General information for g17291.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Open rectifier potassium channel protein 1.
Parent gene
- The parent gene g17291 is located on chr_4: 13044456..13046473 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17291 | g17291.t3 | TSS | g17291.t3 | 13040427 | 13040427 |
| chr_4 | g17291 | g17291.t3 | isoform | g17291.t3 | 13040611 | 13044071 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon1 | 13040611 | 13040752 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS1 | 13040611 | 13040752 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon2 | 13041489 | 13041605 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS2 | 13041489 | 13041605 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon3 | 13041664 | 13041729 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS3 | 13041664 | 13041729 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon4 | 13041795 | 13041850 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS4 | 13041795 | 13041850 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon5 | 13041911 | 13042071 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS5 | 13041911 | 13042071 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon6 | 13042221 | 13042273 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS6 | 13042221 | 13042273 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon7 | 13042339 | 13042440 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS7 | 13042339 | 13042440 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon8 | 13042499 | 13042538 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS8 | 13042499 | 13042538 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon9 | 13042602 | 13042749 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS9 | 13042602 | 13042749 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon10 | 13042842 | 13043303 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS10 | 13042842 | 13043303 |
| chr_4 | g17291 | g17291.t3 | exon | g17291.t3.exon11 | 13043656 | 13044071 |
| chr_4 | g17291 | g17291.t3 | cds | g17291.t3.CDS11 | 13043656 | 13044069 |
| chr_4 | g17291 | g17291.t3 | TTS | g17291.t3 | 13044503 | 13044503 |
Sequences
>g17291.t3 Gene=g17291 Length=1763
ATGAGTCCAAAGCAATTTATTGCACTTTTATTATTTTATATTTTTTATTTATTATTTGGT
GCAAGTGTTTTTTATTACACTGAACATGGATATGAAACTGGAAAAAGAGCTGATGAAAAT
GCTGCTCGTCTTGAAGTTAATGTGACAGATTATTGTGGAAAATCTGTGAGGCATCCTTCA
ACAGATTCATTTGTTCCGCCTTATATTTGGTCTTTTTATCACTCATTTTATTTCTCATTT
ATTATTTGTAGTACTGTTGGTTATGGAAATATTTCACCAAGTCATTCATTTGGTCGAATT
TTTTTAATATTTTATGCAATTGTCGGATTGCCATTGCATGCAATACTTTTTGGAGTTATG
GGTAATTTTTGGGGAAAAACTTTTGTCAGAATGTATAAAAAGTACAAAGATTACAAAAAA
TCTACGGATATAAATTACAGACCCAGAAAATTAACTCTTATTGGAAAAATTGCTCTTTAT
GTCACACCTGCCATTATTTTGTTAATTTTCATACCTGCCATTTTATTCACATACTTTGAA
AGATGGGACTATGTTACATCAGTTTATTATGCTTTTGTTACTTTAACAACAATTGGTTTT
GGTGACTATGCTGCAACGTTTAGAGATTTTCAAGAGAGCACTTTTGGATATTATTTTGTA
GCTTATCAAATTTTTGTTATTTTTTGGTTTATTGCAGGAGTAAGCTATGTTGCAATGTGT
ATTGGATTTCTCATTCAAGGCTTGAAAAGTAAACAAGTCAAAAATATTGAACACAATTTG
GCTTTAAATCTCAAAGACACTCAAAAGAGACTTTGGCAAGGTATGCAACGAGATGTTGGA
TTTCTACGAAAAATTCTTAATGAAGTTAATTTTTCTAAGTACAAGCCAATTTACAAAGAT
CCTGAAGAGATCAAACAAAAATTTCGCTCAACTCGTTCACAATCATGTCCACGTTTATTC
ATTTACGATGATGAAGACGAATTTGATTATGATGAAGAAGAAATTTTAAAGTACAAAAGA
AAACGTGCAAATTCTGAAACTCATAAATTTAAACATCGAAATTCAATGTTTGTTCATACA
CATTCTGATACAGAATTAAATAAAATTGATCGACAAAAAACTTTTGAAGCGCTCAAAGCT
GAAATTGAACCGGCGGAAATTCTTGCAAAAGTTACGATTGCATTGGGAGAAATTTTGGAA
GATGAAAATAATCAAGAAGACAACAATGCAGAAGTTCAAGAAAATGAAGAAAATTTCGTG
ACTTTGATGCCAGGAGAAAACCTTTATGCTGGACGTGATCGAAGAGCTTTATCAGTTGTT
CAAATTCCTATAGAAGATTTAGTGATGACACCAAACGAATGGACATGGTCAGGTGCAAAT
ACACAAATAAACGAACTAAGAGAAAAATTATCAAAACCTAAGAAAAATCTTTACCAAAAG
TTCTTCACAAAGAAAATTGAAAATAATTTGGACAAAACAAAAAGTTCACCACAAATTTCA
AATGGTTCAATTTCATCAATTCCACAAAGTTTGAATATTTTCAATCGTAAAAATTCAAAT
ATGTTAAAGAGACATTCTTTAGCACCTTGGAATGAATTAAATTCACAAAATTACAATGAA
CGAAGAGATTCAATAAAAAGTTTACATAAAATATCATCACATATAAAAAGTAGGGGAAGT
ATATTCTCAATGTCAGGCAATGAAAAGCAACAAAATCTTCTCGAAACAACAACTGTAGCT
GATTTAATAAGAGCAATTGAAAA
>g17291.t3 Gene=g17291 Length=587
MSPKQFIALLLFYIFYLLFGASVFYYTEHGYETGKRADENAARLEVNVTDYCGKSVRHPS
TDSFVPPYIWSFYHSFYFSFIICSTVGYGNISPSHSFGRIFLIFYAIVGLPLHAILFGVM
GNFWGKTFVRMYKKYKDYKKSTDINYRPRKLTLIGKIALYVTPAIILLIFIPAILFTYFE
RWDYVTSVYYAFVTLTTIGFGDYAATFRDFQESTFGYYFVAYQIFVIFWFIAGVSYVAMC
IGFLIQGLKSKQVKNIEHNLALNLKDTQKRLWQGMQRDVGFLRKILNEVNFSKYKPIYKD
PEEIKQKFRSTRSQSCPRLFIYDDEDEFDYDEEEILKYKRKRANSETHKFKHRNSMFVHT
HSDTELNKIDRQKTFEALKAEIEPAEILAKVTIALGEILEDENNQEDNNAEVQENEENFV
TLMPGENLYAGRDRRALSVVQIPIEDLVMTPNEWTWSGANTQINELREKLSKPKKNLYQK
FFTKKIENNLDKTKSSPQISNGSISSIPQSLNIFNRKNSNMLKRHSLAPWNELNSQNYNE
RRDSIKSLHKISSHIKSRGSIFSMSGNEKQQNLLETTTVADLIRAIE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g17291.t3 | Coils | Coil | Coil | 395 | 416 | - |
| 9 | g17291.t3 | Gene3D | G3DSA:1.10.287.70 | - | 3 | 261 | 5.0E-56 |
| 3 | g17291.t3 | PANTHER | PTHR11003:SF304 | OPEN RECTIFIER POTASSIUM CHANNEL PROTEIN 1 | 5 | 293 | 1.5E-57 |
| 4 | g17291.t3 | PANTHER | PTHR11003 | POTASSIUM CHANNEL, SUBFAMILY K | 5 | 293 | 1.5E-57 |
| 6 | g17291.t3 | PRINTS | PR01333 | Two pore domain K+ channel signature | 81 | 109 | 1.2E-13 |
| 5 | g17291.t3 | PRINTS | PR01333 | Two pore domain K+ channel signature | 196 | 205 | 1.2E-13 |
| 2 | g17291.t3 | Pfam | PF07885 | Ion channel | 67 | 123 | 1.1E-13 |
| 1 | g17291.t3 | Pfam | PF07885 | Ion channel | 165 | 246 | 3.9E-12 |
| 16 | g17291.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 20 | g17291.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 26 | - |
| 13 | g17291.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 27 | 66 | - |
| 21 | g17291.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 67 | 88 | - |
| 14 | g17291.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 89 | 99 | - |
| 23 | g17291.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 100 | 124 | - |
| 12 | g17291.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 125 | 156 | - |
| 19 | g17291.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 157 | 178 | - |
| 15 | g17291.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 179 | 183 | - |
| 18 | g17291.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 184 | 205 | - |
| 11 | g17291.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 206 | 216 | - |
| 22 | g17291.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 217 | 245 | - |
| 17 | g17291.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 246 | 587 | - |
| 7 | g17291.t3 | SUPERFAMILY | SSF81324 | Voltage-gated potassium channels | 5 | 142 | 1.83E-27 |
| 8 | g17291.t3 | SUPERFAMILY | SSF81324 | Voltage-gated potassium channels | 159 | 262 | 2.49E-20 |
| 29 | g17291.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 5 | 27 | - |
| 27 | g17291.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 70 | 92 | - |
| 26 | g17291.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 102 | 124 | - |
| 25 | g17291.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 157 | 179 | - |
| 24 | g17291.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 184 | 206 | - |
| 28 | g17291.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 219 | 241 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005267 | potassium channel activity | MF |
| GO:0071805 | potassium ion transmembrane transport | BP |
KEGG
Orthology
- This transcript has been annotated with K04913 (potassium channel subfamily K member 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed