General information for g223.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dynamin-1-like protein.
Parent gene
- The parent gene g223 is located on chr_3: 1863487..1870063 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g223 | g223.t1 | TTS | g223.t1 | 1863484 | 1863484 |
| chr_3 | g223 | g223.t1 | isoform | g223.t1 | 1863487 | 1870063 |
| chr_3 | g223 | g223.t1 | exon | g223.t1.exon1 | 1863487 | 1863836 |
| chr_3 | g223 | g223.t1 | cds | g223.t1.CDS1 | 1863487 | 1863836 |
| chr_3 | g223 | g223.t1 | exon | g223.t1.exon2 | 1863909 | 1865165 |
| chr_3 | g223 | g223.t1 | cds | g223.t1.CDS2 | 1863909 | 1865165 |
| chr_3 | g223 | g223.t1 | exon | g223.t1.exon3 | 1869946 | 1870063 |
| chr_3 | g223 | g223.t1 | cds | g223.t1.CDS3 | 1869946 | 1870063 |
| chr_3 | g223 | g223.t1 | TSS | g223.t1 | NA | NA |
Sequences
>g223.t1 Gene=g223 Length=1725
ATGCGAAAAGTTTTTGATGAGATTTTTTGCAAAAAAGAAATTGAGAAAATAGAGCCTCAA
ATTCAAAAGCAAGATATTATTGTCTACATGAATCACAGTGGTGGACCAAGACCAGATGAA
ATTGAAGATCAAACAGATCTTATTGCTGGAAGTAACAAAGGCATATGTGCAGAACCGATC
AATTTAAAAATTTTCTCACCAGAAGTTGTCAATTTGACTCTTGTCGATTTGCCTGGTATT
ACAAAAGTTCCTGTTGGTGACCAACCGGAAGATATTGAAGATCAAATCAAGAGTCTTGTT
ATGGAATATATCAAAAATCCAAATTCAATCATTTTGAGTGTTAGTGCAGCAAATGTTGAT
TTGGCAACAAGTGAGAGCTTGAAATATGCAAAAGAAGTCGATCCTGATGGTAAACGTACA
TTAGCTGTTTTGACAAAAATTGATTTGATGGATGCAGGTACTGATGCGAATGAAATGCTT
ACTGGTGCAGTCATTCCTGTAAAACTTGGTATTGTTGGTGTCATCAATCGCTCACAACTT
GATATCAATAATAATAAAACTATCGCTGAGCAACTTGAGGATGAAAAGGAGTACTTTGCC
AAAAATTATAAGAAGATTGCAAGTCATAATGGAATTCCTCATCTTGAGCAACGTTTAAGC
AAGTTATTGATGAACCATATTTACGAATGTTTGCCAAATCTCAAGAAGGAAGTTCAAATG
AAGCGAGTTGAATGGCAAAACATTTTCGATCAATGTGGTGAAGAACTCACAAATCCTGAT
AAAATTTTTATGAAGATTATCACAAGTATTACAAACGATTTTCGCGGTAGCATTGATGGC
ACAACATTAAAAGTCGAACGCAATGCTAAAAACGTTTTTGGTGGACCAGCTATGCGAAAA
GTTTTTGATGAGATTTTTGCAAAAGAAATTGAGAAAATAGAGCCTCAAATTTCAAAGCAA
GATATTATTGTCTACATGAATCACAGTGGTGGACCAAGACCAGATGTTTTTGCACCTGAA
AAGTTGTTTGAAAAACTCATAAAAGAGAACATTGAGCGTTTGCAAGCTCCATCGCTCGAT
TGCTTGCAACATATTCATAACGAAATCGATAAAGTCATCAAAATGATTCTCAAAAATAAT
TTCGAGTTGAATCGTTTTCCAAAGTTGGCAGGAAGAATCAAATATATGCTTATTGAATTT
TTGAATGAGCGTTTATCAGAAACAGAAAGTTATCTAAAATATTTGATCAAAGCTGAGTTG
GCATCTATCAATAAGAATCATCCAGAGTTTTCAATTGAAGAAGCACTTAAGAAATTGGAC
ATTGAAGAAGACTACCACAACAAAAATGACGAATATGATGATGATGAAGGAAATGGTTTT
ATTTTTCAAAATGTTATGCGTACTGTACAAAAGCAAGTAAGAGCAGTTTTTCAGCAAAAG
AGAACCAAATGCCATGCTGAAATCATTGAAAATCTTGTTTTAAATTATTTTCCAATCGTA
AAGAAAACTGTGCAAGATTTAACTCCCAAAATCATCATGCATTCAATGGTCAATGACATG
TGTGACAATATATATAGTATGCTGATGGTTTTGTATAAAGACATTCATGATTTAATGAAC
GAGTCTAAAGATAACACTGATAAACGTAATGAAGCAAAGGATATGTTGAAAGCTCTAAAA
ATTGCTGATTCAACTATAAATCAAGTTTATGAAACTGAAATTTAA
>g223.t1 Gene=g223 Length=574
MRKVFDEIFCKKEIEKIEPQIQKQDIIVYMNHSGGPRPDEIEDQTDLIAGSNKGICAEPI
NLKIFSPEVVNLTLVDLPGITKVPVGDQPEDIEDQIKSLVMEYIKNPNSIILSVSAANVD
LATSESLKYAKEVDPDGKRTLAVLTKIDLMDAGTDANEMLTGAVIPVKLGIVGVINRSQL
DINNNKTIAEQLEDEKEYFAKNYKKIASHNGIPHLEQRLSKLLMNHIYECLPNLKKEVQM
KRVEWQNIFDQCGEELTNPDKIFMKIITSITNDFRGSIDGTTLKVERNAKNVFGGPAMRK
VFDEIFAKEIEKIEPQISKQDIIVYMNHSGGPRPDVFAPEKLFEKLIKENIERLQAPSLD
CLQHIHNEIDKVIKMILKNNFELNRFPKLAGRIKYMLIEFLNERLSETESYLKYLIKAEL
ASINKNHPEFSIEEALKKLDIEEDYHNKNDEYDDDEGNGFIFQNVMRTVQKQVRAVFQQK
RTKCHAEIIENLVLNYFPIVKKTVQDLTPKIIMHSMVNDMCDNIYSMLMVLYKDIHDLMN
ESKDNTDKRNEAKDMLKALKIADSTINQVYETEI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g223.t1 | CDD | cd08771 | DLP_1 | 38 | 232 | 6.63904E-89 |
| 14 | g223.t1 | Coils | Coil | Coil | 175 | 195 | - |
| 13 | g223.t1 | Gene3D | G3DSA:3.40.50.300 | - | 11 | 241 | 2.0E-73 |
| 5 | g223.t1 | PANTHER | PTHR11566:SF39 | DYNAMIN-1-LIKE PROTEIN | 39 | 455 | 9.2E-143 |
| 7 | g223.t1 | PANTHER | PTHR11566 | DYNAMIN | 39 | 455 | 9.2E-143 |
| 4 | g223.t1 | PANTHER | PTHR11566:SF39 | DYNAMIN-1-LIKE PROTEIN | 481 | 573 | 9.2E-143 |
| 6 | g223.t1 | PANTHER | PTHR11566 | DYNAMIN | 481 | 573 | 9.2E-143 |
| 9 | g223.t1 | PRINTS | PR00195 | Dynamin signature | 66 | 83 | 2.5E-32 |
| 11 | g223.t1 | PRINTS | PR00195 | Dynamin signature | 116 | 134 | 2.5E-32 |
| 10 | g223.t1 | PRINTS | PR00195 | Dynamin signature | 135 | 151 | 2.5E-32 |
| 8 | g223.t1 | PRINTS | PR00195 | Dynamin signature | 158 | 177 | 2.5E-32 |
| 3 | g223.t1 | Pfam | PF00350 | Dynamin family | 39 | 147 | 7.6E-27 |
| 2 | g223.t1 | Pfam | PF01031 | Dynamin central region | 158 | 433 | 2.8E-71 |
| 1 | g223.t1 | Pfam | PF02212 | Dynamin GTPase effector domain | 482 | 569 | 1.2E-18 |
| 18 | g223.t1 | ProSiteProfiles | PS51718 | Dynamin-type guanine nucleotide-binding (G) domain profile. | 1 | 232 | 35.941 |
| 19 | g223.t1 | ProSiteProfiles | PS51388 | GED domain profile. | 486 | 574 | 17.238 |
| 17 | g223.t1 | SMART | SM00053 | dynamin_3 | 14 | 185 | 4.0E-42 |
| 16 | g223.t1 | SMART | SM00302 | GED_2 | 481 | 569 | 2.3E-16 |
| 12 | g223.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 26 | 239 | 2.67E-46 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005525 | GTP binding | MF |
| GO:0016559 | peroxisome fission | BP |
| GO:0003924 | GTPase activity | MF |
| GO:0000266 | mitochondrial fission | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
