General information for g1841.t44
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform.
Parent gene
- The parent gene g1841 is located on chr_3: 13260701..13261369 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1841 | g1841.t44 | isoform | g1841.t44 | 13259173 | 13261300 |
| chr_3 | g1841 | g1841.t44 | exon | g1841.t44.exon1 | 13259173 | 13259257 |
| chr_3 | g1841 | g1841.t44 | cds | g1841.t44.CDS1 | 13259175 | 13259257 |
| chr_3 | g1841 | g1841.t44 | exon | g1841.t44.exon2 | 13259319 | 13259406 |
| chr_3 | g1841 | g1841.t44 | cds | g1841.t44.CDS2 | 13259319 | 13259406 |
| chr_3 | g1841 | g1841.t44 | exon | g1841.t44.exon3 | 13259461 | 13259657 |
| chr_3 | g1841 | g1841.t44 | cds | g1841.t44.CDS3 | 13259461 | 13259657 |
| chr_3 | g1841 | g1841.t44 | exon | g1841.t44.exon4 | 13259736 | 13259905 |
| chr_3 | g1841 | g1841.t44 | cds | g1841.t44.CDS4 | 13259736 | 13259905 |
| chr_3 | g1841 | g1841.t44 | exon | g1841.t44.exon5 | 13260718 | 13260886 |
| chr_3 | g1841 | g1841.t44 | cds | g1841.t44.CDS5 | 13260718 | 13260812 |
| chr_3 | g1841 | g1841.t44 | exon | g1841.t44.exon6 | 13261177 | 13261300 |
| chr_3 | g1841 | g1841.t44 | TSS | g1841.t44 | 13261336 | 13261336 |
| chr_3 | g1841 | g1841.t44 | TTS | g1841.t44 | NA | NA |
Sequences
>g1841.t44 Gene=g1841 Length=833
GTATTGCTTGAGTAGTTAGAATATAAAGACAATTAAATGAAAATAGTGGAGAATTGTTGA
AAAAGTAGCATATAAGAGTGAAAGTTTATTTTTTCATTTTGTACAATTTTCTCTCGTCGG
CCAAGTAAAAAGGAAGATCTTTTGGGATAGTTTGTAATCATTTGAGTAGCCATTAAGTCT
TTAAGAAAACAATCAACAATGGCAAAAGATGAGCCAGATGATGATACACTTCCTGACAAA
GACGCAGCGAAAGGTTTCTACGCAAAATATGAACCAAAAGAGGTTCTTGGACGTGGCATT
TCATCGGTCGTACGTCGATGTATTGATAAGGAAACTGGTAAAGAGTATGCGGCAAAGATT
ATTGATTTGGGAGCATCGGACGTAAATGATTCACATCAGATGCTCGAAGCGACTCGTCAA
GAAATTAATATTTTGAGGCAAGTTATGGGTCATCCTTATATAATTGAATTGCAAGATGTA
TTCGAATCTGATGCCTTTATTTTCCTTGTTTTTGAGCTATGTCGTCATGGTGAATTGTTT
GATTATCTTACATCTGTAGTTACATTATCTGAGAAAAAGACACGTTATATTATGAGACAA
ATTTTTGAAGGTGTTGATTATATTCATTCACGCAATATCGTCCATCGTGACCTGAAACCC
GAAAATATACTCCTCGATGACAATCTTAATGTCAAAATCACAGACTTTGGGTTTGCTCGT
CACTTAACCGATGGCATGAAACTTTATGACTTATGTGGCACACCTGGGTATCTTGCACCC
GAAACTCTTAAATGTAACATGTTCGAAGACGCACCAGGCTATTCAAAAGAAGT
>g1841.t44 Gene=g1841 Length=211
MAKDEPDDDTLPDKDAAKGFYAKYEPKEVLGRGISSVVRRCIDKETGKEYAAKIIDLGAS
DVNDSHQMLEATRQEINILRQVMGHPYIIELQDVFESDAFIFLVFELCRHGELFDYLTSV
VTLSEKKTRYIMRQIFEGVDYIHSRNIVHRDLKPENILLDDNLNVKITDFGFARHLTDGM
KLYDLCGTPGYLAPETLKCNMFEDAPGYSKE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g1841.t44 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 6 | 107 | 1.1E-34 |
| 9 | g1841.t44 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 108 | 211 | 4.9E-39 |
| 2 | g1841.t44 | PANTHER | PTHR44167 | OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED | 1 | 211 | 6.4E-116 |
| 3 | g1841.t44 | PANTHER | PTHR44167:SF7 | PHOSPHORYLASE KINASE CATALYTIC SUBUNIT GAMMA 1 | 1 | 211 | 6.4E-116 |
| 1 | g1841.t44 | Pfam | PF00069 | Protein kinase domain | 24 | 202 | 2.6E-55 |
| 7 | g1841.t44 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 30 | 53 | - |
| 6 | g1841.t44 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 147 | 159 | - |
| 10 | g1841.t44 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 24 | 211 | 39.891 |
| 5 | g1841.t44 | SMART | SM00220 | serkin_6 | 24 | 211 | 1.0E-43 |
| 4 | g1841.t44 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 20 | 200 | 1.75E-62 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
