General information for g1897.t45
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Hexokinase type 2.
Parent gene
- The parent gene g1897 is located on chr_3: 13737692..13738302 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1897 | g1897.t45 | isoform | g1897.t45 | 13737692 | 13738302 |
| chr_3 | g1897 | g1897.t45 | exon | g1897.t45.exon1 | 13737692 | 13737787 |
| chr_3 | g1897 | g1897.t45 | cds | g1897.t45.CDS1 | 13737693 | 13737787 |
| chr_3 | g1897 | g1897.t45 | exon | g1897.t45.exon2 | 13737849 | 13738302 |
| chr_3 | g1897 | g1897.t45 | cds | g1897.t45.CDS2 | 13737849 | 13738302 |
| chr_3 | g1897 | g1897.t45 | TSS | g1897.t45 | 13738426 | 13738426 |
| chr_3 | g1897 | g1897.t45 | TTS | g1897.t45 | NA | NA |
Sequences
>g1897.t45 Gene=g1897 Length=550
ATGACAAACTCTATTCCACAAAAAGTGCATGACGCGATCGATAGAGATTTAGTACTAGAT
AACAAGAAATTAAATGATGTAATGGTAAAGTTTGAAAGAGAAATTAAAAAGGGTCTTTCA
AAGGCGCATCATGATGAATCGGAAGTAAAATGTTTTGTGACATATGTTCAAAATTTACCA
ATGGGAACTGAAAAGGGCAAATTTTTAGCTCTTGATTTGGGTGGCACGAATTTTCGTGTG
CTTCTTATTATTCTCAAGGGAGAAGAAGATTATGAATTTAAATCAAAAATTTTTGCTATC
CCTCAATCTTTAATGGTCGGCTCTGGTCGTGATTTATTTGATCATATTGCGCAATGTTTG
GCAGAATTCATAAAAGATATGAACATTCAAAATGAGATTTTGCCTCTCGGATTCACTTTT
AGTTTTCCCTGTCAACAAAAAGGACTAACCACTGGCACCCTCATTAAATGGACCAAAGGG
TTTAATTGTAGTGACGTTGTTGAGAAAAATGTAGTTGAGTTATTAGAAGAGGCAATTCAA
CGTCGTAATG
>g1897.t45 Gene=g1897 Length=183
MTNSIPQKVHDAIDRDLVLDNKKLNDVMVKFEREIKKGLSKAHHDESEVKCFVTYVQNLP
MGTEKGKFLALDLGGTNFRVLLIILKGEEDYEFKSKIFAIPQSLMVGSGRDLFDHIAQCL
AEFIKDMNIQNEILPLGFTFSFPCQQKGLTTGTLIKWTKGFNCSDVVEKNVVELLEEAIQ
RRN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g1897.t45 | CDD | cd00012 | NBD_sugar-kinase_HSP70_actin | 69 | 157 | 7.26796E-6 |
| 8 | g1897.t45 | Gene3D | G3DSA:3.40.367.20 | - | 17 | 53 | 1.3E-64 |
| 7 | g1897.t45 | Gene3D | G3DSA:3.30.420.40 | - | 54 | 182 | 1.3E-64 |
| 2 | g1897.t45 | PANTHER | PTHR19443:SF4 | HEXOKINASE-2 | 15 | 182 | 1.5E-67 |
| 3 | g1897.t45 | PANTHER | PTHR19443 | HEXOKINASE | 15 | 182 | 1.5E-67 |
| 4 | g1897.t45 | PRINTS | PR00475 | Hexokinase family signature | 69 | 85 | 1.1E-19 |
| 5 | g1897.t45 | PRINTS | PR00475 | Hexokinase family signature | 136 | 161 | 1.1E-19 |
| 1 | g1897.t45 | Pfam | PF00349 | Hexokinase | 12 | 182 | 7.6E-59 |
| 10 | g1897.t45 | ProSitePatterns | PS00378 | Hexokinase domain signature. | 136 | 161 | - |
| 11 | g1897.t45 | ProSiteProfiles | PS51748 | Hexokinase domain profile. | 4 | 183 | 20.48 |
| 6 | g1897.t45 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 8 | 183 | 1.91E-61 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0001678 | cellular glucose homeostasis | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0006096 | glycolytic process | BP |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0005536 | glucose binding | MF |
| GO:0004396 | hexokinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
