General information for g17114.t40
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Lysosomal aspartic protease.
Parent gene
- The parent gene g17114 is located on chr_4: 12519041..12520450 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17114 | g17114.t40 | TTS | g17114.t40 | 12518088 | 12518088 |
| chr_4 | g17114 | g17114.t40 | isoform | g17114.t40 | 12518645 | 12519222 |
| chr_4 | g17114 | g17114.t40 | exon | g17114.t40.exon1 | 12518645 | 12518963 |
| chr_4 | g17114 | g17114.t40 | cds | g17114.t40.CDS1 | 12518646 | 12518963 |
| chr_4 | g17114 | g17114.t40 | exon | g17114.t40.exon2 | 12519024 | 12519222 |
| chr_4 | g17114 | g17114.t40 | cds | g17114.t40.CDS2 | 12519024 | 12519104 |
| chr_4 | g17114 | g17114.t40 | TSS | g17114.t40 | NA | NA |
Sequences
>g17114.t40 Gene=g17114 Length=518
ATTTGCAGAAGCAGTTTCAGAACCCGGTTTAGTTTTTGTTGCTGCTAAATTTGATGGAAT
TCTTGGATTAGGCTACAAATCAATTTCAGTTGATGGAGTTGAACCAGTTTTCTATAACAT
GTACAATCAAGGACTCATTTCAGAGCCAATTTTCTCATTTTATTTGAATCGTGATCCAAA
TGGCAAAGAAGGTGGAGAAATTATTTTTGGTGGAAGTGATCCAGATCATTATGAAGGTGA
TTTCACTTATCTCCCAGTCAATCGCAAAGCATACTGGCAATTCAAAATGGATGGAGTGAA
AATTGGTGACAAAACTTTCTGTAATGGTGGATGCCAAGCAATTGCTGACACTGGAACATC
ACTCATTGCTGGACCAACTGATGAAGTTACAGCAATTAACAAAGCCATCGGTGGAACACC
AATTTTAAATGGACAATACATGGTTAATTGTGACATGATACCAAATTTGCCTACAATTAA
ATTCACTTTGGGTGGCAAGGAATTTGCACTTGATGGAT
>g17114.t40 Gene=g17114 Length=133
MYNQGLISEPIFSFYLNRDPNGKEGGEIIFGGSDPDHYEGDFTYLPVNRKAYWQFKMDGV
KIGDKTFCNGGCQAIADTGTSLIAGPTDEVTAINKAIGGTPILNGQYMVNCDMIPNLPTI
KFTLGGKEFALDG
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g17114.t40 | Gene3D | G3DSA:2.40.70.10 | Acid Proteases | 1 | 133 | 3.6E-47 |
| 2 | g17114.t40 | PANTHER | PTHR47966:SF21 | NAPSIN-A | 2 | 131 | 1.9E-51 |
| 3 | g17114.t40 | PANTHER | PTHR47966 | BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED | 2 | 131 | 1.9E-51 |
| 4 | g17114.t40 | PRINTS | PR00792 | Pepsin (A1) aspartic protease family signature | 26 | 39 | 4.0E-8 |
| 5 | g17114.t40 | PRINTS | PR00792 | Pepsin (A1) aspartic protease family signature | 74 | 85 | 4.0E-8 |
| 1 | g17114.t40 | Pfam | PF00026 | Eukaryotic aspartyl protease | 1 | 131 | 7.2E-46 |
| 7 | g17114.t40 | ProSitePatterns | PS00141 | Eukaryotic and viral aspartyl proteases active site. | 74 | 85 | - |
| 9 | g17114.t40 | ProSiteProfiles | PS51767 | Peptidase family A1 domain profile. | 1 | 133 | 31.809 |
| 6 | g17114.t40 | SUPERFAMILY | SSF50630 | Acid proteases | 1 | 132 | 7.8E-44 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006508 | proteolysis | BP |
| GO:0004190 | aspartic-type endopeptidase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed