General information for g17573.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as hypothetical.
Parent gene
- The parent gene g17573 is located on chr_4: 13958900..13972173 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17573 | g17573.t8 | TSS | g17573.t8 | 13958237 | 13958237 |
| chr_4 | g17573 | g17573.t8 | isoform | g17573.t8 | 13958883 | 13959981 |
| chr_4 | g17573 | g17573.t8 | exon | g17573.t8.exon1 | 13958883 | 13958930 |
| chr_4 | g17573 | g17573.t8 | exon | g17573.t8.exon2 | 13959022 | 13959255 |
| chr_4 | g17573 | g17573.t8 | cds | g17573.t8.CDS1 | 13959039 | 13959255 |
| chr_4 | g17573 | g17573.t8 | exon | g17573.t8.exon3 | 13959313 | 13959981 |
| chr_4 | g17573 | g17573.t8 | cds | g17573.t8.CDS2 | 13959313 | 13959758 |
| chr_4 | g17573 | g17573.t8 | TTS | g17573.t8 | 13959980 | 13959980 |
Sequences
>g17573.t8 Gene=g17573 Length=951
TTAGTAATTTTTTCAAGCGTAACAATTTTCTTTCGTGGACCAATCGAAGAATGAGAATCC
CGTATATGAAAATTTTAGTTTATATTCTCACTTTCGCGGGATATTGTTATTCCGGTTATG
GAAGTGGTATGTTAAAATCATTAAGAGATGCTGTCCTCAGTGCTGAATTTATATTTGGTG
ATTTCTTTAAGAATTTCATAACTCTTAGTAAAAAATTTCAATCAGTTCATGAGATTTTTG
ATACAGCTGTAGAAGAAAATTGTGTTTTTAAATGTCCTGGAAATCCCGACATAAGGCCTA
AACCAAATAAACTTCATGTACCATCAAGTGATTCTTGTGGTTCACTTGGATTGAAAATTA
ATACCGATTATTTACCAGCACCAGAGATGGCAAAATGCTGTGATGCTCATGACATTTGCT
ATGAGACATGTATTAGTGGCAAAGAATTATGTGATCTTGATTTTAAAAGATGCTTATATA
AGTACTGTGACAGCTTTGAAAAAAGCGCTGCTGGTGAACTGCTGATTAAAGGATGTAAAG
CAGCAGCCAAAACATTATTTACTGGTACAATGGTACTTGGCTGTAAAAGTTATCTTGATG
CACAAGCAAGAGCATGCTATTGTCCAGTGAATCAGAATCAAAATGAACAAAATCAAAGAA
AATATGATAAATATGAATACAAACAAAAACAAAAAGATAAAAAATTTAAATGGCAAAGTG
ATTTATGAATTGATTACAAGAATTTTATATGCGTAATTTTCTTACTGGATCGTAAAGTCA
AATAAATAAAACTTCCTCATTCATGCCTTTATATCAACCTTTTTGCGATATCAACATAAA
CAAATCCATTAAGTATTTATAAAATACCATGACGAACTCATTTTTAAAAAAATTGTTTTA
AATGATTTCCTTTGATGAGGCCTAAAATAAAGAATTTACTAAAAAATAAAA
>g17573.t8 Gene=g17573 Length=220
MKILVYILTFAGYCYSGYGSGMLKSLRDAVLSAEFIFGDFFKNFITLSKKFQSVHEIFDT
AVEENCVFKCPGNPDIRPKPNKLHVPSSDSCGSLGLKINTDYLPAPEMAKCCDAHDICYE
TCISGKELCDLDFKRCLYKYCDSFEKSAAGELLIKGCKAAAKTLFTGTMVLGCKSYLDAQ
ARACYCPVNQNQNEQNQRKYDKYEYKQKQKDKKFKWQSDL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g17573.t8 | PANTHER | PTHR12824:SF8 | GXIVSPLA2, ISOFORM A | 17 | 199 | 1.0E-41 |
| 3 | g17573.t8 | PANTHER | PTHR12824 | GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER | 17 | 199 | 1.0E-41 |
| 1 | g17573.t8 | Pfam | PF06951 | Group XII secretory phospholipase A2 precursor (PLA2G12) | 15 | 191 | 4.5E-48 |
| 7 | g17573.t8 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 16 | - |
| 8 | g17573.t8 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 9 | g17573.t8 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 11 | - |
| 10 | g17573.t8 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 12 | 16 | - |
| 6 | g17573.t8 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 17 | 220 | - |
| 5 | g17573.t8 | ProSitePatterns | PS00118 | Phospholipase A2 histidine active site. | 111 | 118 | - |
| 4 | g17573.t8 | SUPERFAMILY | SSF48619 | Phospholipase A2, PLA2 | 77 | 172 | 3.51E-15 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0050482 | arachidonic acid secretion | BP |
| GO:0016042 | lipid catabolic process | BP |
| GO:0006644 | phospholipid metabolic process | BP |
| GO:0005509 | calcium ion binding | MF |
| GO:0005576 | extracellular region | CC |
| GO:0004623 | phospholipase A2 activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01047 (secretory phospholipase A2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
