General information for g1826.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein unc-13 homolog 4B.
Parent gene
- The parent gene g1826 is located on chr_3: 13206485..13210007 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1826 | g1826.t2 | TTS | g1826.t2 | 13199737 | 13199737 |
| chr_3 | g1826 | g1826.t2 | isoform | g1826.t2 | 13199976 | 13201299 |
| chr_3 | g1826 | g1826.t2 | exon | g1826.t2.exon1 | 13199976 | 13200073 |
| chr_3 | g1826 | g1826.t2 | cds | g1826.t2.CDS1 | 13199976 | 13200073 |
| chr_3 | g1826 | g1826.t2 | exon | g1826.t2.exon2 | 13200139 | 13200332 |
| chr_3 | g1826 | g1826.t2 | cds | g1826.t2.CDS2 | 13200139 | 13200332 |
| chr_3 | g1826 | g1826.t2 | exon | g1826.t2.exon3 | 13200389 | 13201299 |
| chr_3 | g1826 | g1826.t2 | cds | g1826.t2.CDS3 | 13200389 | 13201170 |
| chr_3 | g1826 | g1826.t2 | TSS | g1826.t2 | NA | NA |
Sequences
>g1826.t2 Gene=g1826 Length=1203
GAGACAGTTTACGAAAAGAAATTTCAAGTTACTCCTGAATGGTGTCTTGCAATTAATAAT
ATTGATTATATTCGTCAAAGCATTCATTCATTTGTGAAAGAATTGGGCGTTGATGAGATA
ATAAGAAATATGAGTGACTTTAGAGGACCACTTGATGCACAAAGATGCTCTGATACATTA
CAGAATGTTATTGAAAATGCCATAGATACGGGTAAAAACAAAATTTTCGAATTAACAGCA
AAACTTGCACGTAAAATGAGTCCAGCAATGCGTCGATTCCTAGTGGAAGGTGCAGAACTG
TTTGAAACAGATTCAAATTCGATGGATCGACTTATGATGTACATGGAAGATTCACTTAAG
ACACTTCATACTGAATTAAATGATGATAATTTCATGAGAATGTTGGATTGCATTTGGGAA
GAAATTGCAAGTATTCTCTATGACCTTGTTCACAGTAGCTTGGACAAGAGGCGTCCGCCT
GCATTTTATGCCAATTTGCGTGCAACTTTGCAAGTTATGGTGGAAAATTTCAAGTGCCAA
AATACAACTGAGCCTGTCAAGTCAAGCGATAAAGAGACGTTAGAGAAAATAGACAGACTT
CTTGAAATTCACAGCTTAGAAACAACTGATCTCATTCATCAGTATTATAAAGATCGATAT
GCAATGCAGCAAGCCATGGGAGATTCAATGCCTTATGGCATTCTCACAATTCAATGTTAT
TTTCAACGCAATACATTAGAAATTGAAGTGATGAATGCAAAACATTTATTGCCGATGAAT
GCTGATGGAACATGTGATCCTTTCGTTAGAATACATTTTTATCCAGAAGATAAATTTATT
GGCATTTCACCACCCAAGACTAAAGTCCATCAAAAGACACTTTTTCCGCTTTTCGATGAA
AAGTTTACAATTCAATTGAATGATGATCAGCGTAAAATGGACGAAGCTATAATTTTGTTT
AGTGTTAAAGATCATGATTATTTTGGAATGGCAAACCAATATGTTGCTGAGGCTTTTCTT
ATGTTCAAAGACATAGCTGATATTACTGGTGAAACTGGAAGCATCAAACAGTTGCATTTA
ACACTTACACGACCACAAAATGACGATATGGAGACAGTTAAAGCATTACAACATCGAGTT
GGTGACAAATTGGCTAAAGAATTTTTAAAGAAGCTTAAGACAAAAAAAACGGAAGCAAAA
TGA
>g1826.t2 Gene=g1826 Length=357
MSDFRGPLDAQRCSDTLQNVIENAIDTGKNKIFELTAKLARKMSPAMRRFLVEGAELFET
DSNSMDRLMMYMEDSLKTLHTELNDDNFMRMLDCIWEEIASILYDLVHSSLDKRRPPAFY
ANLRATLQVMVENFKCQNTTEPVKSSDKETLEKIDRLLEIHSLETTDLIHQYYKDRYAMQ
QAMGDSMPYGILTIQCYFQRNTLEIEVMNAKHLLPMNADGTCDPFVRIHFYPEDKFIGIS
PPKTKVHQKTLFPLFDEKFTIQLNDDQRKMDEAIILFSVKDHDYFGMANQYVAEAFLMFK
DIADITGETGSIKQLHLTLTRPQNDDMETVKALQHRVGDKLAKEFLKKLKTKKTEAK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g1826.t2 | CDD | cd04009 | C2B_Munc13-like | 188 | 320 | 0.000 |
| 6 | g1826.t2 | Gene3D | G3DSA:2.60.40.150 | - | 183 | 321 | 0.000 |
| 2 | g1826.t2 | PANTHER | PTHR45999:SF2 | PROTEIN UNC-13 HOMOLOG 4B | 2 | 353 | 0.000 |
| 3 | g1826.t2 | PANTHER | PTHR45999 | UNC-13-4A, ISOFORM B | 2 | 353 | 0.000 |
| 1 | g1826.t2 | Pfam | PF00168 | C2 domain | 202 | 309 | 0.000 |
| 8 | g1826.t2 | ProSiteProfiles | PS51259 | Munc13-homology domain 2 (MHD2) profile. | 62 | 172 | 15.184 |
| 7 | g1826.t2 | ProSiteProfiles | PS50004 | C2 domain profile. | 201 | 296 | 13.949 |
| 5 | g1826.t2 | SMART | SM00239 | C2_3c | 202 | 311 | 0.000 |
| 4 | g1826.t2 | SUPERFAMILY | SSF49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | 191 | 302 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
