General information for g2049.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as histone-arginine N-methyltransferase.
Parent gene
- The parent gene g2049 is located on chr_3: 14829094..14829944 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2049 | g2049.t7 | isoform | g2049.t7 | 14828184 | 14829944 |
| chr_3 | g2049 | g2049.t7 | exon | g2049.t7.exon1 | 14828184 | 14828190 |
| chr_3 | g2049 | g2049.t7 | cds | g2049.t7.CDS1 | 14828184 | 14828190 |
| chr_3 | g2049 | g2049.t7 | exon | g2049.t7.exon2 | 14828257 | 14828346 |
| chr_3 | g2049 | g2049.t7 | cds | g2049.t7.CDS2 | 14828257 | 14828346 |
| chr_3 | g2049 | g2049.t7 | exon | g2049.t7.exon3 | 14828408 | 14828540 |
| chr_3 | g2049 | g2049.t7 | cds | g2049.t7.CDS3 | 14828408 | 14828540 |
| chr_3 | g2049 | g2049.t7 | exon | g2049.t7.exon4 | 14828618 | 14829541 |
| chr_3 | g2049 | g2049.t7 | cds | g2049.t7.CDS4 | 14828618 | 14829398 |
| chr_3 | g2049 | g2049.t7 | exon | g2049.t7.exon5 | 14829799 | 14829944 |
| chr_3 | g2049 | g2049.t7 | TSS | g2049.t7 | 14830113 | 14830113 |
| chr_3 | g2049 | g2049.t7 | TTS | g2049.t7 | NA | NA |
Sequences
>g2049.t7 Gene=g2049 Length=1300
ATGTTGAGAAAGGCTTTGACTCTATCGCTGTGTAAAATTATTAACATCAATACTTTAGAA
GAGCGTACTTTTCAAAAAGAAATTGGCCTAAAATTATGGTGTATTTATGATCCCGAAGGA
GTTGTTTTAAAATTTATCAAAGGCAAAAAATGATAAACATATTAAAAATGGAACCTCAAA
TGAGGAAGAAAGTGAATGTATAGAACTCGAAGTTTTAATTACAAAGAAGACGGTTTTAAA
GAAACAAAAGGATTTACATGTTATTAATACAGCAGATGACATAATATTGATGAAGTTATT
ATCGCAAGATGAAGACAAACAGTTTGATGAGGTTCTTAAAAAAGTGCAAAATGTTAACAA
TTCAGTATTTATTATGAGAACCGAGGACTCCAGTGCGAATCAATATTTTCAATTTTACGG
ATATTTGAGTCAGCAACAAAATATGATGCAAGACTTTGTACGCACGAGCACTTATCAGAA
AGCAATACATAGCAATTCATTTGACTTTGTAGACAGAATAGTGCTCGATGTTGGCGCTGG
TAGCGGCATTCTTTCATTTTTTGCTGCTCAAGCTGGTGCAAAAAAAGTTTATGCAGTTGA
GGCAAGCAATATGGCTCAATATGCTCAGCAATTGGTGGCAGCTAATAACTTAAGTGATCG
AATAACTGTTATTGCGGGAAAAATTGAAGAAATAGACTTGCCAGAAAAGGTGGATGTAAT
TATTAGTGAACCTATGGGTTATATGCTTTACAATGAACGAATGTTAGAGACATATTTGCA
TGCAAAAAAATGGCTCAAGCCAAACGGTAAAATGTTTCCTTCACGAGGAGATTTACATGT
TGCTCCTTTCTGTGACGAGGCGCTCTACATCGAGCAATACAATAAGGCAAATTTCTGGTA
TCAAAGTTGCTTCCATAATGTCGATTTGAGCTCTCTAAGAGAAGCAGCGATGAAGGAATA
TTTCAGGCAACCTATCGTTGATACTTTTGACATTCGTATTTGTCAGGCAAAGTCTATTCG
ACATGTTGTCGACTTTTTAGAGGCAGCAGAAGAGGACTTGCATAGAATTGAAATTCCACT
CGAATTTCATATGCTGGAAACAAGTACATGTCATGGATTAGCTTTTTGGTTCGATGTTGA
ATTTTGCGGTAGCTCACAGAGTGTTTGGCTATCAACATCACCTACTGAACCACTTACTCA
CTGGTATCAAGTTCGATGTTTACTTCAAAATCCTATATTCGTAAAACAAGGACAATTGTT
AACAGGACGAGTTCTTCTTGTAGCAAATAAAAGACAAAGC
>g2049.t7 Gene=g2049 Length=337
MKLLSQDEDKQFDEVLKKVQNVNNSVFIMRTEDSSANQYFQFYGYLSQQQNMMQDFVRTS
TYQKAIHSNSFDFVDRIVLDVGAGSGILSFFAAQAGAKKVYAVEASNMAQYAQQLVAANN
LSDRITVIAGKIEEIDLPEKVDVIISEPMGYMLYNERMLETYLHAKKWLKPNGKMFPSRG
DLHVAPFCDEALYIEQYNKANFWYQSCFHNVDLSSLREAAMKEYFRQPIVDTFDIRICQA
KSIRHVVDFLEAAEEDLHRIEIPLEFHMLETSTCHGLAFWFDVEFCGSSQSVWLSTSPTE
PLTHWYQVRCLLQNPIFVKQGQLLTGRVLLVANKRQS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2049.t7 | CDD | cd02440 | AdoMet_MTases | 78 | 179 | 0.000 |
| 6 | g2049.t7 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 17 | 177 | 0.000 |
| 5 | g2049.t7 | Gene3D | G3DSA:2.70.160.11 | - | 180 | 337 | 0.000 |
| 2 | g2049.t7 | PANTHER | PTHR11006 | PROTEIN ARGININE N-METHYLTRANSFERASE | 12 | 337 | 0.000 |
| 3 | g2049.t7 | PANTHER | PTHR11006:SF51 | HISTONE-ARGININE METHYLTRANSFERASE CARM1 | 12 | 337 | 0.000 |
| 1 | g2049.t7 | Pfam | PF13649 | Methyltransferase domain | 78 | 173 | 0.000 |
| 7 | g2049.t7 | ProSiteProfiles | PS51678 | SAM-dependent methyltransferase PRMT-type domain profile. | 36 | 337 | 92.952 |
| 4 | g2049.t7 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 42 | 335 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016274 | protein-arginine N-methyltransferase activity | MF |
| GO:0018216 | peptidyl-arginine methylation | BP |
KEGG
Orthology
- This transcript has been annotated with K05931 (type I protein arginine methyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed