General information for g17592.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Atrial natriuretic peptide receptor 1.
Parent gene
- The parent gene g17592 is located on HiC_scaffold_8: 1..10534 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| HiC_scaffold_8 | g17592 | g17592.t1 | isoform | g17592.t1 | 1 | 10534 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon1 | 1320 | 1397 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS1 | 1320 | 1397 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon2 | 1487 | 1866 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS2 | 1526 | 1866 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon3 | 1929 | 1980 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS3 | 1929 | 1980 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon4 | 2168 | 2198 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS4 | 2168 | 2198 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon5 | 2293 | 2450 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS5 | 2293 | 2450 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon6 | 2515 | 2565 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS6 | 2515 | 2565 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon7 | 2636 | 2663 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS7 | 2636 | 2663 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon8 | 7251 | 7371 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS8 | 7251 | 7371 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon9 | 7441 | 7469 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS9 | 7441 | 7469 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon10 | 7534 | 7623 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS10 | 7534 | 7623 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon11 | 8189 | 8265 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS11 | 8189 | 8265 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon12 | 8487 | 8630 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS12 | 8487 | 8630 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon13 | 8698 | 9082 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS13 | 8698 | 9082 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon14 | 9158 | 9482 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS14 | 9158 | 9482 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon15 | 9533 | 10087 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS15 | 9533 | 10087 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon16 | 10183 | 10401 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS16 | 10183 | 10401 |
| HiC_scaffold_8 | g17592 | g17592.t1 | exon | g17592.t1.exon17 | 10459 | 10534 |
| HiC_scaffold_8 | g17592 | g17592.t1 | cds | g17592.t1.CDS17 | 10459 | 10534 |
| HiC_scaffold_8 | g17592 | g17592.t1 | TSS | g17592.t1 | NA | NA |
| HiC_scaffold_8 | g17592 | g17592.t1 | TTS | g17592.t1 | NA | NA |
Sequences
>g17592.t1 Gene=g17592 Length=2799
CCACCCGAGCAAGGAGAGCTAACAGTCACATCCGGAATACTTGGGAGAATCACACAAAAA
TGGAAAAATGAAAGCTCTTTTTTTAAAGATAAATCACGGTATGCCACTCTAACTAGGATG
TCTTATTGCCAATGCAGATTGAAGCTCGTTTTCAAAAGCATTTTCAAAGAATTTGGTTTC
AAGCATGTCGCGTTACTTCTCGATCGTTCAGATTTATTTTCACTGACAGTTGGAAAAAAT
TTAGAATACGGCTTAAAAGAAGATGGAGTTCTAAAATTGGTAAAAGAATTGAATGGCAAT
GAACTACTTTTGCCAGGAGGAAAACTCAACAAGTCTGAGAGTGATAAGCTAATGAAAGAT
CTTACGACATATTTGCGTGACGCATCAATGTATGCGCGAGTTATTATTTTGTCAGTTCGA
GGACAACTTGTGAGACAATTTATGCTTGCTGCGTATCACCTTGGCATGACAAAAGGTGAT
TACACTTTTCTAGATGTCGAGATTTTTCAAAGTTCTTATTGGTCTGATCATTATTGGGAA
GAGGACGATGAGAATGATTTGATAGCGAGAAAAGCTTTTGAAGCTCTCTTACGAGTTTCG
CTTCTTCAACCAACCAGTCCGAAATTCAATCAATTTGCTGAGAATGTAAGGGAGCGTGCT
AAACGTGACTATGGATATTCCTTTTATGAGGGTGAAGAGGTAAATTTCTTCATTGGAGCA
TTTTACGATGGTGTATTATTACTTGGCATGGTTTTAAATGAGACACTAACTGAAGGAGGG
ATAACTGGAACAGTTCGGATCGATGATAATGGTGATAGAGATGCTGATTATTCGCTTCTA
GATTTAGATCCTGTTACAGGAAGATTTGAAGTTGTTTCTCATTATTATGGTTCAAATAGC
AGAAGTTTAGTGCCAGTTCAAGGAAAACACATTCATTGGCCTGGATCGCTTGATGGACCT
CCAGCTGATGTTCCGGCATGTGGCTTTCTAGGAAACGATCCGAATTGTCAAGGAAATGTT
AAACCGGATGATGTACTTATTGAAGTTGGAAGACTTTTTGGATCTAAAATTGGCCTTCAA
AAATTAAATTATGAGAATTTTTCAATAAATCAACTTGGTGTGAGCAGTGGTCGTGGTTCA
ATAGCAAGCCTTGGCAGTATAGCTCCATCTCAAGAATCAATTACAATAGGTGTTTTTAGA
GGCGAAAGAGTCGCAATAAAGAAAATTCTTAAGAAAAAGGTTGTCGTTGATACTACGTTG
TTATGGGAGATAAAAAAAACTCGAGATGTTAATCATGAAAATACAAATCGATTTATTGGT
GCTTGCATTGATTTGCCTTACTCATGTTCTTGCGTTCTCATATTGTCCGAATATTGTCCC
AAAACACTCAAGGAAGTGCTCGAGAATGAAGCCATTCAACTTGATTGGAATTTTCGAATG
TCGCTCATTCATGACCTTGTAAAAGGCATGGCTTATTTGCACAATAGTGATGTCTCGGTT
CATGGTAAATTGAGGTCGAGTAATTGCCTTATCGATGGACGATTTGTTCTCAAAATATCT
GATTTTGGTTTAAGAACATTGACAATGCCTTCAGAGTTTGTCAAGGATCAAACTTATTAT
CACAAGCTATTATGGGTAGCACCGGAACTTCTTCCAATAACCATTATAGCAGGAACGCCT
GCAACACAAAAAGGCGATGTTTATTCATTTTCTATAATCCTCGAGGAAATAGTTGTGCGT
GGAGGTCCTTACGAAACAGTCAAATACATGACAATCAATCAAATTCTTGATCGTGTAGCT
GCTCATGACAATCCACCTTTTAGGCCACTCATTGGAGAGCGTGATTGCCCATCAGAATTA
GTTGATTTAATGGAGAAATGTTGGAATGATAATCCTGATGAACGTCCATCATTTGCAAAT
ATTAAGACAACTGTCTCATGCATTATGAAAGGTTTTTGTGAAAATTTAATGGATGATTTA
TTACGCCGCATGCAACATTACGCAAACAACTTAGAAAGTCTTGTCGAAGAAAAGACGGAG
CAATTGAGCATGGAAAAGCGTCGTACAGAAGAGTTACTCTATCAAGTGTTACCAAAGAGT
GTCGCATTGACTTTACTCTCGGGAGAAATGGTTCAACCAGAACAATTCGAATGCGTGACC
ATTTATTTCAGTGACATTTGTGGCTTTACTGCTTTGTGTGCTCAATCAAATCCAATTGAA
GTTGTAGACTTTTTGAATGATCTTTATAGTACCTTTGATAGAATTATTGGTTTTTACGAT
GTTTATAAAGTAGAGACAATTGGTGATGCTTATATGTGTGTTTCTGGTTTACCTGAACGA
AATGGAGATGACCATGCAAGGGAAATAGGATTAATGGCGTTATCAATTCTTGATGCAGTA
AAAAGTTTTACAATTAAACATAAGCCTGAATATCAATTAAAAATTCGAATTGGGATCAAT
TCTGGCAGTGTTTGTGCAGGCGTTGTAGGACAAAAAATGCCTCGCTATTGTCTCTTTGGT
GATGTTGTAAACACCGCAAGTCGTCTCGAATCGACAGGCGAGCCGCTAAAAATACACGTT
TCACAGGCAACAAAGATTATTTTTGACAAATTCGGCACGTTTCAATTGGAATTACGTGGC
GATATTGAGCTGAAAGGAAAGGGAAAAGTTACGACATACTGGTTATGTGGTTGCTCTGAA
AAAGATCCACGGCAAGTTGCTAAACCACCTACTCCACTCAAGAATCATGTTGACACTGAA
GCAAATCCATTTCCGATTTTATTTCCATCTATTAAATAA
>g17592.t1 Gene=g17592 Length=932
PPEQGELTVTSGILGRITQKWKNESSFFKDKSRYATLTRMSYCQCRLKLVFKSIFKEFGF
KHVALLLDRSDLFSLTVGKNLEYGLKEDGVLKLVKELNGNELLLPGGKLNKSESDKLMKD
LTTYLRDASMYARVIILSVRGQLVRQFMLAAYHLGMTKGDYTFLDVEIFQSSYWSDHYWE
EDDENDLIARKAFEALLRVSLLQPTSPKFNQFAENVRERAKRDYGYSFYEGEEVNFFIGA
FYDGVLLLGMVLNETLTEGGITGTVRIDDNGDRDADYSLLDLDPVTGRFEVVSHYYGSNS
RSLVPVQGKHIHWPGSLDGPPADVPACGFLGNDPNCQGNVKPDDVLIEVGRLFGSKIGLQ
KLNYENFSINQLGVSSGRGSIASLGSIAPSQESITIGVFRGERVAIKKILKKKVVVDTTL
LWEIKKTRDVNHENTNRFIGACIDLPYSCSCVLILSEYCPKTLKEVLENEAIQLDWNFRM
SLIHDLVKGMAYLHNSDVSVHGKLRSSNCLIDGRFVLKISDFGLRTLTMPSEFVKDQTYY
HKLLWVAPELLPITIIAGTPATQKGDVYSFSIILEEIVVRGGPYETVKYMTINQILDRVA
AHDNPPFRPLIGERDCPSELVDLMEKCWNDNPDERPSFANIKTTVSCIMKGFCENLMDDL
LRRMQHYANNLESLVEEKTEQLSMEKRRTEELLYQVLPKSVALTLLSGEMVQPEQFECVT
IYFSDICGFTALCAQSNPIEVVDFLNDLYSTFDRIIGFYDVYKVETIGDAYMCVSGLPER
NGDDHAREIGLMALSILDAVKSFTIKHKPEYQLKIRIGINSGSVCAGVVGQKMPRYCLFG
DVVNTASRLESTGEPLKIHVSQATKIIFDKFGTFQLELRGDIELKGKGKVTTYWLCGCSE
KDPRQVAKPPTPLKNHVDTEANPFPILFPSIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 18 | g17592.t1 | CDD | cd07302 | CHD | 719 | 895 | 3.52525E-66 |
| 17 | g17592.t1 | Coils | Coil | Coil | 657 | 688 | - |
| 15 | g17592.t1 | Gene3D | G3DSA:3.40.50.2300 | - | 46 | 236 | 3.0E-31 |
| 16 | g17592.t1 | Gene3D | G3DSA:3.40.50.2300 | - | 266 | 329 | 1.1E-11 |
| 14 | g17592.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 395 | 685 | 4.5E-53 |
| 13 | g17592.t1 | Gene3D | G3DSA:3.30.70.1230 | Adenylyl Cyclase | 705 | 897 | 7.7E-74 |
| 5 | g17592.t1 | PANTHER | PTHR11920 | GUANYLYL CYCLASE | 1 | 339 | 0.0 |
| 7 | g17592.t1 | PANTHER | PTHR11920:SF274 | GUANYLATE CYCLASE | 1 | 339 | 0.0 |
| 4 | g17592.t1 | PANTHER | PTHR11920 | GUANYLYL CYCLASE | 340 | 928 | 0.0 |
| 6 | g17592.t1 | PANTHER | PTHR11920:SF274 | GUANYLATE CYCLASE | 340 | 928 | 0.0 |
| 9 | g17592.t1 | PRINTS | PR00255 | Natriuretic peptide receptor signature | 133 | 151 | 1.4E-5 |
| 8 | g17592.t1 | PRINTS | PR00255 | Natriuretic peptide receptor signature | 241 | 259 | 1.4E-5 |
| 2 | g17592.t1 | Pfam | PF01094 | Receptor family ligand binding region | 24 | 283 | 2.7E-38 |
| 3 | g17592.t1 | Pfam | PF07714 | Protein tyrosine and serine/threonine kinase | 402 | 643 | 2.0E-36 |
| 1 | g17592.t1 | Pfam | PF00211 | Adenylate and Guanylate cyclase catalytic domain | 712 | 895 | 5.1E-65 |
| 21 | g17592.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 370 | 652 | 27.835 |
| 20 | g17592.t1 | ProSiteProfiles | PS50125 | Guanylate cyclase domain profile. | 720 | 850 | 49.206 |
| 19 | g17592.t1 | SMART | SM00044 | cyc_6 | 684 | 878 | 5.7E-103 |
| 10 | g17592.t1 | SUPERFAMILY | SSF53822 | Periplasmic binding protein-like I | 25 | 329 | 1.59E-55 |
| 11 | g17592.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 400 | 689 | 1.68E-48 |
| 12 | g17592.t1 | SUPERFAMILY | SSF55073 | Nucleotide cyclase | 706 | 895 | 1.4E-63 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0009190 | cyclic nucleotide biosynthetic process | BP |
| GO:0006468 | protein phosphorylation | BP |
| GO:0035556 | intracellular signal transduction | BP |
KEGG
Orthology
- This transcript has been annotated with K12323 (atrial natriuretic peptide receptor A)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed