General information for g1983.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 9e2.
Parent gene
- The parent gene g1983 is located on chr_3: 14187931..14189771 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1983 | g1983.t1 | TTS | g1983.t1 | 14187786 | 14187786 |
| chr_3 | g1983 | g1983.t1 | isoform | g1983.t1 | 14187931 | 14189771 |
| chr_3 | g1983 | g1983.t1 | exon | g1983.t1.exon1 | 14187931 | 14188108 |
| chr_3 | g1983 | g1983.t1 | cds | g1983.t1.CDS1 | 14187931 | 14188108 |
| chr_3 | g1983 | g1983.t1 | exon | g1983.t1.exon2 | 14188176 | 14188599 |
| chr_3 | g1983 | g1983.t1 | cds | g1983.t1.CDS2 | 14188176 | 14188599 |
| chr_3 | g1983 | g1983.t1 | exon | g1983.t1.exon3 | 14188680 | 14189270 |
| chr_3 | g1983 | g1983.t1 | cds | g1983.t1.CDS3 | 14188680 | 14189270 |
| chr_3 | g1983 | g1983.t1 | exon | g1983.t1.exon4 | 14189325 | 14189512 |
| chr_3 | g1983 | g1983.t1 | cds | g1983.t1.CDS4 | 14189325 | 14189512 |
| chr_3 | g1983 | g1983.t1 | exon | g1983.t1.exon5 | 14189572 | 14189771 |
| chr_3 | g1983 | g1983.t1 | cds | g1983.t1.CDS5 | 14189572 | 14189771 |
| chr_3 | g1983 | g1983.t1 | TSS | g1983.t1 | 14189831 | 14189831 |
Sequences
>g1983.t1 Gene=g1983 Length=1581
ATGTTGATAATAATTTTATGTATCACTACAGTTTATCTAATATATAAATGGTCAATTTCA
ACATTTGATTACTTTGAAAAGCAAGGAATTCCTTATAATAAACCATTGCCGCTCGTTGGT
TCAAATATAAATACATTTTTTGATAGAAAACCTTTTATTGATGTTCTTCATAAATGGTAT
AATGAGTTCAAAAATGAAAGACTCTCAGGTTTGTTTGAATTTCGAAGACCAGCAGTTTTG
GTTAAAGACCCAAAACTTATAAAGCAATTAGCTGTCAAAGATTTCGAACATTTTATGGAT
CATCGATCAGTCATTGATGAAGATGTTGATCCACTTTTTGGTAAAAACCTTATTGCTTTA
AAAGGAAATAAGTGGCGAGAGATTAGAGCGACTCTTTCACCTGCTTTCACTGGTAGTAAA
ATGAGAAATATGATGGATTTTGTCAGCACAGTTGGACATCAAACAGCTGAAGCAATTAAA
AAAGATATAAAATCTGGTGGTGTCAATACATTTGAATTTGAAGAATTTGCATCGAAATTT
ACAATTGATATCATAGCTTCGACAGCTTTTGGGATAGAGATAAATTCATTTAAAAATCCT
ACAAATGAATTTTTCAAAGTTGCAAAAGAAATTACAAATTTTGCTACATTAAAAATTGGC
CTCAAATTTGCTGGGTATCTTTTATTTCCAAAATTAATGAAAATGCTGAATGTTCATCTT
CTTGATAAAGTAGGTTGTGATTATTTTGAAAACGTCATTTGTGATACAATTCAAACACGT
GAAAAGAAAGGCATTATGAGAAATGACATGATTCAGTTACTATTGCAAGCGAAGGCAGGA
AAATTATCAATTGAAACAGAAGGAAAAAACACTGAAGGTTTCGCAACTACTGCGGAATCT
CAGTTAGGAAAAAATGAAGTGAAAATAAAATGGGATGAAATTGACTTGGTGGCTCAATGC
TTTTCATTTTTTGTTGCTGGTTTTTCTACAGTTGCACAAACAATGAGCTTTGTTGGTTAT
GAGTTGGCATGCAATCCAGATGTGCAACAAAAACTTTTTAAAGAAATTTCTGAAATGAAT
AATGAAATCAATGGAGAAAAGATCAGTTATGAACAAATTCAAAAAATGAAATATCTTGAT
GCAGTCATCTCTGAAACTTTGAGAAAATGGCCTGCTGCACCTGTAACAGATCGAATTTGT
GTAAAAGACTATGAACTTAAATATGACAATAAATGCATTAAATTCGAAGCAAATAAAACA
ATCATGTTGATACCAATATGGAGCATTCATAGAGACCCAAAATATTATCAAAATCCTGAT
AAATTCGATCCGGAAAGATTCAATGATGAAAACAAAAAATTAATCGATCCTGACACTTAT
TTGCCGTTTGGTGTTGGTCCTAGAAATTGCATTGGCAGTCGATTCGCATTAATGGAAATC
AAAACATTTTTCTACTATTTGCTCTTAAATTTTACCATCGAAGTCACAGAAAAGACTCAA
ATTCCATTAACTTTTGAAAATTCAGCATTTGCTATCAAACCAAAGAAAGGAATTTGGGTT
GAATTGAAACCACGATCGTAA
>g1983.t1 Gene=g1983 Length=526
MLIIILCITTVYLIYKWSISTFDYFEKQGIPYNKPLPLVGSNINTFFDRKPFIDVLHKWY
NEFKNERLSGLFEFRRPAVLVKDPKLIKQLAVKDFEHFMDHRSVIDEDVDPLFGKNLIAL
KGNKWREIRATLSPAFTGSKMRNMMDFVSTVGHQTAEAIKKDIKSGGVNTFEFEEFASKF
TIDIIASTAFGIEINSFKNPTNEFFKVAKEITNFATLKIGLKFAGYLLFPKLMKMLNVHL
LDKVGCDYFENVICDTIQTREKKGIMRNDMIQLLLQAKAGKLSIETEGKNTEGFATTAES
QLGKNEVKIKWDEIDLVAQCFSFFVAGFSTVAQTMSFVGYELACNPDVQQKLFKEISEMN
NEINGEKISYEQIQKMKYLDAVISETLRKWPAAPVTDRICVKDYELKYDNKCIKFEANKT
IMLIPIWSIHRDPKYYQNPDKFDPERFNDENKKLIDPDTYLPFGVGPRNCIGSRFALMEI
KTFFYYLLLNFTIEVTEKTQIPLTFENSAFAIKPKKGIWVELKPRS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g1983.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 13 | 526 | 1.0E-132 |
| 2 | g1983.t1 | PANTHER | PTHR24292 | CYTOCHROME P450 | 2 | 516 | 1.3E-192 |
| 3 | g1983.t1 | PANTHER | PTHR24292:SF90 | CYTOCHROME P450 317A1-RELATED | 2 | 516 | 1.3E-192 |
| 7 | g1983.t1 | PRINTS | PR00463 | E-class P450 group I signature | 315 | 332 | 5.6E-21 |
| 9 | g1983.t1 | PRINTS | PR00385 | P450 superfamily signature | 326 | 343 | 2.5E-11 |
| 8 | g1983.t1 | PRINTS | PR00463 | E-class P450 group I signature | 335 | 361 | 5.6E-21 |
| 10 | g1983.t1 | PRINTS | PR00385 | P450 superfamily signature | 381 | 392 | 2.5E-11 |
| 6 | g1983.t1 | PRINTS | PR00463 | E-class P450 group I signature | 425 | 449 | 5.6E-21 |
| 5 | g1983.t1 | PRINTS | PR00463 | E-class P450 group I signature | 460 | 470 | 5.6E-21 |
| 11 | g1983.t1 | PRINTS | PR00385 | P450 superfamily signature | 461 | 470 | 2.5E-11 |
| 4 | g1983.t1 | PRINTS | PR00463 | E-class P450 group I signature | 470 | 493 | 5.6E-21 |
| 12 | g1983.t1 | PRINTS | PR00385 | P450 superfamily signature | 470 | 481 | 2.5E-11 |
| 1 | g1983.t1 | Pfam | PF00067 | Cytochrome P450 | 32 | 518 | 1.0E-86 |
| 17 | g1983.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 18 | g1983.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 1 | - |
| 19 | g1983.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 2 | 13 | - |
| 20 | g1983.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 21 | - |
| 16 | g1983.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 526 | - |
| 14 | g1983.t1 | ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 463 | 472 | - |
| 13 | g1983.t1 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 30 | 525 | 1.31E-107 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K17861 (cytochrome P450 family 13)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
