTAAGAGATTCAAAATATAGTCCACAATTAATAGAACAT
GCTGTACAAATTATAAGTTTGCCATATGCAATTGATATGCCACAATCAATGATTGAAGAA
ATTGATCGAATGTATTTGCAATTGAAACTTGTGCCAAATCTTGTTTATGCTTCAAAATTA
TTGTGCAGTAAAAATTCAACTGGTGAATTTAATGAACAAGAAATGAAAACTTTGGCAGGA
ATTTATGATGTTGTAGTTTTTTTGGTTTATGCAAGTGAAACTTTTTTGCAATTGCTTTGT
GATGCAATGGCACTTCTTAATCTTGATCATTTATTTAGGAATTTTATTATCAATGGTCTA
GAGAAAGAAACAAAAGAAGCTGTGAGACTTACAGGATCAATTTTAGCTCTCATTTGTGCA
ATTTTACAAGAATTGCCAGAAAATGCAAAATTGATTGAAAAAATTATTTTTCATGATGAT
GTTGACTTGTGTAAACTTTTAAGACATAAAAATGATAAAATTAGACTAAGAGTTTGCATA
ATGTTGAGATTATTGGGAAGATTTTGTTGCTATGCATTGCAAAGTTATTGGAATGTTGAA
ATTTCAAATGTTATTCAAAAAGAATTGATAAATGATGAAAATAATGATGTTAAAAATGCT
GCAAATAATATTTTGGAAGAATTTAAATGTTTTGGTTGGTTTAAAAAATAA
>g16924.t1 Gene=g16924 Length=696
MEKFESFSIQNYKILHLIGTGSFGKVFKAFDNETQNVVALKVLSKNGRSTKELSALKQEA
NIQQNLRHPNIIQLFSSFETDKELVFVCEYAVSDLHKLLAKVGSLGEQRTQKLSYDLISA
LYYLHSHRILHRDLKPPNILLDKNYKAKVCDFGLARNMTIGTQILTSIKGTPLYMAPELL
DGRGYGHEADLWSLGCIIYEMLAGESPFNTRSILHLMQLIRYGNIKWPSFLSSTCISFLK
GLLDNNPTKRMSWDEILDHKFVKGNILILTTDKSISDSPFTRPKNAAKTDPLPSVNQQRR
IEVQQIEDIASSRDSIKVNLNLQSDMDETDNETELNILKQEPIAIGQIPFQHDFNQFQMD
LQPKIQPLAENANMVMHRFMDNVDPELQQFLMMPLVTTATNSMKTVQKSEIRRSIKIQSD
HVSTDVSSIPVETEEWLQFIFKSMQEILDGDLDIYKQENMMTMIVGLLRDSKYSPQLIEH
AVQIISLPYAIDMPQSMIEEIDRMYLQLKLVPNLVYASKLLCSKNSTGEFNEQEMKTLAG
IYDVVVFLVYASETFLQLLCDAMALLNLDHLFRNFIINGLEKETKEAVRLTGSILALICA
ILQELPENAKLIEKIIFHDDVDLCKLLRHKNDKIRLRVCIMLRLLGRFCCYALQSYWNVE
ISNVIQKELINDENNDVKNAANNILEEFKCFGWFKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g16924.t1 | Coils | Coil | Coil | 667 | 687 | - |
| 5 | g16924.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 4 | 341 | 1.1E-90 |
| 4 | g16924.t1 | Gene3D | G3DSA:1.25.10.10 | - | 551 | 692 | 1.6E-5 |
| 2 | g16924.t1 | PANTHER | PTHR22983 | PROTEIN KINASE RELATED | 10 | 345 | 2.5E-121 |
| 1 | g16924.t1 | Pfam | PF00069 | Protein kinase domain | 12 | 262 | 5.1E-73 |
| 8 | g16924.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 18 | 41 | - |
| 7 | g16924.t1 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 129 | 141 | - |
| 10 | g16924.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 12 | 262 | 51.099 |
| 9 | g16924.t1 | SMART | SM00220 | serkin_6 | 12 | 262 | 2.0E-94 |
| 3 | g16924.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 7 | 276 | 8.5E-88 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K06228 (fused)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
