General information for g1841.t22
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform.
Parent gene
- The parent gene g1841 is located on chr_3: 13260701..13261369 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1841 | g1841.t22 | TTS | g1841.t22 | 13254002 | 13254002 |
| chr_3 | g1841 | g1841.t22 | isoform | g1841.t22 | 13254268 | 13261189 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon1 | 13254268 | 13254402 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon2 | 13254475 | 13254633 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon3 | 13258760 | 13258857 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon4 | 13258945 | 13259081 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon5 | 13259252 | 13259406 |
| chr_3 | g1841 | g1841.t22 | cds | g1841.t22.CDS1 | 13259305 | 13259406 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon6 | 13259461 | 13259657 |
| chr_3 | g1841 | g1841.t22 | cds | g1841.t22.CDS2 | 13259461 | 13259657 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon7 | 13259736 | 13259905 |
| chr_3 | g1841 | g1841.t22 | cds | g1841.t22.CDS3 | 13259736 | 13259905 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon8 | 13260718 | 13260886 |
| chr_3 | g1841 | g1841.t22 | cds | g1841.t22.CDS4 | 13260718 | 13260812 |
| chr_3 | g1841 | g1841.t22 | exon | g1841.t22.exon9 | 13261177 | 13261189 |
| chr_3 | g1841 | g1841.t22 | TSS | g1841.t22 | 13261336 | 13261336 |
Sequences
>g1841.t22 Gene=g1841 Length=1233
TCTCGTCGGCCAAGTAAAAAGGAAGATCTTTTGGGATAGTTTGTAATCATTTGAGTAGCC
ATTAAGTCTTTAAGAAAACAATCAACAATGGCAAAAGATGAGCCAGATGATGATACACTT
CCTGACAAAGACGCAGCGAAAGGTTTCTACGCAAAATATGAACCAAAAGAGGTTCTTGGA
CGTGGCATTTCATCGGTCGTACGTCGATGTATTGATAAGGAAACTGGTAAAGAGTATGCG
GCAAAGATTATTGATTTGGGAGCATCGGACGTAAATGATTCACATCAGATGCTCGAAGCG
ACTCGTCAAGAAATTAATATTTTGAGGCAAGTTATGGGTCATCCTTATATAATTGAATTG
CAAGATGTATTCGAATCTGATGCCTTTATTTTCCTTGTTTTTGAGCTATGTCGTCATGGT
GAATTGTTTGATTATCTTACATCTGTAGTTACATTATCTGAGAAAAAGACACGTTATATT
ATGAGACAAATTTTTGAAGGTGTTGATTATATTCATTCACGCAATATCGTCCATCGTGAC
CTGAAACCCGAAAATATACTCCTCGATGACAATCTTAATGTCAAAATCACAGACTTTGGG
TTTGCTCGTCACTTAACCGATGGCATGAAACTTTATGGTACGTTATTATGATAATATATT
GAAAAATGGTTTAATTAAAAATTTGTTTAACTTTAAAGACTTATGTGGGCATGTGGTGTT
ATTATGTTCACACTTCTTGTCGGTTGCCCTCCATTCTGGCATCGAAAGCAGATGATAATG
CTGCGAAATATCATGGAAGGAAAGTACAGTTTTATGTCACCCGAGTGGTCAGATATTTCA
GAGGATCCAAAAGATCTGATAAGAAAATGTCTTGTGGTTGATCCCGAGAAGCGTATAACT
GTTCGCGAAGCTTTGAAGCATCCATTCTTTAACACTGTAATGCGTCGTCAAAGTCAATTT
AATGCTAGGAAGAAATTTCAATTTGCTATACTATGCGTACGAGCTATGATAAGAATACAA
AGATTGCGCTACACACCTGAACCGCTCGACATCGAAGAAGCCTTACGCGATCCATATCGT
GTCAAAGTATTGCGTAAAGTCATCGATGCATGTGCTTTCCGCGTTTACGGCCATTGGGTC
AAGAAAGGCGAGGGACAGAATCGTGCTGCTCTCTTTGAAAACCAACCAAAAGTTGAACTT
CATAACCTTTACATTCATCAGTTGCAAAAATAA
>g1841.t22 Gene=g1841 Length=187
MAKDEPDDDTLPDKDAAKGFYAKYEPKEVLGRGISSVVRRCIDKETGKEYAAKIIDLGAS
DVNDSHQMLEATRQEINILRQVMGHPYIIELQDVFESDAFIFLVFELCRHGELFDYLTSV
VTLSEKKTRYIMRQIFEGVDYIHSRNIVHRDLKPENILLDDNLNVKITDFGFARHLTDGM
KLYGTLL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g1841.t22 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 6 | 107 | 7.8E-35 |
| 9 | g1841.t22 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 108 | 186 | 1.1E-28 |
| 2 | g1841.t22 | PANTHER | PTHR44167 | OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED | 1 | 183 | 7.9E-97 |
| 3 | g1841.t22 | PANTHER | PTHR44167:SF7 | PHOSPHORYLASE KINASE CATALYTIC SUBUNIT GAMMA 1 | 1 | 183 | 7.9E-97 |
| 1 | g1841.t22 | Pfam | PF00069 | Protein kinase domain | 24 | 180 | 1.1E-47 |
| 7 | g1841.t22 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 30 | 53 | - |
| 6 | g1841.t22 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 147 | 159 | - |
| 10 | g1841.t22 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 24 | 187 | 34.803 |
| 5 | g1841.t22 | SMART | SM00220 | serkin_6 | 24 | 187 | 6.0E-26 |
| 4 | g1841.t22 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 20 | 182 | 1.62E-54 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed