General information for g1826.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Succinate-semialdehyde dehydrogenase, mitochondrial.
Parent gene
- The parent gene g1826 is located on chr_3: 13206485..13210007 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1826 | g1826.t10 | isoform | g1826.t10 | 13205255 | 13207189 |
| chr_3 | g1826 | g1826.t10 | exon | g1826.t10.exon1 | 13205255 | 13206429 |
| chr_3 | g1826 | g1826.t10 | cds | g1826.t10.CDS1 | 13205471 | 13206429 |
| chr_3 | g1826 | g1826.t10 | exon | g1826.t10.exon2 | 13206479 | 13206553 |
| chr_3 | g1826 | g1826.t10 | cds | g1826.t10.CDS2 | 13206479 | 13206553 |
| chr_3 | g1826 | g1826.t10 | exon | g1826.t10.exon3 | 13206612 | 13206825 |
| chr_3 | g1826 | g1826.t10 | cds | g1826.t10.CDS3 | 13206612 | 13206825 |
| chr_3 | g1826 | g1826.t10 | exon | g1826.t10.exon4 | 13206884 | 13207189 |
| chr_3 | g1826 | g1826.t10 | cds | g1826.t10.CDS4 | 13206884 | 13207189 |
| chr_3 | g1826 | g1826.t10 | TSS | g1826.t10 | 13207183 | 13207183 |
| chr_3 | g1826 | g1826.t10 | TTS | g1826.t10 | NA | NA |
Sequences
>g1826.t10 Gene=g1826 Length=1770
ATGATTAGTCTATCGCAAAGAGTCTTCCAATTTGGAGCAATCAAATTTAATTCTACAAAT
AAGATTCAATTGGTTAGAATGATGCATTCTCTGATTAAAAACCAAGCCTACATTAATGGA
AAGTGGACAAATGCAGCTAACAATAAAACATTTAGTGTAATGAATCCATCAAATCAAGAA
ATAGTTGCACAAGTTCCTGATATGACTAAAATTGATTGTCAAAAAGCAATTGATGCAGCT
AATGATGCATTTTATTCAAAAGAATGGCGTAATGCCACAGCTAAAGATCGATCTACATTA
CTAAAGAAATGGTTTACACTTTTGGAAGCGAATAAACAAGAAATTGCTCAAATAATGACA
ACTGAGAGTGGCAAACCTATTGCTGAAGCGTTAGGAGAAGTAGCTTACGGAAATTCTTTT
GTTGAATGGTTTGCAGAAGAGGCAAGAAGAATTTATGGTGAAATTGTCCCTTCTCCAGTT
GCCAGCAAACAAATTAAAATTGTACGACAACCTATTGGAGTTGCTGGTCTTATCACACCT
TGGAATTTTCCACACGCAATGATAACACGAAAAGCTGCTGCTGCATTAGCTGCAGTAATC
ATTTTAGGTTGCACAGTTGTAATGCGTCCTGCTGAAGACACACCACTTACTGCTCTTGCT
CTTTGTAAATTAGCAGAAGATGCCGGCTTTCCAAAGGGAGTCATAAATTGCGTAACTTCG
AGTCGATCACATGCATCCGAAATTGGTGAACTTTTGTGCAAAAGTCCAAAAGTAGCAGGA
ATTTCATTTACCGGTTCGACTCAAGTTGGAAAACTTTTATATAAACAATGTGGAGAAGGA
GTCAAAAGAATTGGATTAGAATTAGGTGGAAATGCGGCATTTATAGTTTTTGAATCTGCT
AACATTGATCAAGCTGTTGCTGGTGCAATGGCATCAAAATTTAGAAATTGTGGTCAAACA
TGTGTATCATCAAATCGATTCCTAGTTCAAGAAAAAATTTTTGATCAATTTGTTGAGAAA
ATTACTGAACAAGTTAAAGCACTAAAAATCGGTGATGGTACACAATCTGATGTAAAAATT
GGACCATTGATTAATGAAGCACAACTTCATAAAGTATCTGCAATGGTTGATGATGCAAAA
TCAAAAGGTGCTAAAGTCATATATGGTGGTCGAGCATTATCTGAAATTGGCTCACTTTTT
TATGAACCGACAATAATTTCAAATATTCAATCAAATATGGATTTGTATAACGAAGAAGTT
TTTGGACCAGTAATTTCACTAATTAAATTTAAAACAGAAGAAGAAGCATTAAAAATCGCA
AATAGCACACCTAGAGGTCTTGCAGGTTATTTCTATAGTCAAGATATAAATCAAATTTTC
CGTGTCGAAAGAGATCTAGAAGCTGGAATGATTGGAATTAATGAAGGCATCATATCAACA
ACTGAGGCGCCTTTTGGTGGAATAAAAGAATCTGGAATTGGTCGAGAAGGTTCAAAACAT
GGTATCGATGAATACGTTGAAATCAAATATATTTGTTATGGAAATTTAAATTAAATATGT
AAATGCATTTAAATGAATTCCCTGTATTATATGATTGTTATTGTGCATATAAAAATTATA
TAAAATTTAAACAAATAATTTTTATTAAGAACGAGTCTTCCACTAATTTAATTTTAAAAT
AAATGTCAAACACTTCATGAAAAATTACAATATGACTTTTAAGATAATGATATCTTTATA
ATATTGTAATCATTGTTTTATTTGTTTATA
>g1826.t10 Gene=g1826 Length=517
MISLSQRVFQFGAIKFNSTNKIQLVRMMHSLIKNQAYINGKWTNAANNKTFSVMNPSNQE
IVAQVPDMTKIDCQKAIDAANDAFYSKEWRNATAKDRSTLLKKWFTLLEANKQEIAQIMT
TESGKPIAEALGEVAYGNSFVEWFAEEARRIYGEIVPSPVASKQIKIVRQPIGVAGLITP
WNFPHAMITRKAAAALAAVIILGCTVVMRPAEDTPLTALALCKLAEDAGFPKGVINCVTS
SRSHASEIGELLCKSPKVAGISFTGSTQVGKLLYKQCGEGVKRIGLELGGNAAFIVFESA
NIDQAVAGAMASKFRNCGQTCVSSNRFLVQEKIFDQFVEKITEQVKALKIGDGTQSDVKI
GPLINEAQLHKVSAMVDDAKSKGAKVIYGGRALSEIGSLFYEPTIISNIQSNMDLYNEEV
FGPVISLIKFKTEEEALKIANSTPRGLAGYFYSQDINQIFRVERDLEAGMIGINEGIIST
TEAPFGGIKESGIGREGSKHGIDEYVEIKYICYGNLN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g1826.t10 | CDD | cd07103 | ALDH_F5_SSADH_GabD | 53 | 512 | 0.0 |
| 6 | g1826.t10 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 42 | 506 | 9.1E-175 |
| 7 | g1826.t10 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 293 | 483 | 9.1E-175 |
| 2 | g1826.t10 | PANTHER | PTHR43353:SF5 | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL | 28 | 515 | 8.8E-214 |
| 3 | g1826.t10 | PANTHER | PTHR43353 | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL | 28 | 515 | 8.8E-214 |
| 1 | g1826.t10 | Pfam | PF00171 | Aldehyde dehydrogenase family | 42 | 511 | 9.3E-165 |
| 5 | g1826.t10 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 286 | 293 | - |
| 4 | g1826.t10 | SUPERFAMILY | SSF53720 | ALDH-like | 22 | 515 | 9.42E-162 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00139 (succinate-semialdehyde dehydrogenase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
