General information for g17541.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Chymotrypsinogen A.
Parent gene
- The parent gene g17541 is located on chr_4: 13823627..13824673 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17541 | g17541.t1 | TTS | g17541.t1 | 13823566 | 13823566 |
| chr_4 | g17541 | g17541.t1 | isoform | g17541.t1 | 13823627 | 13824673 |
| chr_4 | g17541 | g17541.t1 | exon | g17541.t1.exon1 | 13823627 | 13823904 |
| chr_4 | g17541 | g17541.t1 | cds | g17541.t1.CDS1 | 13823627 | 13823904 |
| chr_4 | g17541 | g17541.t1 | exon | g17541.t1.exon2 | 13823964 | 13824454 |
| chr_4 | g17541 | g17541.t1 | cds | g17541.t1.CDS2 | 13823964 | 13824454 |
| chr_4 | g17541 | g17541.t1 | exon | g17541.t1.exon3 | 13824522 | 13824673 |
| chr_4 | g17541 | g17541.t1 | cds | g17541.t1.CDS3 | 13824522 | 13824673 |
| chr_4 | g17541 | g17541.t1 | TSS | g17541.t1 | 13824721 | 13824721 |
Sequences
>g17541.t1 Gene=g17541 Length=921
ATGAAGTTGCTTAAATCAATTTTTATTCTATTGCCTTTCATTGGAATTGTATTAGGTGAT
AAGAGTGGAAAGATCGTTGGAGGAAACACAGCAGTCAGAGGTCAATTTCCCTATCATGTT
TTCATTGATGTTTTTGATGGTCAAAGTACGCATATTTGTGGAGGAGCACTAATTCGTTTC
AATTATGTTCTCACTTCTGCTATATGTATTAGGAATTCTCTTGACATAAATCTAATTTTT
GGTAAAATCAATAGACATGAAGGATCTATTAGTGCTAGGTTTCATATCACAAAACGAGAA
CATATCATTATTCACCCGGAGTTTAATTCAACAACATATGCCAATGATTTAGCGTTGCTT
TATCTTGAAGGTTCTGAAACACTTTTACAAGATCCCTATGTTGATATTATTCCGCTGCCA
ACTGAAGAAGATTATCAAGAAGAAGTTGTTGGACTTAGAGGAAATGTGACAGGCTTTGGA
TTAATAAGTGATGATCCACCAAGGCTTGCGACGGAACTTAAATATATTCAATTACCAATC
ATTAGTAATGTGAATTGTCTGCAAACTTATGGAAACTCTATAAGTTGGGAAGATAAATTT
TGTCTTGATGGCACAGAAGGTTCAACATGCATTGGTGATGAAGGTGCACCGTTTGTTGTC
TATCTAAATGGTCGAGATATTTTGGGAGGAATCGGAAGTATTGCACTCACCAACTGCACA
ATTGGACTTCCTACAATTTTCATAAATTTGCTTCCACATCTTGATTGGATTGATGATAAC
ACTTCTCAGCCACCTGATACTGTTCCACCTCCTCAACCTGATGATAGATGCAATTGTGTT
TGCAGATGCTACACTTGTCCAGCTCCATCAGCTGAATCAACAAACAAGAACATCTTTAAA
AAACGTTGGTTAGAAAATTAA
>g17541.t1 Gene=g17541 Length=306
MKLLKSIFILLPFIGIVLGDKSGKIVGGNTAVRGQFPYHVFIDVFDGQSTHICGGALIRF
NYVLTSAICIRNSLDINLIFGKINRHEGSISARFHITKREHIIIHPEFNSTTYANDLALL
YLEGSETLLQDPYVDIIPLPTEEDYQEEVVGLRGNVTGFGLISDDPPRLATELKYIQLPI
ISNVNCLQTYGNSISWEDKFCLDGTEGSTCIGDEGAPFVVYLNGRDILGGIGSIALTNCT
IGLPTIFINLLPHLDWIDDNTSQPPDTVPPPQPDDRCNCVCRCYTCPAPSAESTNKNIFK
KRWLEN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g17541.t1 | CDD | cd00190 | Tryp_SPc | 25 | 260 | 1.88041E-42 |
| 8 | g17541.t1 | Gene3D | G3DSA:2.40.10.10 | - | 19 | 263 | 8.6E-46 |
| 2 | g17541.t1 | PANTHER | PTHR24260 | - | 22 | 263 | 1.3E-44 |
| 5 | g17541.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 54 | 69 | 3.8E-7 |
| 4 | g17541.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 112 | 126 | 3.8E-7 |
| 3 | g17541.t1 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 207 | 219 | 3.8E-7 |
| 1 | g17541.t1 | Pfam | PF00089 | Trypsin | 25 | 257 | 3.7E-33 |
| 10 | g17541.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 11 | g17541.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 12 | g17541.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 14 | - |
| 13 | g17541.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 19 | - |
| 9 | g17541.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 306 | - |
| 16 | g17541.t1 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 25 | 262 | 22.462 |
| 15 | g17541.t1 | SMART | SM00020 | trypsin_2 | 24 | 257 | 1.0E-26 |
| 6 | g17541.t1 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 8 | 262 | 5.06E-54 |
| 7 | g17541.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
