General information for g1897.t40
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Hexokinase type 2.
Parent gene
- The parent gene g1897 is located on chr_3: 13737692..13738302 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1897 | g1897.t40 | TTS | g1897.t40 | 13736384 | 13736384 |
| chr_3 | g1897 | g1897.t40 | isoform | g1897.t40 | 13736582 | 13738302 |
| chr_3 | g1897 | g1897.t40 | exon | g1897.t40.exon1 | 13736582 | 13736729 |
| chr_3 | g1897 | g1897.t40 | cds | g1897.t40.CDS1 | 13736582 | 13736729 |
| chr_3 | g1897 | g1897.t40 | exon | g1897.t40.exon2 | 13736957 | 13737618 |
| chr_3 | g1897 | g1897.t40 | cds | g1897.t40.CDS2 | 13736957 | 13737567 |
| chr_3 | g1897 | g1897.t40 | exon | g1897.t40.exon3 | 13737685 | 13737787 |
| chr_3 | g1897 | g1897.t40 | exon | g1897.t40.exon4 | 13737849 | 13738302 |
| chr_3 | g1897 | g1897.t40 | TSS | g1897.t40 | 13738426 | 13738426 |
Sequences
>g1897.t40 Gene=g1897 Length=1367
ATGACAAACTCTATTCCACAAAAAGTGCATGACGCGATCGATAGAGATTTAGTACTAGAT
AACAAGAAATTAAATGATGTAATGGTAAAGTTTGAAAGAGAAATTAAAAAGGGTCTTTCA
AAGGCGCATCATGATGAATCGGAAGTAAAATGTTTTGTGACATATGTTCAAAATTTACCA
ATGGGAACTGAAAAGGGCAAATTTTTAGCTCTTGATTTGGGTGGCACGAATTTTCGTGTG
CTTCTTATTATTCTCAAGGGAGAAGAAGATTATGAATTTAAATCAAAAATTTTTGCTATC
CCTCAATCTTTAATGGTCGGCTCTGGTCGTGATTTATTTGATCATATTGCGCAATGTTTG
GCAGAATTCATAAAAGATATGAACATTCAAAATGAGATTTTGCCTCTCGGATTCACTTTT
AGTTTTCCCTGTCAACAAAAAGGACTAACCACTGGCACCCTCATTAAATGGACCAAAGGG
TTTAATTGTAGTGACGTTGTTGAGAAAAATGTAGTTGAGTTATTAGAAGAGGCAATTCAA
CGTCGTAATGTGAGTTTGATATTAAAATTTTAATTTGTGCTATACTTAATGATACAACCG
GAACTCTCATGTCTTGTGCATGGAAATATCAAGACTGTAAAATTGGAGTTATAATTGGAA
CCGGCTCTAATGCCTGTTATGTAGAGAAGGTCAGATACGCAGAGTGGTTTGATAAACCCG
GAAAATTTGACGATGAAAGCGTGATCATCAATACAGAGTTTGGTGCATTCGGAGACAAAG
GCAGTTTGGATGATATTCGAACATGTTTTGATATTGAAGTTGATAAAAATAGCATAAACC
CGAGTAATCAATTGTTTGAGAAAATGATTTCGGGAATGTATATGGGTGAACTTGTTAGAT
TGGTCATTGTGAAATTAGCCTCAAAAGGTTTAATTTTCAATGGCAAAATTTCTAAGAAAT
TTATGCAACGAGAAACATTTTTTACAAAATATATTTCTGAAATTGAGCATGAAGAAAATA
ATGTTTTTCATGCAACAAAAGAAATTTTGTATGAACTGGATATTGAAAATCCAACCGAAG
AAGATTGTCGTATTGTTCGATATTGTTGCGAATTGATAAGCAAGCGAGCAGCACAACTCG
TTTCAAGTGGTTTAGCAGTTCTTATGCTACGTATTGGTGATCCGAAGATCACTATCGGCG
TTGATGGCTCTGTATATAGGTTTCACCCCCGCTTTCATGATCTTATGACCGAAACTATAA
AACAATTGATTCCATCAAATTATGAATTTAAATTGGTACTTTCCGAAGATGGCAGCGGCA
GAGGAGCTGCTTTAGTTGCAGCTGTAGCATCTAAGGATCTTCAATGA
>g1897.t40 Gene=g1897 Length=252
MSCAWKYQDCKIGVIIGTGSNACYVEKVRYAEWFDKPGKFDDESVIINTEFGAFGDKGSL
DDIRTCFDIEVDKNSINPSNQLFEKMISGMYMGELVRLVIVKLASKGLIFNGKISKKFMQ
RETFFTKYISEIEHEENNVFHATKEILYELDIENPTEEDCRIVRYCCELISKRAAQLVSS
GLAVLMLRIGDPKITIGVDGSVYRFHPRFHDLMTETIKQLIPSNYEFKLVLSEDGSGRGA
ALVAAVASKDLQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g1897.t40 | Coils | Coil | Coil | 244 | 252 | - |
| 9 | g1897.t40 | Gene3D | G3DSA:3.40.367.20 | - | 1 | 233 | 3.7E-88 |
| 2 | g1897.t40 | PANTHER | PTHR19443:SF4 | HEXOKINASE-2 | 1 | 249 | 2.7E-82 |
| 3 | g1897.t40 | PANTHER | PTHR19443 | HEXOKINASE | 1 | 249 | 2.7E-82 |
| 5 | g1897.t40 | PRINTS | PR00475 | Hexokinase family signature | 12 | 26 | 6.9E-40 |
| 4 | g1897.t40 | PRINTS | PR00475 | Hexokinase family signature | 81 | 103 | 6.9E-40 |
| 7 | g1897.t40 | PRINTS | PR00475 | Hexokinase family signature | 163 | 185 | 6.9E-40 |
| 6 | g1897.t40 | PRINTS | PR00475 | Hexokinase family signature | 230 | 246 | 6.9E-40 |
| 1 | g1897.t40 | Pfam | PF03727 | Hexokinase | 11 | 246 | 7.3E-81 |
| 11 | g1897.t40 | ProSiteProfiles | PS51748 | Hexokinase domain profile. | 1 | 245 | 27.442 |
| 8 | g1897.t40 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 9 | 249 | 2.29E-80 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0001678 | cellular glucose homeostasis | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0005536 | glucose binding | MF |
| GO:0004396 | hexokinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
