General information for g2128.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dual specificity mitogen-activated protein kinase kinase dSOR1.
Parent gene
- The parent gene g2128 is located on chr_3: 15354894..15356042 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2128 | g2128.t4 | TSS | g2128.t4 | 15354050 | 15354050 |
| chr_3 | g2128 | g2128.t4 | isoform | g2128.t4 | 15354188 | 15355583 |
| chr_3 | g2128 | g2128.t4 | exon | g2128.t4.exon1 | 15354188 | 15354267 |
| chr_3 | g2128 | g2128.t4 | exon | g2128.t4.exon2 | 15354335 | 15354534 |
| chr_3 | g2128 | g2128.t4 | exon | g2128.t4.exon3 | 15354588 | 15354767 |
| chr_3 | g2128 | g2128.t4 | cds | g2128.t4.CDS1 | 15354762 | 15354767 |
| chr_3 | g2128 | g2128.t4 | exon | g2128.t4.exon4 | 15354826 | 15355416 |
| chr_3 | g2128 | g2128.t4 | cds | g2128.t4.CDS2 | 15354826 | 15355416 |
| chr_3 | g2128 | g2128.t4 | exon | g2128.t4.exon5 | 15355476 | 15355583 |
| chr_3 | g2128 | g2128.t4 | cds | g2128.t4.CDS3 | 15355476 | 15355583 |
| chr_3 | g2128 | g2128.t4 | TTS | g2128.t4 | 15355983 | 15355983 |
Sequences
>g2128.t4 Gene=g2128 Length=1159
ATGTCTAAGAACAAGCTAAATTTGACATTGCCTCCGCCTTCTATCGATGCTTCGATCACT
CCAGCTTTAGCTTCTGCAGAGAAAAAAGAATTACTTGGTACAAAAAATAGTATTGATCAA
TTAACAGAGACTTTAGAAGAACTCGATATGGATGAGAATGCACGCAAAAGGATAAAAGTA
TTTTTAAATCAAAAAGAGAAAATTGGTGAACTCTCAGATCAAGATCTTGAAAAATTAGGA
GAGTTAGGTTCTGGAAATGGAGGTGTAGTGATGATGGCAAGCACGACACAAACCAACTTC
TCTCATAATGGCAAGAAAAATGATTCATCTTGAAGTAAAGCCAGCTATTAAGAAACAAAT
TATTCGTGAATTGAAAGTATTGCATGAATGTAATTTTCCTCATATTGTTGGTTTCTATGG
AGCCTTTTATAGTGATGGCGAAATCAGCATTTGCATGGAGTATATGGACGGTGGTTCACT
TGATTTGATTTTAAAACGTGCTGGACGTATACATGAGAACATTTTGGGCAAAATAACAGT
TGCTGTGTTAAAAGGTTTAACTTATTTACGTGATAAACATGCCATCATTCATAGAGATGT
CAAACCGAGTAATATTTTGGTTAATAGCAGTGGAGAAATAAAAATTTGTGATTTTGGTGT
AAGTGGTCAATTGATTGATTCAATGGCAAACTCATTTGTCGGCACACGTAGCTATATGTC
ACCTGAACGTTTACAAGGAACACATTATTCAGTTCAATCAGACATTTGGTCCTTAGGCCT
CTCATTAGTGGAGATGGCTATAGGAATGTATCCAATTCCACCACCTGACATGCAGACACT
TGATGCTATTCTCGCAAACGATGCACAATCATTAGCAAATCAGACAATTATTGAGCCACG
ATCGATGGCAATTTTTGAATTATTAGACTATATTGTGAATGAGCCACCACCGAAACTAGA
GCATCCTAGTTTCTCGCCCAATTTCAAAGACTTTGTAGATAAATGTTTGAAGAAAAATCC
TGAAGAACGTGCTGATTTAAAGACATTAATGGCTCATGATTGGATAAGACATTCTGAAGA
AGAAAATGTTGATGTAGCTGGTTGGGTTTGTCGAACTATGAATTTGCCTCTTACTCCAAA
ACGCACGATACCACAGTAA
>g2128.t4 Gene=g2128 Length=234
MEYMDGGSLDLILKRAGRIHENILGKITVAVLKGLTYLRDKHAIIHRDVKPSNILVNSSG
EIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP
IPPPDMQTLDAILANDAQSLANQTIIEPRSMAIFELLDYIVNEPPPKLEHPSFSPNFKDF
VDKCLKKNPEERADLKTLMAHDWIRHSEEENVDVAGWVCRTMNLPLTPKRTIPQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g2128.t4 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 6 | 229 | 2.1E-67 |
| 2 | g2128.t4 | PANTHER | PTHR48013:SF19 | DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1 | 1 | 225 | 5.0E-122 |
| 3 | g2128.t4 | PANTHER | PTHR48013 | DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED | 1 | 225 | 5.0E-122 |
| 6 | g2128.t4 | PIRSF | PIRSF000654 | ILK | 1 | 202 | 1.3E-21 |
| 1 | g2128.t4 | Pfam | PF00069 | Protein kinase domain | 1 | 204 | 2.2E-47 |
| 7 | g2128.t4 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 44 | 56 | - |
| 9 | g2128.t4 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 204 | 36.64 |
| 8 | g2128.t4 | SMART | SM00220 | serkin_6 | 1 | 204 | 2.9E-29 |
| 4 | g2128.t4 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 208 | 1.48E-56 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K12132 (eukaryotic-like serine/threonine-protein kinase)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed