Gene loci information

Transcript annotation

  • This transcript has been annotated as Dual specificity mitogen-activated protein kinase kinase dSOR1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2128 g2128.t5 TSS g2128.t5 15354050 15354050
chr_3 g2128 g2128.t5 isoform g2128.t5 15354188 15355583
chr_3 g2128 g2128.t5 exon g2128.t5.exon1 15354188 15354530
chr_3 g2128 g2128.t5 cds g2128.t5.CDS1 15354402 15354530
chr_3 g2128 g2128.t5 exon g2128.t5.exon2 15354588 15354767
chr_3 g2128 g2128.t5 cds g2128.t5.CDS2 15354588 15354767
chr_3 g2128 g2128.t5 exon g2128.t5.exon3 15354826 15355416
chr_3 g2128 g2128.t5 cds g2128.t5.CDS3 15354826 15355416
chr_3 g2128 g2128.t5 exon g2128.t5.exon4 15355476 15355583
chr_3 g2128 g2128.t5 cds g2128.t5.CDS4 15355476 15355583
chr_3 g2128 g2128.t5 TTS g2128.t5 15355983 15355983

Sequences

>g2128.t5 Gene=g2128 Length=1222
ATGTCTAAGAACAAGCTAAATTTGACATTGCCTCCGCCTTCTATCGATGCTTCGATCACT
CCAGCTTTAGCTTCTGCAGAGTAATTAAAATTAGATTAATTCATATTATATATGTATGTA
AATGCTATATGTATGTTCTATTTACAGGAAAAAAGAATTACTTGGTACAAAAAATAGTAT
TGATCAATTAACAGAGACTTTAGAAGAACTCGATATGGATGAGAATGCACGCAAAAGGAT
AAAAGTATTTTTAAATCAAAAAGAGAAAATTGGTGAACTCTCAGATCAAGATCTTGAAAA
ATTAGGAGAGTTAGGTTCTGGAAATGGAGGTGTAGTGATGATGGCACGACACAAACCAAC
TTCTCTCATAATGGCAAGAAAAATGATTCATCTTGAAGTAAAGCCAGCTATTAAGAAACA
AATTATTCGTGAATTGAAAGTATTGCATGAATGTAATTTTCCTCATATTGTTGGTTTCTA
TGGAGCCTTTTATAGTGATGGCGAAATCAGCATTTGCATGGAGTATATGGACGGTGGTTC
ACTTGATTTGATTTTAAAACGTGCTGGACGTATACATGAGAACATTTTGGGCAAAATAAC
AGTTGCTGTGTTAAAAGGTTTAACTTATTTACGTGATAAACATGCCATCATTCATAGAGA
TGTCAAACCGAGTAATATTTTGGTTAATAGCAGTGGAGAAATAAAAATTTGTGATTTTGG
TGTAAGTGGTCAATTGATTGATTCAATGGCAAACTCATTTGTCGGCACACGTAGCTATAT
GTCACCTGAACGTTTACAAGGAACACATTATTCAGTTCAATCAGACATTTGGTCCTTAGG
CCTCTCATTAGTGGAGATGGCTATAGGAATGTATCCAATTCCACCACCTGACATGCAGAC
ACTTGATGCTATTCTCGCAAACGATGCACAATCATTAGCAAATCAGACAATTATTGAGCC
ACGATCGATGGCAATTTTTGAATTATTAGACTATATTGTGAATGAGCCACCACCGAAACT
AGAGCATCCTAGTTTCTCGCCCAATTTCAAAGACTTTGTAGATAAATGTTTGAAGAAAAA
TCCTGAAGAACGTGCTGATTTAAAGACATTAATGGCTCATGATTGGATAAGACATTCTGA
AGAAGAAAATGTTGATGTAGCTGGTTGGGTTTGTCGAACTATGAATTTGCCTCTTACTCC
AAAACGCACGATACCACAGTAA

>g2128.t5 Gene=g2128 Length=335
MDENARKRIKVFLNQKEKIGELSDQDLEKLGELGSGNGGVVMMARHKPTSLIMARKMIHL
EVKPAIKKQIIRELKVLHECNFPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKRAGRI
HENILGKITVAVLKGLTYLRDKHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMAN
SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDMQTLDAILANDAQS
LANQTIIEPRSMAIFELLDYIVNEPPPKLEHPSFSPNFKDFVDKCLKKNPEERADLKTLM
AHDWIRHSEEENVDVAGWVCRTMNLPLTPKRTIPQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g2128.t5 CDD cd06615 PKc_MEK 26 323 0.0
5 g2128.t5 Gene3D G3DSA:3.30.200.20 Phosphorylase Kinase; domain 1 1 106 2.8E-44
6 g2128.t5 Gene3D G3DSA:1.10.510.10 Transferase(Phosphotransferase) domain 1 107 330 7.1E-67
2 g2128.t5 PANTHER PTHR48013:SF19 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1 1 326 1.2E-182
3 g2128.t5 PANTHER PTHR48013 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED 1 326 1.2E-182
7 g2128.t5 PIRSF PIRSF000654 ILK 6 307 2.8E-28
1 g2128.t5 Pfam PF00069 Protein kinase domain 28 305 2.9E-67
10 g2128.t5 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 56 -
9 g2128.t5 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 145 157 -
12 g2128.t5 ProSiteProfiles PS50011 Protein kinase domain profile. 27 305 45.785
11 g2128.t5 SMART SM00220 serkin_6 27 305 4.5E-83
4 g2128.t5 SUPERFAMILY SSF56112 Protein kinase-like (PK-like) 21 309 3.78E-79

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values