General information for g2225.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Histone acetyltransferase KAT2A.
Parent gene
- The parent gene g2225 is located on chr_3: 16117145..16118544 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2225 | g2225.t3 | isoform | g2225.t3 | 16117145 | 16118544 |
| chr_3 | g2225 | g2225.t3 | exon | g2225.t3.exon1 | 16117145 | 16117228 |
| chr_3 | g2225 | g2225.t3 | cds | g2225.t3.CDS1 | 16117146 | 16117228 |
| chr_3 | g2225 | g2225.t3 | exon | g2225.t3.exon2 | 16117291 | 16117436 |
| chr_3 | g2225 | g2225.t3 | cds | g2225.t3.CDS2 | 16117291 | 16117436 |
| chr_3 | g2225 | g2225.t3 | exon | g2225.t3.exon3 | 16117496 | 16117913 |
| chr_3 | g2225 | g2225.t3 | cds | g2225.t3.CDS3 | 16117496 | 16117913 |
| chr_3 | g2225 | g2225.t3 | exon | g2225.t3.exon4 | 16118147 | 16118327 |
| chr_3 | g2225 | g2225.t3 | cds | g2225.t3.CDS4 | 16118147 | 16118327 |
| chr_3 | g2225 | g2225.t3 | exon | g2225.t3.exon5 | 16118416 | 16118544 |
| chr_3 | g2225 | g2225.t3 | cds | g2225.t3.CDS5 | 16118416 | 16118544 |
| chr_3 | g2225 | g2225.t3 | TSS | g2225.t3 | 16118638 | 16118638 |
| chr_3 | g2225 | g2225.t3 | TTS | g2225.t3 | NA | NA |
Sequences
>g2225.t3 Gene=g2225 Length=958
ATGGCTTCAGCAGTCATCAACCACGAAACGAGCGGCAGTGGTATGAGCGAAAATGTTGCC
AGAAAGCAAATTAAAGTGGATTCGAGTCGTCAAACAAATATTTTGAGAATAAAAGCCAGG
AAAGCCAAAATATATCAATTGCCACGGTCGCAAAAGCTAGCTAAAATTTCGATGTATTCA
CAATGCAATCAGCAGTGTGGATGCAAAGGTTGGCGTTTACCAGAAGAGTCGAGACATAAA
GATGTTGAAATTGATCATTGTCCAAACATCAATGATTTGTGTCGTAATGCAAATTGTAAA
CACCCATTAGAATCACATTTTGCTCATATTAAAAATATTTCAAATGAACAAATGGATCAG
CTTCTCTCAATTATTGTTGATGCTGAAGTACTTTATACAACACTTGGTCTTCAAAAAGAT
AAATTTATCAAAAAGATTTACTCATTTCTGTTTACATTCTTACATCAATGTGTTGCTGAA
CGTAAACCAGCGATAATTCAAGGTCCCTTGGGTGATCCAGAAAAGAGCTTTGAAAAACCA
TCAATACAGAAAATAATTAAAAATTTTGTGGTTTTGAAGTATGATAAATTACGCGAGAAT
AATGAACCAGAATTTAAAGTTATCATGGAAGTTGCAAGAACATTTCTGAATTGTTATAAT
AACTGGGACTTTGAAATACCAAATGACTGTAAAGATGCAAATGCTGAAGAAAATTTTTAT
AAAATTGATTACACACGTTGGCTAGTTTTTTGTTATGTTCCATCATTCTGTAATAGTTTA
AAATACTACAATTGCAGTGAAATCTTTGGAAAGAGATTTTTGTTTTATACATTTCCTTTT
CTTTCACAACAATTTCTCTCACATTATGAGATTGAAAAGGAAAGTTTACCGCTTGAAAAA
CAAATTTTACTCGAACGTTTGCCAAAATTCCTTGAAACACTTCGTGAAGAGCTAAAAA
>g2225.t3 Gene=g2225 Length=319
MASAVINHETSGSGMSENVARKQIKVDSSRQTNILRIKARKAKIYQLPRSQKLAKISMYS
QCNQQCGCKGWRLPEESRHKDVEIDHCPNINDLCRNANCKHPLESHFAHIKNISNEQMDQ
LLSIIVDAEVLYTTLGLQKDKFIKKIYSFLFTFLHQCVAERKPAIIQGPLGDPEKSFEKP
SIQKIIKNFVVLKYDKLRENNEPEFKVIMEVARTFLNCYNNWDFEIPNDCKDANAEENFY
KIDYTRWLVFCYVPSFCNSLKYYNCSEIFGKRFLFYTFPFLSQQFLSHYEIEKESLPLEK
QILLERLPKFLETLREELK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g2225.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 21 | - |
| 5 | g2225.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 18 | - |
| 2 | g2225.t3 | PANTHER | PTHR45750:SF2 | HISTONE ACETYLTRANSFERASE KAT2B | 14 | 318 | 1.4E-56 |
| 3 | g2225.t3 | PANTHER | PTHR45750 | GH11602P | 14 | 318 | 1.4E-56 |
| 1 | g2225.t3 | Pfam | PF06466 | PCAF (P300/CBP-associated factor) N-terminal domain | 36 | 286 | 2.8E-74 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005634 | nucleus | CC |
| GO:0006355 | regulation of transcription, DNA-templated | BP |
| GO:0004402 | histone acetyltransferase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
