General information for g17554.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ferrochelatase, mitochondrial.
Parent gene
- The parent gene g17554 is located on chr_4: 13854639..13855949 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17554 | g17554.t6 | TSS | g17554.t6 | 13854161 | 13854161 |
| chr_4 | g17554 | g17554.t6 | isoform | g17554.t6 | 13854247 | 13855949 |
| chr_4 | g17554 | g17554.t6 | exon | g17554.t6.exon1 | 13854247 | 13854626 |
| chr_4 | g17554 | g17554.t6 | cds | g17554.t6.CDS1 | 13854281 | 13854626 |
| chr_4 | g17554 | g17554.t6 | exon | g17554.t6.exon2 | 13854683 | 13854963 |
| chr_4 | g17554 | g17554.t6 | cds | g17554.t6.CDS2 | 13854683 | 13854963 |
| chr_4 | g17554 | g17554.t6 | exon | g17554.t6.exon3 | 13855049 | 13855949 |
| chr_4 | g17554 | g17554.t6 | cds | g17554.t6.CDS3 | 13855049 | 13855066 |
| chr_4 | g17554 | g17554.t6 | TTS | g17554.t6 | 13855928 | 13855928 |
Sequences
>g17554.t6 Gene=g17554 Length=1562
ATGATGCGCCACACTATTCAAAAATTCCCAATAAATGGTAAATAAATTAAATTTTCAATT
GACATTCTTTAGAATCATGGAAATTTGTAAATTTAAAATTTCAGGATGGATGATTAGTAG
AAATTTTTCCTTATCAGCAACGATGTGTGATAACCCTAAGCCAAAAACAGGAATTTTGAT
GTTAAACATGGGTGGACCGCAGACTACAGATCAAGTTGGCGATTACCTTCGGCGCATTAT
GACTGACCGTGATATGATGCAATTACCATTCCAAGATACTTTAGGACCATTTATTGCAAA
AAGAAGAACATCAGAAGTGCAAAAGAAATATCAAGAAATAGGAGGCGGAAGTCCAATTTT
AAAATGGACTAAATTACAAGGTGAACTAATGTGCAAAAAACTCGATCAACTTTCACCTGA
AACTGCTCCTCATAAAAGTTATGTTGGTTTTCGTTACGTTGATCCATTCACTGAAGATAC
TATCAAACAAATTGAAGCTGATGGACCAGAGCGTGTTGTTATTTTCTCTCAATATCCACA
ATATAGTTGTGCAACATCAGGTTCAAGTTTTAATTCAATATATACTCATTTCAATGGACA
AAAACCTAAGAGTAGTATCAAGTGGAGTATGATTGACAGATGGCCAACTCATCAACTTCT
TCTCACTCACTGCCATTAAAATCAGTAAGACGAGGTGATCCATATCCAAATGAAGTAGGA
GCAACTGTTAACGCTGTAATGGCTGAACTTGATTACTGTAATCCATACAGTCTCGTTTGG
CAATCGAAGGTGGGACCTCTGCCCTGGCTTGAGCCATTCACTGACGATGCCATCAAAATG
TATGTCGCTAAGGGCAAGAAACATTTTATTCTTGTTCCCATAGCTTTTGTAAACGAGCAC
ATTGAGACACTTCATGAATTGGACATTGAATACTGTAAAGATCTTGCTAAAGAAATCAGA
GCAGAGAAAATATTGCGAGCAGCAGCACCTAACGATCATCCAATCTTTATCGATGCAATT
AGTGATATTGTAAACAAGCATTTAAAGAGCGATCAAAGAGTTAATCCGAAATTTTTGACT
CGCTGTCCTCACTGTGTTAGCGAGAAATGTCACAAGAGCAAGAAATTCTTTAAAGAGTTG
TGTGAGGCCAGTGTGAATCTCTCAATTTGATTTTTTAATCTAAATATTTTTACACTTCTT
TGAAAACAATACCTCATACAAAAAACGGGTCAAATTTATGTTTCTTTTTCTGTTAGAATT
CTAAAAATTCATCAGTTTACAAACGCTCTTTAAAGAATTTCTTTTTATTTCAAATCGAAT
TTGTAAAACAAATGACAAATGATCAACTCAACTCATAGCATTCTAGAAATTTCTGTGTTA
ATTTTTTTCCTTTAGAAATAGACAATTTAATTGTCCCTTGATTTTTTTTTATATCTGTTC
CTTACGCAAGCAGCTTGCATTTTTTTGTTAGAAAATTTTTATTTTGTTTTATGAACACAC
ACCATGAAAAGACCATATAAATAAATTTTTATGAAAAATGTACCCGATTATTTTTTTTTA
CT
>g17554.t6 Gene=g17554 Length=214
MVNKLNFQLTFFRIMEICKFKISGWMISRNFSLSATMCDNPKPKTGILMLNMGGPQTTDQ
VGDYLRRIMTDRDMMQLPFQDTLGPFIAKRRTSEVQKKYQEIGGGSPILKWTKLQGELMC
KKLDQLSPETAPHKSYVGFRYVDPFTEDTIKQIEADGPERVVIFSQYPQYSCATSGSSFN
SIYTHFNGQKPKSSIKWSMIDRWPTHQLLLTHCH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g17554.t6 | CDD | cd03411 | Ferrochelatase_N | 45 | 206 | 0 |
| 5 | g17554.t6 | Gene3D | G3DSA:3.40.50.1400 | - | 39 | 214 | 0 |
| 2 | g17554.t6 | PANTHER | PTHR11108:SF1 | FERROCHELATASE, MITOCHONDRIAL | 40 | 210 | 0 |
| 3 | g17554.t6 | PANTHER | PTHR11108 | FERROCHELATASE | 40 | 210 | 0 |
| 1 | g17554.t6 | Pfam | PF00762 | Ferrochelatase | 44 | 210 | 0 |
| 4 | g17554.t6 | SUPERFAMILY | SSF53800 | Chelatase | 42 | 210 | 0 |
| 6 | g17554.t6 | TIGRFAM | TIGR00109 | hemH: ferrochelatase | 42 | 210 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004325 | ferrochelatase activity | MF |
| GO:0006783 | heme biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
