General information for g17533.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cyclin-dependent kinase 9.
Parent gene
- The parent gene g17533 is located on chr_4: 13803714..13804665 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17533 | g17533.t1 | TTS | g17533.t1 | 13801720 | 13801720 |
| chr_4 | g17533 | g17533.t1 | isoform | g17533.t1 | 13802136 | 13804542 |
| chr_4 | g17533 | g17533.t1 | exon | g17533.t1.exon1 | 13802136 | 13803429 |
| chr_4 | g17533 | g17533.t1 | cds | g17533.t1.CDS1 | 13802136 | 13803429 |
| chr_4 | g17533 | g17533.t1 | exon | g17533.t1.exon2 | 13804520 | 13804542 |
| chr_4 | g17533 | g17533.t1 | cds | g17533.t1.CDS2 | 13804520 | 13804542 |
| chr_4 | g17533 | g17533.t1 | TSS | g17533.t1 | 13804665 | 13804665 |
Sequences
>g17533.t1 Gene=g17533 Length=1317
ATGGTCATCATTTCTACACAAAAACACCAAACAGCAACAGTGTCCTCGAAAATGTCCGAA
TATCATAATAAGGCTCATTTGAAGAGGCTCCAAAATGGTGTCAATATCAATCGTCATCTT
CAACCTGCTCAGCGTCAAAATAAAATCTCAAATCTCCCTCAATTTCGTCAAGCACTCGCT
CACGAGCATCCAAATTTGCCTCGTGATAACATCAAATTAAGTCCAAACATGCCACCAACC
CCACCGCCATCGCCTGAAATGTCAAAATATGAGAGAATTCTTAAAATCGGCCAAGGAACA
TTTGGTGAAGTTTACAAAGTCAAATCAAAATATGACAATCAAATTTTAGCCATGAAATCA
ATCAAATATAAAGAAAGAGCTGAAGGACTTCCAATTAATCTTGTTCGAGAAATAAAAATT
CTCAAGCAAACTGATAACAAAAATATTATCAAATTGGTCGATGTATTTCAACATTTCAAC
AATATTCATTTAGTCCTCGAATTTTGCCATCATGATCTCGCTGGAATTCTTTCAAATCAA
AGAATTAGCTTCAAACCATCTGAAATTAAATCATTGATGAAACAATTGATGAATGCACTT
TTCTACATACACTTCCATAATGTCATACATCGAGATTTGAAACCTGCCAATATTTTAATC
ACAAAATCTGGAGTCCTCAAACTTACCGATTTTGGCCTTGCTCGCCAAGTTGGTTCTAAA
TATCAAAGCAAGCCTAATTCATTGACAACACGTGTTGTGACTTTGTGGTATCGCGCACCA
GAACTATTGCTTGGTGATCGAAGTTATTCGACTGCTATTGATTTATGGAGTGTTGGTTGT
ATTATGGCTGAAATGTGGACAAGACATGCAATTATGAAAGGTGAAAGTGAAGTGAAGCAA
TTAGAAATATGTGAAAATTGGTGTGGAAACATTTGTCCTCAAAGCTGGCCGGGAGTTGAA
AAATTAGAGCTCTTTCAAAAATTAAACTTTTCCAAAGGTGATCAAAAAAGAAAAGTTAAG
GAGAGACTTAGAGCAGTAGTGAAAGATTCAGCTGCTTTAGAATTAATTGATAATTTATTG
TCACTTGATCCAAAGAACAGAATTGATGCAGATAATGCATTGAATCATGATTATTTTTGG
TCTGATCCAATGCCATGTGAGGACTTGAAGGAAAAATTTGAGAAAATTTCGGATTCGCAT
TTTGAGTTTTTGGATGAGGCAAGACGAAAGAGAGAAGAATTTGAGATGAGAAAATTACTT
GAGAGCAAAAAGAAGAATGGTGTTAACTATAATGGCTATTTTGATAGAGTTTATTAG
>g17533.t1 Gene=g17533 Length=438
MVIISTQKHQTATVSSKMSEYHNKAHLKRLQNGVNINRHLQPAQRQNKISNLPQFRQALA
HEHPNLPRDNIKLSPNMPPTPPPSPEMSKYERILKIGQGTFGEVYKVKSKYDNQILAMKS
IKYKERAEGLPINLVREIKILKQTDNKNIIKLVDVFQHFNNIHLVLEFCHHDLAGILSNQ
RISFKPSEIKSLMKQLMNALFYIHFHNVIHRDLKPANILITKSGVLKLTDFGLARQVGSK
YQSKPNSLTTRVVTLWYRAPELLLGDRSYSTAIDLWSVGCIMAEMWTRHAIMKGESEVKQ
LEICENWCGNICPQSWPGVEKLELFQKLNFSKGDQKRKVKERLRAVVKDSAALELIDNLL
SLDPKNRIDADNALNHDYFWSDPMPCEDLKEKFEKISDSHFEFLDEARRKREEFEMRKLL
ESKKKNGVNYNGYFDRVY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g17533.t1 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 81 | 170 | 1.3E-25 |
| 6 | g17533.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 171 | 393 | 6.6E-68 |
| 10 | g17533.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 66 | 85 | - |
| 2 | g17533.t1 | PANTHER | PTHR24056:SF414 | CYCLIN-DEPENDENT KINASE 9 | 85 | 414 | 1.8E-131 |
| 3 | g17533.t1 | PANTHER | PTHR24056 | CELL DIVISION PROTEIN KINASE | 85 | 414 | 1.8E-131 |
| 1 | g17533.t1 | Pfam | PF00069 | Protein kinase domain | 90 | 379 | 1.6E-73 |
| 8 | g17533.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 96 | 119 | - |
| 7 | g17533.t1 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 208 | 220 | - |
| 11 | g17533.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 90 | 379 | 44.895 |
| 9 | g17533.t1 | SMART | SM00220 | serkin_6 | 90 | 379 | 2.4E-93 |
| 4 | g17533.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 87 | 385 | 2.29E-91 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
