General information for g17112.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as GPI ethanolamine phosphate transferase 1.
Parent gene
- The parent gene g17112 is located on chr_4: 12515527..12516557 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17112 | g17112.t4 | isoform | g17112.t4 | 12514486 | 12515527 |
| chr_4 | g17112 | g17112.t4 | exon | g17112.t4.exon1 | 12514486 | 12515011 |
| chr_4 | g17112 | g17112.t4 | cds | g17112.t4.CDS1 | 12514487 | 12515011 |
| chr_4 | g17112 | g17112.t4 | exon | g17112.t4.exon2 | 12515144 | 12515527 |
| chr_4 | g17112 | g17112.t4 | cds | g17112.t4.CDS2 | 12515144 | 12515527 |
| chr_4 | g17112 | g17112.t4 | TSS | g17112.t4 | NA | NA |
| chr_4 | g17112 | g17112.t4 | TTS | g17112.t4 | NA | NA |
Sequences
>g17112.t4 Gene=g17112 Length=910
ATGAAATTTCTAGTCACTTTTGCAATTTTTCTTCACTTTCTATTTCTACTCAGTATTTTC
TACATTTACTTCCGCACAATAATCGTTCAAGACTTAAAACCATTAAAATCACTTGATAAT
CCACCAGCAAAAAGACTCGTCCTAATTGTCTCTGATGGACTTCGTGCTGAATCATTTTTT
GATCAAAATTACAATCGAACTCCATTTTTGAAAAATATTTTACTCACAAGAGGCTTAATT
GGTGTGTCACATACTCATGTTCCTACTGAATCAAGACCTGGTCATGTTGCATTGATTGCT
GGCGTTTATGAAGATCCATCATCAATTTTTAAAGGCTGGCAGGAAAATTTTGTTGAATTT
GATTCAGTTTTTAATAGAAGTCAAATAACTTACGCATGGGGAAGTCCAGACATTGTTCCA
ATGTTTTCAAAAGGTGCAACACCCAATCGAGTTATCACAGAAACTTACGACTCAAATTCA
GAAATTTTTGGAGCAAATGCACCAACATTTTTACTTGACAAATGGGTTTTTGATCGCGTA
AAAATTTTCCTAAATACAAAAGCTGAAAATTTAAAAGAAAAATCTGGAGTGATATTTTTT
CTTCATCTTCTTGGCATGGACACAAGTGGGCACGTTCATAAGCCACATTCAGAAAAATTT
ACTGAAAATTTGAAATTTGTTGATCGTGGAATTGGTGAAATTGTGGAAATGATTGACAAA
ATTTTTGATGACAATTTGACAGCTTTTATTTTTACATCAGACCATGGAATGACAAATAGA
GGTTCACATGGTGCTGGTCATCAACATGAGACTGAAACTCCATTTTTAGCATGGGGTGCT
GGCATAAATTATTGGAAAATTGCAAAAGATGATTTTTTAACAAGAACTCATATAACAATT
GATGGACAAA
>g17112.t4 Gene=g17112 Length=303
MKFLVTFAIFLHFLFLLSIFYIYFRTIIVQDLKPLKSLDNPPAKRLVLIVSDGLRAESFF
DQNYNRTPFLKNILLTRGLIGVSHTHVPTESRPGHVALIAGVYEDPSSIFKGWQENFVEF
DSVFNRSQITYAWGSPDIVPMFSKGATPNRVITETYDSNSEIFGANAPTFLLDKWVFDRV
KIFLNTKAENLKEKSGVIFFLHLLGMDTSGHVHKPHSEKFTENLKFVDRGIGEIVEMIDK
IFDDNLTAFIFTSDHGMTNRGSHGAGHQHETETPFLAWGAGINYWKIAKDDFLTRTHITI
DGQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g17112.t4 | CDD | cd16020 | GPI_EPT_1 | 41 | 291 | 4.85602E-139 |
| 6 | g17112.t4 | Gene3D | G3DSA:3.40.720.10 | Alkaline Phosphatase | 29 | 298 | 1.6E-40 |
| 3 | g17112.t4 | PANTHER | PTHR12250 | PHOSPHATIDYLINOSITOL GLYCAN, CLASS N | 2 | 289 | 1.1E-132 |
| 2 | g17112.t4 | Pfam | PF01663 | Type I phosphodiesterase / nucleotide pyrophosphatase | 46 | 103 | 1.1E-5 |
| 1 | g17112.t4 | Pfam | PF01663 | Type I phosphodiesterase / nucleotide pyrophosphatase | 189 | 259 | 2.4E-10 |
| 8 | g17112.t4 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 9 | g17112.t4 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 24 | - |
| 7 | g17112.t4 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 25 | 303 | - |
| 5 | g17112.t4 | SUPERFAMILY | SSF53649 | Alkaline phosphatase-like | 40 | 283 | 4.94E-32 |
| 4 | g17112.t4 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006506 | GPI anchor biosynthetic process | BP |
| GO:0051377 | mannose-ethanolamine phosphotransferase activity | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0005789 | endoplasmic reticulum membrane | CC |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
