General information for g2045.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative rRNA 2’-O-methyltransferase fibrillarin.
Parent gene
- The parent gene g2045 is located on chr_3: 14816687..14820911 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2045 | g2045.t2 | isoform | g2045.t2 | 14816146 | 14817049 |
| chr_3 | g2045 | g2045.t2 | exon | g2045.t2.exon1 | 14816146 | 14817049 |
| chr_3 | g2045 | g2045.t2 | cds | g2045.t2.CDS1 | 14816462 | 14816755 |
| chr_3 | g2045 | g2045.t2 | TSS | g2045.t2 | NA | NA |
| chr_3 | g2045 | g2045.t2 | TTS | g2045.t2 | NA | NA |
Sequences
>g2045.t2 Gene=g2045 Length=904
ACTGATGGTGAGAAAAAAGAATATCGTGTTTGGAATCCATTCAGATCAAAGTTAGCAGCA
GCTATTCTCGGTGGAGTTGAAGAAATCTATATAGCACCAGGTTCAAAGGTTTTATATCTT
GGTGCAGCTTCAGGAACCACTGTTAGTCATGTGAGTGATGTTGTTGGTCCTGAAGGTCTC
GTTTATGCAGTAGAATTCTCTCATCGTTCCGGTCGTGATCTTATAAATGTTGCCAAGAAA
CGAACCAACATTATTCCAATCATTGAAGATGCTCGACATCCACACAAATATCGAATGTTA
GTAGGAATGGTTGATACCATTTTTGCGGATGTTGCTCAACCCGATCAGGCTCGTATTGTG
ATACTTAATGCACAAAACTTTCTCAAAACGGGCGGGCATTTTGTTATTTCCATCAAAGCA
TCTTGTATTGATTCAACAGCCAAACCTGAAGCTGTATTCGCATCAGAAGTTGATAAACTC
AAAGCTGAAAAATTGAAACCTCTAGAACAAGTGACATTAGAACCTTATGAAAGAGATCAC
GCAGTTGTTTGTGGAGTTTTTAGACCACCAGAAAAGAAAAAGAACTAATCAAGATTTAAG
AAAGACTAGTTGTAAGATTTTTTCGTCTCCTAATTTTGAATTTTACTTCTATCATATATT
TTTGGACCAGCAAGATAACAAAAATAAGAAAAAAATTTTTGAATAAAAAAAAGAATCAAT
CCTGCTACATTTATCTAAGAATATAATAAACAATTATAAAGAATTAATATGATGATTTTT
ATTCAAGAATAAAGATTTAAAAAGAATAAAACAATACATGTGTTTTACTTAAATAAAAGT
TTACACATACATTGACAATAAAAATCAGCTGTTGATTCATGTGCAAGTATTTTTTTTGTA
GTTG
>g2045.t2 Gene=g2045 Length=97
MLVGMVDTIFADVAQPDQARIVILNAQNFLKTGGHFVISIKASCIDSTAKPEAVFASEVD
KLKAEKLKPLEQVTLEPYERDHAVVCGVFRPPEKKKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2045.t2 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 1 | 91 | 0 |
| 2 | g2045.t2 | PANTHER | PTHR10335:SF6 | RRNA/TRNA 2’-O-METHYLTRANSFERASE FIBRILLARIN-LIKE PROTEIN 1 | 1 | 95 | 0 |
| 3 | g2045.t2 | PANTHER | PTHR10335 | RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN | 1 | 95 | 0 |
| 4 | g2045.t2 | PRINTS | PR00052 | Fibrillarin signature | 16 | 45 | 0 |
| 5 | g2045.t2 | PRINTS | PR00052 | Fibrillarin signature | 68 | 89 | 0 |
| 1 | g2045.t2 | Pfam | PF01269 | Fibrillarin | 1 | 90 | 0 |
| 7 | g2045.t2 | SMART | SM01206 | Fibrillarin_2 | 1 | 91 | 0 |
| 6 | g2045.t2 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 88 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003723 | RNA binding | MF |
| GO:0008168 | methyltransferase activity | MF |
| GO:0006364 | rRNA processing | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
