General information for g1783.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Choline O-acetyltransferase.
Parent gene
- The parent gene g1783 is located on chr_3: 12977427..12980121 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1783 | g1783.t1 | isoform | g1783.t1 | 12977427 | 12980121 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon1 | 12977427 | 12977624 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS1 | 12977427 | 12977624 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon2 | 12977828 | 12978028 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS2 | 12977828 | 12978028 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon3 | 12978177 | 12978323 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS3 | 12978177 | 12978323 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon4 | 12978379 | 12978436 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS4 | 12978379 | 12978436 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon5 | 12978490 | 12978612 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS5 | 12978490 | 12978612 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon6 | 12978665 | 12979480 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS6 | 12978665 | 12979480 |
| chr_3 | g1783 | g1783.t1 | exon | g1783.t1.exon7 | 12979973 | 12980121 |
| chr_3 | g1783 | g1783.t1 | cds | g1783.t1.CDS7 | 12979973 | 12980121 |
| chr_3 | g1783 | g1783.t1 | TSS | g1783.t1 | NA | NA |
| chr_3 | g1783 | g1783.t1 | TTS | g1783.t1 | NA | NA |
Sequences
>g1783.t1 Gene=g1783 Length=1692
ATGTACATGGATGTTCCTTTACCGTTACCGATTAACTCTAATCCCGGAATGGTTTTTCCA
CCTAGGAAGTTCACAACTGTACATGACGTTGCACGATTTGCTGCTAGAATTATTGATGGT
ATTCTTGAACATAAGGAACTTCTAGATAGCGGAAATTTACCACAAGAACGTGCAGCATCT
CGTGAAAAGAACCAACCACTCTGTATGGCACAGTATTATCGACTTTTAGGCTCATGTCGT
CGACCTGGTCTTGAAAGAGATTCACAATTTCTTCCTGACGTGCGTAATCGAGACGAAAGC
CATCATATCATTATTTGTTGTCGTAATCAAATGTATTGCGTCGTTGTTCAAGCTAATCAA
ATTGGAAAACTTTCGGAAGATGAAATATTTTCACAATTGCTATACATTCTCAGTGATGCA
CCATGTCTTCCGAGTGCTCCACCTATGATTGGCTTATTAACAGCAGAACCACGTCGTATT
TGGGCAAAAGATCGTCAAGTTTTATTACAAGATGAACAAAATTGTCGAAATATTGAATTA
ATTGAAAAATCATTGATAAATTTGTGTTTAGATGAAACTTTGCCATTGGCATTTAATGCT
AGAGGATTTGTTGGTGCTGCATCAAGTACTCATTTTGCAGGTCATAGAGATGAAACAAAT
ATGGCACATGAAATGATTCATGGAGGCGGAAGTGAATGCAACACTGCAAATCGATGGTTT
GATAAGACCATGCAGATTATAATTTGTAATGATGGCACATGGGGTTTATGTTATGAACAT
TCGACTTCTGAAGGAATTGCAGTTGTGTCATTGTTAGAGAAAATTCTCAACAAAATCGAT
GAAATTCCAAGTCTGGAAGAGAATGGAATTACACAGCAACATTTACCACCACCAGAACGA
CTCGAATGGATTGTCAGACCTGAAATTTCTAAAAGAATTCAAGAAGCAAAACGTGATGTT
GACAGACGCATTGAGGATCTTGATTTTTACGTTTATCGATATCAGACTTATGGCAAAAAC
TTTATAAAATCATGTAGAGTTAGTCCAGATGTTTATATTCAATTAGCATTACAACTGGCT
TACTATAAATTGTATGGCCATTTAGTCAGTACTTATGAAAGCGCATCAACAAGGCGATTT
TTGTTGGGTCGAGTTGATTGCATTCGTTCTGCAAGTATAGAAGCTCTAGAATGGGCAAAA
GCGATGTGTCAAGGTGAAGGTGCAAACGTTGCATTAGAAAGTGACAAAGAAGATGAAGAA
GATTCAAGAAAAGTTTCATTTAGCATTTACAATAGGGAACAACTTACTGAGCTTTTCAGA
ACAGCAGCAACACGTCAAACCGAAATTATGGTGCAAAATATTTTAGGAAATGGCATTGAT
ATTCCATTACTTGGTCTTCGTGAGGCATCACGTGAAATTGATGGTGAATTGCATGAACTT
TTTACAGATGAAAGTTATAAAATTGCAAATTGCTTTTTATTATCAACGAGTCAGGTTGCA
TGTACTACAAATAGTTTTATGGGTTATGGTCCAGTAACACCACGAGGTTATGGTTGCTCT
TACAATCCACATCCAGAAGAAATAATCTTTTGTGTATCAGCATTTTATTCAGCTGACAAT
ACGAGTGCATCACGCTATGCGAAATCATTACAGGAATCACTGGATATTATGAGAGATCTT
TTGGCAAAATAA
>g1783.t1 Gene=g1783 Length=563
MYMDVPLPLPINSNPGMVFPPRKFTTVHDVARFAARIIDGILEHKELLDSGNLPQERAAS
REKNQPLCMAQYYRLLGSCRRPGLERDSQFLPDVRNRDESHHIIICCRNQMYCVVVQANQ
IGKLSEDEIFSQLLYILSDAPCLPSAPPMIGLLTAEPRRIWAKDRQVLLQDEQNCRNIEL
IEKSLINLCLDETLPLAFNARGFVGAASSTHFAGHRDETNMAHEMIHGGGSECNTANRWF
DKTMQIIICNDGTWGLCYEHSTSEGIAVVSLLEKILNKIDEIPSLEENGITQQHLPPPER
LEWIVRPEISKRIQEAKRDVDRRIEDLDFYVYRYQTYGKNFIKSCRVSPDVYIQLALQLA
YYKLYGHLVSTYESASTRRFLLGRVDCIRSASIEALEWAKAMCQGEGANVALESDKEDEE
DSRKVSFSIYNREQLTELFRTAATRQTEIMVQNILGNGIDIPLLGLREASREIDGELHEL
FTDESYKIANCFLLSTSQVACTTNSFMGYGPVTPRGYGCSYNPHPEEIIFCVSAFYSADN
TSASRYAKSLQESLDIMRDLLAK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g1783.t1 | Gene3D | G3DSA:3.30.559.70 | - | 1 | 330 | 1.5E-176 |
| 8 | g1783.t1 | Gene3D | G3DSA:3.30.559.40 | - | 331 | 557 | 1.5E-176 |
| 2 | g1783.t1 | PANTHER | PTHR22589:SF14 | CHOLINE O-ACETYLTRANSFERASE | 1 | 562 | 1.2E-231 |
| 3 | g1783.t1 | PANTHER | PTHR22589 | CARNITINE O-ACYLTRANSFERASE | 1 | 562 | 1.2E-231 |
| 1 | g1783.t1 | Pfam | PF00755 | Choline/Carnitine o-acyltransferase | 1 | 557 | 7.9E-152 |
| 6 | g1783.t1 | ProSitePatterns | PS00440 | Acyltransferases ChoActase / COT / CPT family signature 2. | 238 | 265 | - |
| 4 | g1783.t1 | SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | 1 | 327 | 1.33E-81 |
| 5 | g1783.t1 | SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | 326 | 561 | 7.23E-70 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016746 | acyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00623 (choline O-acetyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed