General information for g17291.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Open rectifier potassium channel protein 1.
Parent gene
- The parent gene g17291 is located on chr_4: 13044456..13046473 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17291 | g17291.t1 | TSS | g17291.t1 | 13040427 | 13040427 |
| chr_4 | g17291 | g17291.t1 | isoform | g17291.t1 | 13040611 | 13044456 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon1 | 13040611 | 13040752 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS1 | 13040611 | 13040752 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon2 | 13041363 | 13041422 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS2 | 13041363 | 13041422 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon3 | 13041489 | 13041605 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS3 | 13041489 | 13041605 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon4 | 13041664 | 13041729 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS4 | 13041664 | 13041729 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon5 | 13041795 | 13041850 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS5 | 13041795 | 13041850 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon6 | 13041911 | 13042071 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS6 | 13041911 | 13042071 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon7 | 13042221 | 13042273 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS7 | 13042221 | 13042273 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon8 | 13042339 | 13042440 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS8 | 13042339 | 13042440 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon9 | 13042499 | 13042538 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS9 | 13042499 | 13042538 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon10 | 13042602 | 13042749 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS10 | 13042602 | 13042749 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon11 | 13042842 | 13043303 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS11 | 13042842 | 13043303 |
| chr_4 | g17291 | g17291.t1 | exon | g17291.t1.exon12 | 13043656 | 13044456 |
| chr_4 | g17291 | g17291.t1 | cds | g17291.t1.CDS12 | 13043656 | 13044456 |
| chr_4 | g17291 | g17291.t1 | TTS | g17291.t1 | 13044503 | 13044503 |
Sequences
>g17291.t1 Gene=g17291 Length=2208
ATGAGTCCAAAGCAATTTATTGCACTTTTATTATTTTATATTTTTTATTTATTATTTGGT
GCAAGTGTTTTTTATTACACTGAACATGGATATGAAACTGGAAAAAGAGCTGATGAAAAT
GCTGCTCGTCTTGAAGTTAATGCTTTGTTATTAAATAATCTACCAAACAATACCGAACTT
AAAGAAGAAATATTAGGCAAAGTGACAGATTATTGTGGAAAATCTGTGAGGCATCCTTCA
ACAGATTCATTTGTTCCGCCTTATATTTGGTCTTTTTATCACTCATTTTATTTCTCATTT
ATTATTTGTAGTACTGTTGGTTATGGAAATATTTCACCAAGTCATTCATTTGGTCGAATT
TTTTTAATATTTTATGCAATTGTCGGATTGCCATTGCATGCAATACTTTTTGGAGTTATG
GGTAATTTTTGGGGAAAAACTTTTGTCAGAATGTATAAAAAGTACAAAGATTACAAAAAA
TCTACGGATATAAATTACAGACCCAGAAAATTAACTCTTATTGGAAAAATTGCTCTTTAT
GTCACACCTGCCATTATTTTGTTAATTTTCATACCTGCCATTTTATTCACATACTTTGAA
AGATGGGACTATGTTACATCAGTTTATTATGCTTTTGTTACTTTAACAACAATTGGTTTT
GGTGACTATGCTGCAACGTTTAGAGATTTTCAAGAGAGCACTTTTGGATATTATTTTGTA
GCTTATCAAATTTTTGTTATTTTTTGGTTTATTGCAGGAGTAAGCTATGTTGCAATGTGT
ATTGGATTTCTCATTCAAGGCTTGAAAAGTAAACAAGTCAAAAATATTGAACACAATTTG
GCTTTAAATCTCAAAGACACTCAAAAGAGACTTTGGCAAGGTATGCAACGAGATGTTGGA
TTTCTACGAAAAATTCTTAATGAAGTTAATTTTTCTAAGTACAAGCCAATTTACAAAGAT
CCTGAAGAGATCAAACAAAAATTTCGCTCAACTCGTTCACAATCATGTCCACGTTTATTC
ATTTACGATGATGAAGACGAATTTGATTATGATGAAGAAGAAATTTTAAAGTACAAAAGA
AAACGTGCAAATTCTGAAACTCATAAATTTAAACATCGAAATTCAATGTTTGTTCATACA
CATTCTGATACAGAATTAAATAAAATTGATCGACAAAAAACTTTTGAAGCGCTCAAAGCT
GAAATTGAACCGGCGGAAATTCTTGCAAAAGTTACGATTGCATTGGGAGAAATTTTGGAA
GATGAAAATAATCAAGAAGACAACAATGCAGAAGTTCAAGAAAATGAAGAAAATTTCGTG
ACTTTGATGCCAGGAGAAAACCTTTATGCTGGACGTGATCGAAGAGCTTTATCAGTTGTT
CAAATTCCTATAGAAGATTTAGTGATGACACCAAACGAATGGACATGGTCAGGTGCAAAT
ACACAAATAAACGAACTAAGAGAAAAATTATCAAAACCTAAGAAAAATCTTTACCAAAAG
TTCTTCACAAAGAAAATTGAAAATAATTTGGACAAAACAAAAAGTTCACCACAAATTTCA
AATGGTTCAATTTCATCAATTCCACAAAGTTTGAATATTTTCAATCGTAAAAATTCAAAT
ATGTTAAAGAGACATTCTTTAGCACCTTGGAATGAATTAAATTCACAAAATTACAATGAA
CGAAGAGATTCAATAAAAAGTTTACATAAAATATCATCACATATAAAAAGTAGGGGAAGT
ATATTCTCAATGTCAGGCAATGAAAAGCAACAAAATCTTCTCGAAACAACAACTGTAGCT
GATTTAATAAGAGCAATTGAAAAAGTCAACATTATTTCATCATCAAATGAATCACTAACG
AAAAAATTAGGTTATTTATCAAGAAAATCATCACAAGTGACACTAGCAAATGATGATGGA
GTAAACCATTTCAATAAGCCACAAAGAGGAAGAATTCAAAGTTGCGTACTTGAAAATTCT
TTCTTTGATCATCATAAACTTAAAACTTTGGCAGAAACAAGAAAAGAAAGTGCAAAAAAT
TTAAGAAATGATTTATTAAGAACAAAATTTAGACGACATTTAAGTGAAAGTAATGATGAT
CAAAATAATGCAGAAAATATTTTTAAGAAAGATAATTTAACAGCTAGTTTTAGATTAAAT
ATTCCACAACAACAATATTATTATAAAAAAAATGAAAATTCTTCTTGA
>g17291.t1 Gene=g17291 Length=735
MSPKQFIALLLFYIFYLLFGASVFYYTEHGYETGKRADENAARLEVNALLLNNLPNNTEL
KEEILGKVTDYCGKSVRHPSTDSFVPPYIWSFYHSFYFSFIICSTVGYGNISPSHSFGRI
FLIFYAIVGLPLHAILFGVMGNFWGKTFVRMYKKYKDYKKSTDINYRPRKLTLIGKIALY
VTPAIILLIFIPAILFTYFERWDYVTSVYYAFVTLTTIGFGDYAATFRDFQESTFGYYFV
AYQIFVIFWFIAGVSYVAMCIGFLIQGLKSKQVKNIEHNLALNLKDTQKRLWQGMQRDVG
FLRKILNEVNFSKYKPIYKDPEEIKQKFRSTRSQSCPRLFIYDDEDEFDYDEEEILKYKR
KRANSETHKFKHRNSMFVHTHSDTELNKIDRQKTFEALKAEIEPAEILAKVTIALGEILE
DENNQEDNNAEVQENEENFVTLMPGENLYAGRDRRALSVVQIPIEDLVMTPNEWTWSGAN
TQINELREKLSKPKKNLYQKFFTKKIENNLDKTKSSPQISNGSISSIPQSLNIFNRKNSN
MLKRHSLAPWNELNSQNYNERRDSIKSLHKISSHIKSRGSIFSMSGNEKQQNLLETTTVA
DLIRAIEKVNIISSSNESLTKKLGYLSRKSSQVTLANDDGVNHFNKPQRGRIQSCVLENS
FFDHHKLKTLAETRKESAKNLRNDLLRTKFRRHLSESNDDQNNAENIFKKDNLTASFRLN
IPQQQYYYKKNENSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g17291.t1 | Coils | Coil | Coil | 415 | 436 | - |
| 9 | g17291.t1 | Gene3D | G3DSA:1.10.287.70 | - | 3 | 281 | 8.0E-60 |
| 3 | g17291.t1 | PANTHER | PTHR11003:SF304 | OPEN RECTIFIER POTASSIUM CHANNEL PROTEIN 1 | 5 | 305 | 2.2E-58 |
| 4 | g17291.t1 | PANTHER | PTHR11003 | POTASSIUM CHANNEL, SUBFAMILY K | 5 | 305 | 2.2E-58 |
| 6 | g17291.t1 | PRINTS | PR01333 | Two pore domain K+ channel signature | 101 | 129 | 1.8E-13 |
| 5 | g17291.t1 | PRINTS | PR01333 | Two pore domain K+ channel signature | 216 | 225 | 1.8E-13 |
| 2 | g17291.t1 | Pfam | PF07885 | Ion channel | 89 | 143 | 1.3E-15 |
| 1 | g17291.t1 | Pfam | PF07885 | Ion channel | 185 | 266 | 5.4E-12 |
| 15 | g17291.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 22 | g17291.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 26 | - |
| 12 | g17291.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 27 | 86 | - |
| 21 | g17291.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 87 | 108 | - |
| 17 | g17291.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 109 | 119 | - |
| 23 | g17291.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 120 | 144 | - |
| 13 | g17291.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 145 | 176 | - |
| 20 | g17291.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 177 | 198 | - |
| 16 | g17291.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 199 | 203 | - |
| 19 | g17291.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 204 | 225 | - |
| 11 | g17291.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 226 | 236 | - |
| 18 | g17291.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 237 | 265 | - |
| 14 | g17291.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 266 | 735 | - |
| 8 | g17291.t1 | SUPERFAMILY | SSF81324 | Voltage-gated potassium channels | 5 | 163 | 3.79E-28 |
| 7 | g17291.t1 | SUPERFAMILY | SSF81324 | Voltage-gated potassium channels | 178 | 282 | 3.66E-20 |
| 29 | g17291.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 5 | 27 | - |
| 25 | g17291.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 90 | 112 | - |
| 24 | g17291.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 122 | 144 | - |
| 28 | g17291.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 177 | 199 | - |
| 27 | g17291.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 204 | 226 | - |
| 26 | g17291.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 239 | 261 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005267 | potassium channel activity | MF |
| GO:0071805 | potassium ion transmembrane transport | BP |
KEGG
Orthology
- This transcript has been annotated with K04913 (potassium channel subfamily K member 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed