General information for g17573.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Pterin-4-alpha-carbinolamine dehydratase.
Parent gene
- The parent gene g17573 is located on chr_4: 13958900..13972173 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17573 | g17573.t5 | TSS | g17573.t5 | 13957845 | 13957845 |
| chr_4 | g17573 | g17573.t5 | isoform | g17573.t5 | 13957867 | 13958582 |
| chr_4 | g17573 | g17573.t5 | exon | g17573.t5.exon1 | 13957867 | 13957918 |
| chr_4 | g17573 | g17573.t5 | cds | g17573.t5.CDS1 | 13957867 | 13957918 |
| chr_4 | g17573 | g17573.t5 | exon | g17573.t5.exon2 | 13958070 | 13958176 |
| chr_4 | g17573 | g17573.t5 | cds | g17573.t5.CDS2 | 13958070 | 13958176 |
| chr_4 | g17573 | g17573.t5 | exon | g17573.t5.exon3 | 13958239 | 13958420 |
| chr_4 | g17573 | g17573.t5 | cds | g17573.t5.CDS3 | 13958239 | 13958420 |
| chr_4 | g17573 | g17573.t5 | exon | g17573.t5.exon4 | 13958478 | 13958582 |
| chr_4 | g17573 | g17573.t5 | cds | g17573.t5.CDS4 | 13958478 | 13958580 |
| chr_4 | g17573 | g17573.t5 | TTS | g17573.t5 | 13958726 | 13958726 |
Sequences
>g17573.t5 Gene=g17573 Length=446
ATGCAATCTGTATTCAAGGTTTTCAAACCAGTTGCATTTCTTCATTTAAAAAGTTGTATT
AGTCACCAATCATGGTTCATTAACAATCATGTAAAAACAACATTATTTTTGAAACCTGAT
TTCACTTTGCAACGTCAATTCAGTAAGAAAACAAAAATGGCAAAGTTGACAGAACAAGAA
CGTGCTGAGTTATTAGAACCACTTTTGAAAACTGGTTGGTCAATGGTTAAAGGACGTGAT
GCAATTTATAAGGAATTTATGTTTAAGAATTTTAATGAAGCGTTTGGTTTCATGAGTCGG
GTTGCTTTGCTTGCTGATAAAATGGATCATCACCCGGAATGGTTTAACGTGTATAATAAA
GTTCAGGTAACAATGTCAACTCATGATTGTGGTGGTCTGAGCACTCGTGATATTAAAGTT
GCTACATTTATGAATGACATTACCAA
>g17573.t5 Gene=g17573 Length=148
MQSVFKVFKPVAFLHLKSCISHQSWFINNHVKTTLFLKPDFTLQRQFSKKTKMAKLTEQE
RAELLEPLLKTGWSMVKGRDAIYKEFMFKNFNEAFGFMSRVALLADKMDHHPEWFNVYNK
VQVTMSTHDCGGLSTRDIKVATFMNDIT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g17573.t5 | CDD | cd00914 | PCD_DCoH_subfamily_b | 72 | 147 | 0.00000 |
| 6 | g17573.t5 | Gene3D | G3DSA:3.30.1360.20 | - | 49 | 148 | 0.00000 |
| 4 | g17573.t5 | Hamap | MF_00434 | Putative pterin-4-alpha-carbinolamine dehydratase. | 53 | 148 | 23.95556 |
| 2 | g17573.t5 | PANTHER | PTHR12599:SF13 | PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE | 51 | 147 | 0.00000 |
| 3 | g17573.t5 | PANTHER | PTHR12599 | PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE | 51 | 147 | 0.00000 |
| 1 | g17573.t5 | Pfam | PF01329 | Pterin 4 alpha carbinolamine dehydratase | 55 | 146 | 0.00000 |
| 5 | g17573.t5 | SUPERFAMILY | SSF55248 | PCD-like | 53 | 147 | 0.00000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008124 | 4-alpha-hydroxytetrahydrobiopterin dehydratase activity | MF |
| GO:0006729 | tetrahydrobiopterin biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K01724 (4a-hydroxytetrahydrobiopterin dehydratase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
