General information for g2049.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as histone-arginine N-methyltransferase.
Parent gene
- The parent gene g2049 is located on chr_3: 14829094..14829944 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2049 | g2049.t8 | isoform | g2049.t8 | 14828622 | 14829544 |
| chr_3 | g2049 | g2049.t8 | exon | g2049.t8.exon1 | 14828622 | 14829544 |
| chr_3 | g2049 | g2049.t8 | cds | g2049.t8.CDS1 | 14828622 | 14829398 |
| chr_3 | g2049 | g2049.t8 | TSS | g2049.t8 | 14830113 | 14830113 |
| chr_3 | g2049 | g2049.t8 | TTS | g2049.t8 | NA | NA |
Sequences
>g2049.t8 Gene=g2049 Length=923
CAGAAAATGATAAACATATTAAAAATGGAACCTCAAATGAGGAAGAAAGTGAATGTATAG
AACTCGAAGTTTTAATTACAAAGAAGACGGTTTTAAAGAAACAAAAGGATTTACATGTTA
TTAATACAGCAGATGACATAATATTGATGAAGTTATTATCGCAAGATGAAGACAAACAGT
TTGATGAGGTTCTTAAAAAAGTGCAAAATGTTAACAATTCAGTATTTATTATGAGAACCG
AGGACTCCAGTGCGAATCAATATTTTCAATTTTACGGATATTTGAGTCAGCAACAAAATA
TGATGCAAGACTTTGTACGCACGAGCACTTATCAGAAAGCAATACATAGCAATTCATTTG
ACTTTGTAGACAGAATAGTGCTCGATGTTGGCGCTGGTAGCGGCATTCTTTCATTTTTTG
CTGCTCAAGCTGGTGCAAAAAAAGTTTATGCAGTTGAGGCAAGCAATATGGCTCAATATG
CTCAGCAATTGGTGGCAGCTAATAACTTAAGTGATCGAATAACTGTTATTGCGGGAAAAA
TTGAAGAAATAGACTTGCCAGAAAAGGTGGATGTAATTATTAGTGAACCTATGGGTTATA
TGCTTTACAATGAACGAATGTTAGAGACATATTTGCATGCAAAAAAATGGCTCAAGCCAA
ACGGTAAAATGTTTCCTTCACGAGGAGATTTACATGTTGCTCCTTTCTGTGACGAGGCGC
TCTACATCGAGCAATACAATAAGGCAAATTTCTGGTATCAAAGTTGCTTCCATAATGTCG
ATTTGAGCTCTCTAAGAGAAGCAGCGATGAAGGAATATTTCAGGCAACCTATCGTTGATA
CTTTTGACATTCGTATTTGTCAGGCAAAGTCTATTCGACATGTTGTCGACTTTTTAGAGG
CAGCAGAAGAGGACTTGCATAGA
>g2049.t8 Gene=g2049 Length=259
MKLLSQDEDKQFDEVLKKVQNVNNSVFIMRTEDSSANQYFQFYGYLSQQQNMMQDFVRTS
TYQKAIHSNSFDFVDRIVLDVGAGSGILSFFAAQAGAKKVYAVEASNMAQYAQQLVAANN
LSDRITVIAGKIEEIDLPEKVDVIISEPMGYMLYNERMLETYLHAKKWLKPNGKMFPSRG
DLHVAPFCDEALYIEQYNKANFWYQSCFHNVDLSSLREAAMKEYFRQPIVDTFDIRICQA
KSIRHVVDFLEAAEEDLHR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2049.t8 | CDD | cd02440 | AdoMet_MTases | 78 | 179 | 0.00 |
| 6 | g2049.t8 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 17 | 177 | 0.00 |
| 5 | g2049.t8 | Gene3D | G3DSA:2.70.160.11 | - | 180 | 259 | 0.00 |
| 2 | g2049.t8 | PANTHER | PTHR11006 | PROTEIN ARGININE N-METHYLTRANSFERASE | 12 | 259 | 0.00 |
| 3 | g2049.t8 | PANTHER | PTHR11006:SF51 | HISTONE-ARGININE METHYLTRANSFERASE CARM1 | 12 | 259 | 0.00 |
| 1 | g2049.t8 | Pfam | PF13649 | Methyltransferase domain | 78 | 173 | 0.00 |
| 7 | g2049.t8 | ProSiteProfiles | PS51678 | SAM-dependent methyltransferase PRMT-type domain profile. | 36 | 259 | 68.87 |
| 4 | g2049.t8 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 42 | 234 | 0.00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016274 | protein-arginine N-methyltransferase activity | MF |
| GO:0018216 | peptidyl-arginine methylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
