General information for g17514.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione S-transferase 1, isoform D.
Parent gene
- The parent gene g17514 is located on chr_4: 13765025..13766935 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17514 | g17514.t1 | TSS | g17514.t1 | 13764075 | 13764075 |
| chr_4 | g17514 | g17514.t1 | isoform | g17514.t1 | 13764270 | 13765025 |
| chr_4 | g17514 | g17514.t1 | exon | g17514.t1.exon1 | 13764270 | 13764370 |
| chr_4 | g17514 | g17514.t1 | cds | g17514.t1.CDS1 | 13764270 | 13764370 |
| chr_4 | g17514 | g17514.t1 | exon | g17514.t1.exon2 | 13764428 | 13765025 |
| chr_4 | g17514 | g17514.t1 | cds | g17514.t1.CDS2 | 13764428 | 13765025 |
| chr_4 | g17514 | g17514.t1 | TTS | g17514.t1 | 13765368 | 13765368 |
Sequences
>g17514.t1 Gene=g17514 Length=699
ATGACACTTCATCGTCCAACGCTTTTTTATGTTCCATTAAGTCCACCAGCGCGAGCTGTA
ATGCTTACTGCCAAAGAAATTGAGCTTGATCTTGAAGTCAAACTAGTTGATCTTTTTGCT
CTTGAACAAAAAAGTGCATCATATCGAAAAATCAATCCACTTGGTAAAATTCCAGCCTTA
ATTGATGATGACATTTATATTTGGGATTCTCATGCAATTATGATTTATATTGTTGAAAAA
TTTGCTGAAGATGATTCACTTTATCCACATGATTTAATCTTACGTACGAAAGTCAATCAA
ATGTTATTTTTCGAGGCAACTGTTTTATTTCAATTACTTTCTGACATTGTTGTACCGATT
TATCATCAAAAAATGAAGGAAGTTCCACAATCACTTACTAATTCGGTCAAAGATGCTTAT
GATGTGATTGAAACGATGTTGAAAAGTGGTCAAAAATACATTTGTGGTGAAACTTTGACC
ATTGCTGATTTGAGCATTTGGACTACTTTGCTATCATTGAGATTTCTAGTGCCAATTGAT
AGCAATAAATTTCTTAAACTTGATAACTGGTTAAAATTGATGAAATCGAGGCCAACTTAC
GATATGAATCAAAGTGGAGCTAATCAGCATTATGGATTCATAAGATCATGCATAGAAGGA
AAACCTGTCATTCCAGTGCCAATTACTGTTCAAAAATAA
>g17514.t1 Gene=g17514 Length=232
MTLHRPTLFYVPLSPPARAVMLTAKEIELDLEVKLVDLFALEQKSASYRKINPLGKIPAL
IDDDIYIWDSHAIMIYIVEKFAEDDSLYPHDLILRTKVNQMLFFEATVLFQLLSDIVVPI
YHQKMKEVPQSLTNSVKDAYDVIETMLKSGQKYICGETLTIADLSIWTTLLSLRFLVPID
SNKFLKLDNWLKLMKSRPTYDMNQSGANQHYGFIRSCIEGKPVIPVPITVQK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g17514.t1 | CDD | cd03177 | GST_C_Delta_Epsilon | 95 | 209 | 0.000 |
| 8 | g17514.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 83 | 0.000 |
| 7 | g17514.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 84 | 221 | 0.000 |
| 3 | g17514.t1 | PANTHER | PTHR43969:SF4 | FI01423P-RELATED | 6 | 218 | 0.000 |
| 4 | g17514.t1 | PANTHER | PTHR43969 | GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED | 6 | 218 | 0.000 |
| 1 | g17514.t1 | Pfam | PF02798 | Glutathione S-transferase, N-terminal domain | 7 | 78 | 0.000 |
| 2 | g17514.t1 | Pfam | PF14497 | Glutathione S-transferase, C-terminal domain | 123 | 198 | 0.000 |
| 10 | g17514.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 4 | 85 | 22.408 |
| 9 | g17514.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 91 | 214 | 15.923 |
| 12 | g17514.t1 | SFLD | SFLDG01153 | Main.4: Theta-like | 6 | 216 | 0.000 |
| 13 | g17514.t1 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 6 | 216 | 0.000 |
| 5 | g17514.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 4 | 89 | 0.000 |
| 6 | g17514.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 76 | 200 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00799 (glutathione S-transferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
