General information for g2176.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Eukaryotic translation initiation factor 5.
Parent gene
- The parent gene g2176 is located on chr_3: 15791791..15793413 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2176 | g2176.t7 | isoform | g2176.t7 | 15790409 | 15793163 |
| chr_3 | g2176 | g2176.t7 | exon | g2176.t7.exon1 | 15790409 | 15791269 |
| chr_3 | g2176 | g2176.t7 | cds | g2176.t7.CDS1 | 15790775 | 15791269 |
| chr_3 | g2176 | g2176.t7 | exon | g2176.t7.exon2 | 15791563 | 15792313 |
| chr_3 | g2176 | g2176.t7 | cds | g2176.t7.CDS2 | 15791563 | 15791589 |
| chr_3 | g2176 | g2176.t7 | exon | g2176.t7.exon3 | 15792418 | 15792514 |
| chr_3 | g2176 | g2176.t7 | exon | g2176.t7.exon4 | 15792951 | 15793163 |
| chr_3 | g2176 | g2176.t7 | TSS | g2176.t7 | 15793180 | 15793180 |
| chr_3 | g2176 | g2176.t7 | TTS | g2176.t7 | NA | NA |
Sequences
>g2176.t7 Gene=g2176 Length=1922
TGAGAAAATTTTATTCGTAAAATGTTTTCATCTTATTCTTGTCGTGTGAAAGTTTTATAT
CGTCAAAATAATACCAAACGATAGATAAATAACACCAATATTCTATGTAATTGGAGTTTA
AAAGTCACTTTTTGAGGCAATCGAGAAAAATATAAATCATCAAGTTTTTAAGCTTATCGG
GGGATTTTATGAATTTAAAAAACACATTTGAAGAAAACTTTGATCAGATCGAACAGCCGA
TATTTTTAAATTTATCACATCAGAATCCTTTAAAGTGCATGTCAGCGAATTTAAATCAGT
TGAGTCATAGGACTTCAAAATTTTCAAGCAATCGACATCGGAAATTGCAACCATTTAGAA
AAACATCGTGAATTAGTCATAAACATTGAGTAAAGTGAACAAGAGTTCTATTATTATCAT
CATCATCACCATCATCAAAGAATATAATACATAATCAAAAAAATAAGGGAACGTAATTCA
AATTTAATTTGATAGAAGGATGGGGACTTTGAATGTCAATCGTAATGTTACGGACTTGTA
TTATCGCTACAAGATGCCACGTATTTGTGCCAAAGTAGAAGGCAAGGGCAATGGCATTAA
GACCGTTATTGTCAATATGGCTGAAGTAGCTAAAGCACTCAATCGTCCTGCTACTTATCC
AACTAAATACTTTGGTTGCGAGCTTGGCGCTCAGACTCAATTCGATCATAAGAATGAACG
TTTTATTGTCAATGGCTCGCATGATGCATCAAAATTGCAAGATCTTCTTGATGGATTTAT
TCGCAAATATGTCTTGTGTCCAGAATGCGACAATCCTGAGACCGATTTAATCATTGTTGC
AAAGAAAGAGCAAATTTCGCAAACTTGTAAAGCATGCGGTTTTCATGGATTGCTAAAAGT
TCAGCATAAGGTGAATACTTTTATCTTGAAAAATCCACCAACAATGAATCCAGCTGCACC
AGGTGCATCTTTGACTGAGGGAAAACGTTCTAAGCGCTCCAAGAAAGCTGAAGGTGATTC
AAATCATGCTACAAATGGCGATAGCTCAAAAGATTCCGATGATTCTCGCAGAATTGCTTT
TCACTGAAAATATTACTGCTGAGATAAAGAAACATCGAAATTTGTTGTTGCGCTTCACCC
ATGAAGATGAGAAAGCCCAAAAATATTTATTGGGTGGAGTTGAGCAGGTCATCGCTTTGC
ATGCTGCAAAATTGATTGATAAATCTGCTGTCATTTTGAAATTGTTTTATGACACTGATT
TGATAGATGAAAAGGTTATTTTAGAATGGGGTTCTAAAATCAGCAAAAAATATGTGTCAA
AGGAAGTTGCTCAACAAATTCATGATAAGGCCGCACCATTTGTCAAATGGTTGAAGGAAG
CAGAAGAAGAATCTGAGGACTCTGAAGAGGAAGATGATGATGTTGAAATTGGCTTCGATG
ATCGTGCAAAGGTTGATTCGTTGTCAAGCAATGCTGTTAAACCAGTAGCTCCTGTGAAGA
AACCTATTGTCGATGATGACGAAGATGGAGAAGAGCTAGACATTGATAATATATAAAGAC
ATTGTCTTATATTCATTATGTTTTCTTTGAATATTAATCTACACATATAAAAATAATATA
GCAACCACAATAATGTCAAAGTTTTCTTTTTTTTTGCAAATTGGTTTTTGTAGCTTCACT
ATATTATCAAATTATAATTTTTTCTCAATGCACACAAGTTTTATGATTTTTTGCCAACTT
TTTTTATAGTGTTTTCTTACTTTTATTCCATTTTTAAAAAGTCATATTTGATGAAACATA
AAGATTGATGGAAAAAAGATTTATTGGATATTATCTGGAATTTCAAAAAATGATATGAAA
ACAGAAATCAATTGAAATAAACCTATATTTGGAAGAATACAAAATTTTTTTTCTTATTCT
AT
>g2176.t7 Gene=g2176 Length=173
MAIAQKIPMILAELLFTENITAEIKKHRNLLLRFTHEDEKAQKYLLGGVEQVIALHAAKL
IDKSAVILKLFYDTDLIDEKVILEWGSKISKKYVSKEVAQQIHDKAAPFVKWLKEAEEES
EDSEEEDDDVEIGFDDRAKVDSLSSNAVKPVAPVKKPIVDDDEDGEELDIDNI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g2176.t7 | CDD | cd11561 | W2_eIF5 | 6 | 114 | 4.81864E-45 |
| 6 | g2176.t7 | Coils | Coil | Coil | 113 | 133 | - |
| 5 | g2176.t7 | Gene3D | G3DSA:1.25.40.180 | - | 1 | 139 | 1.6E-46 |
| 9 | g2176.t7 | MobiDBLite | mobidb-lite | consensus disorder prediction | 154 | 173 | - |
| 2 | g2176.t7 | PANTHER | PTHR23001:SF22 | EUKARYOTIC TRANSLATION INITIATION FACTOR 5 | 7 | 145 | 7.7E-42 |
| 3 | g2176.t7 | PANTHER | PTHR23001 | EUKARYOTIC TRANSLATION INITIATION FACTOR | 7 | 145 | 7.7E-42 |
| 1 | g2176.t7 | Pfam | PF02020 | eIF4-gamma/eIF5/eIF2-epsilon | 41 | 123 | 5.0E-21 |
| 10 | g2176.t7 | ProSiteProfiles | PS51363 | W2 domain profile. | 1 | 123 | 26.913 |
| 8 | g2176.t7 | SMART | SM00515 | 542_3 | 29 | 119 | 2.3E-30 |
| 4 | g2176.t7 | SUPERFAMILY | SSF48371 | ARM repeat | 9 | 117 | 2.45E-26 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed