General information for g1841.t34
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform.
Parent gene
- The parent gene g1841 is located on chr_3: 13260701..13261369 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1841 | g1841.t34 | TTS | g1841.t34 | 13254002 | 13254002 |
| chr_3 | g1841 | g1841.t34 | isoform | g1841.t34 | 13254268 | 13261312 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon1 | 13254268 | 13254402 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS1 | 13254268 | 13254402 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon2 | 13254475 | 13254633 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS2 | 13254475 | 13254633 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon3 | 13257131 | 13257304 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS3 | 13257131 | 13257304 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon4 | 13258760 | 13258857 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS4 | 13258760 | 13258857 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon5 | 13258945 | 13259081 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS5 | 13258945 | 13259081 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon6 | 13259167 | 13259257 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS6 | 13259167 | 13259257 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon7 | 13259319 | 13259406 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS7 | 13259319 | 13259406 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon8 | 13259461 | 13259657 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS8 | 13259461 | 13259657 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon9 | 13259736 | 13259905 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS9 | 13259736 | 13259905 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon10 | 13260714 | 13260886 |
| chr_3 | g1841 | g1841.t34 | cds | g1841.t34.CDS10 | 13260714 | 13260742 |
| chr_3 | g1841 | g1841.t34 | exon | g1841.t34.exon11 | 13261177 | 13261312 |
| chr_3 | g1841 | g1841.t34 | TSS | g1841.t34 | 13261336 | 13261336 |
Sequences
>g1841.t34 Gene=g1841 Length=1558
GTTAGATCATAAGTATTGCTTGAGTAGTTAGAATATAAAGACAATTAAATGAAAATAGTG
GAGAATTGTTGAAAAAGTAGCATATAAGAGTGAAAGTTTATTTTTTCATTTTGTACAATT
TTCTCTCGTCGGCCAAGTAAAAAGGAAGATCTTTTGGGATAGTTTGTAATCATTTGAGTA
GCCATTAAGTCTTTAAGAAAACAATCAACAATGGCAAAAGATGAGCCAGATGATGATACA
CTTCCTGACAAAGACGCAGCGAAAGGTTTCTACGCAAAATATGAACCAAAAGAGGTTCTT
GGACGGTGATGGCATTTCATCGGTCGTACGTCGATGTATTGATAAGGAAACTGGTAAAGA
GTATGCGGCAAAGATTATTGATTTGGGAGCATCGGACGTAAATGATTCACATCAGATGCT
CGAAGCGACTCGTCAAGAAATTAATATTTTGAGGCAAGTTATGGGTCATCCTTATATAAT
TGAATTGCAAGATGTATTCGAATCTGATGCCTTTATTTTCCTTGTTTTTGAGCTATGTCG
TCATGGTGAATTGTTTGATTATCTTACATCTGTAGTTACATTATCTGAGAAAAAGACACG
TTATATTATGAGACAAATTTTTGAAGGTGTTGATTATATTCATTCACGCAATATCGTCCA
TCGTGACCTGAAACCCGAAAATATACTCCTCGATGACAATCTTAATGTCAAAATCACAGA
CTTTGGGTTTGCTCGTCACTTAACCGATGGCATGAAACTTTATGACTTATGTGGCACACC
TGGGTATCTTGCACCCGAAACTCTTAAATGTAACATGTTCGAAGACGCACCAGGCTATTC
AAAAGAAGTCGATATGTGGGCATGTGGTGTTATTATGTTCACACTTCTTGTCGGTTGCCC
TCCATTCTGGCATCGAAAGCAGATGATAATGCTGCGAAATATCATGGAAGGAAAGTACAG
TTTTATGTCACCCGAGTGGTCAGATATTTCAGAGGATCCAAAAGATCTGATAAGAAAATG
TCTTGTGGTTGATCCCGAGAAGCGTATAACTGTTCGCGAAGCTTTGAAGCATCCATTCTT
TAACACTGTAAATAAGAATAAGGAGATAGCAAGTAAGGCAACAACGACAACGTCTGATAA
TGAACAGACTAGTATTAATTTAAGTAATGAGACTGAGAGTATTAAAAAACAGGAACCGAA
GAAACAAGTCAATATTGTTATATCATATATTGAACAGAATGACGAGCAAGGAATTGGAAA
ATCGATGCGTCGTCAAAGTCAATTTAATGCTAGGAAGAAATTTCAATTTGCTATACTATG
CGTACGAGCTATGATAAGAATACAAAGATTGCGCTACACACCTGAACCGCTCGACATCGA
AGAAGCCTTACGCGATCCATATCGTGTCAAAGTATTGCGTAAAGTCATCGATGCATGTGC
TTTCCGCGTTTACGGCCATTGGGTCAAGAAAGGCGAGGGACAGAATCGTGCTGCTCTCTT
TGAAAACCAACCAAAAGTTGAACTTCATAACCTTTACATTCATCAGTTGCAAAAATAA
>g1841.t34 Gene=g1841 Length=425
MNQKRFLDGDGISSVVRRCIDKETGKEYAAKIIDLGASDVNDSHQMLEATRQEINILRQV
MGHPYIIELQDVFESDAFIFLVFELCRHGELFDYLTSVVTLSEKKTRYIMRQIFEGVDYI
HSRNIVHRDLKPENILLDDNLNVKITDFGFARHLTDGMKLYDLCGTPGYLAPETLKCNMF
EDAPGYSKEVDMWACGVIMFTLLVGCPPFWHRKQMIMLRNIMEGKYSFMSPEWSDISEDP
KDLIRKCLVVDPEKRITVREALKHPFFNTVNKNKEIASKATTTTSDNEQTSINLSNETES
IKKQEPKKQVNIVISYIEQNDEQGIGKSMRRQSQFNARKKFQFAILCVRAMIRIQRLRYT
PEPLDIEEALRDPYRVKVLRKVIDACAFRVYGHWVKKGEGQNRAALFENQPKVELHNLYI
HQLQK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g1841.t34 | CDD | cd14093 | STKc_PhKG | 9 | 267 | 0.0 |
| 12 | g1841.t34 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 8 | 90 | 1.0E-25 |
| 13 | g1841.t34 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 91 | 277 | 3.5E-75 |
| 20 | g1841.t34 | MobiDBLite | mobidb-lite | consensus disorder prediction | 278 | 299 | - |
| 21 | g1841.t34 | MobiDBLite | mobidb-lite | consensus disorder prediction | 278 | 303 | - |
| 2 | g1841.t34 | PANTHER | PTHR44167 | OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED | 9 | 422 | 2.0E-205 |
| 3 | g1841.t34 | PANTHER | PTHR44167:SF7 | PHOSPHORYLASE KINASE CATALYTIC SUBUNIT GAMMA 1 | 9 | 422 | 2.0E-205 |
| 10 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 96 | 117 | 9.9E-38 |
| 4 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 259 | 270 | 9.9E-38 |
| 8 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 333 | 348 | 9.9E-38 |
| 6 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 349 | 367 | 9.9E-38 |
| 5 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 368 | 382 | 9.9E-38 |
| 9 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 383 | 398 | 9.9E-38 |
| 7 | g1841.t34 | PRINTS | PR01049 | Phosphorylase kinase family signature | 399 | 412 | 9.9E-38 |
| 1 | g1841.t34 | Pfam | PF00069 | Protein kinase domain | 9 | 267 | 3.3E-77 |
| 15 | g1841.t34 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 189 | - |
| 16 | g1841.t34 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 190 | 210 | - |
| 14 | g1841.t34 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 211 | 425 | - |
| 19 | g1841.t34 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 125 | 137 | - |
| 22 | g1841.t34 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 2 | 267 | 51.156 |
| 18 | g1841.t34 | SMART | SM00220 | serkin_6 | 1 | 267 | 2.2E-105 |
| 11 | g1841.t34 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 9 | 295 | 4.99E-88 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005978 | glycogen biosynthetic process | BP |
| GO:0005524 | ATP binding | MF |
| GO:0004689 | phosphorylase kinase activity | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
| GO:0005516 | calmodulin binding | MF |
| GO:0005964 | phosphorylase kinase complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02831 (ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
